Assignment3
Xumin Shen
2023-10-30
library(dplyr)##
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## exprs, fData, fData<-, pData, pData<-setwd("/Users/azizilab/Documents/BMEN4500/dataset1/")
cds <- readRDS("dataset1.rds")
columndata <- cds %>% colData() %>% as.data.frame()
rowdata <- cds %>% rowData()%>%as.data.frame()Q1. Gene set analysis. Q1-2. Examine the top-upregulated gene (i.e., the gene with the highest normalized effect and under the q_value cutoff) as a function of treatment. Using a violin plot, plot the expression of this gene as a function of treatment (remember to add a pseudocount of 1). Describe the function of the product of this gene. Are the changes in its expression level consistent with the mechanism of action of the treatment that cells were exposed to? [10 pts]
# resd in DEG from assignment2
test_res <- read.table("test_res.txt", header = TRUE, sep = "\t")
sig_res<-test_res[test_res$q_value<0.01,]df_sorted <- sig_res[order(sig_res$normalized_effect,decreasing = TRUE), ]
#df_sortedplot_genes_violin(cds[rowData(cds)$gene_short_name == "GDF15",], group_cells_by = "treatment", pseudocount = 1) + ggpubr::stat_compare_means(method = "wilcox.test",label = "p.signif")## Warning: Transformation introduced infinite values in continuous y-axis
GDF15 is a member of the transforming growth factor β (TGF-β) superfamily, which includes various cytokines involved in regulating developmental processes and cellular responses. GDF15 itself has several key biological functions:
Regulation of Inflammatory Responses: GDF15 plays a role in modulating inflammatory and apoptotic pathways in injured tissues and during certain diseases. It is often upregulated in response to acute injury, inflammation, and during oxidative stress.
Role in Disease: Elevated levels of GDF15 are associated with a range of diseases, including cardiovascular diseases, cancer, and others. Its expression is often indicative of cellular stress or disease states.
Cancer and Cellular Stress Response: In the context of cancer, GDF15 can have diverse roles. It’s known to be involved in tumor suppression and progression, and its expression is often upregulated in response to cellular stress and DNA damage.
Cellular Growth and Apoptosis: It can influence processes like cell growth, differentiation, and apoptosis, although its exact role can vary depending on the tissue and context.
From this violin plot, we can see that gene GDF15 express much more under the treatment (doxorubicin).
Doxorubicin is a chemotherapy medication used mainly in cancer treatment. It works primarily by intercalating DNA, disrupting topoisomerase-II-mediated DNA repair, and generating free radicals that damage cellular components.
The upregulation of GDF15 in response to doxorubicin treatment aligns well with its known functions. Doxorubicin induces cellular stress, DNA damage, and apoptotic responses. Given GDF15’s role in responding to stress, inflammation, and damage at the cellular level, its increased expression could be indicative of the cells’ response to the DNA damage and oxidative stress caused by doxorubicin.
The heightened expression of GDF15 could therefore be seen as a biomarker for cellular responses to chemotherapy agents like doxorubicin and may also contribute to the molecular mechanisms of drug action, such as by mediating inflammatory responses or cell survival pathways.
Q1-2. Identify the top 100 upregulated and top 100 downregulated genes and save their HUGO gene symbols (i.e., their gene_short_name). Using the Reactome Pathway Database Analysis tool (https://reactome.org/PathwayBrowser/#TOOL=AT), identify gene terms associated with each set of genes. Examine and provide the top gene sets (e.g., the first 5-10 associated gene sets). What can you conclude of the effects of treatment on cells given the biological pathways that gene set analysis identifies as associated with your differentially expressed genes? [10 pts]
#df_sortedup100gene = df_sorted[1:100,]$gene_short_name
writeLines(up100gene, "up100gene.txt")
last_100 <- tail(df_sorted, 100)
down100gene<-last_100$gene_short_name
writeLines(down100gene, "down100gene.txt")
For the top 100 upregulated genes:
result_up <- read.csv("result_up.csv")
result_up## Pathway.identifier
## 1 R-HSA-141444
## 2 R-HSA-141424
## 3 R-HSA-69618
## 4 R-HSA-2500257
## 5 R-HSA-68877
## 6 R-HSA-69278
## 7 R-HSA-1640170
## 8 R-HSA-68886
## 9 R-HSA-9648025
## 10 R-HSA-69620
## 11 R-HSA-2555396
## 12 R-HSA-68882
## 13 R-HSA-2467813
## 14 R-HSA-5663220
## 15 R-HSA-195258
## 16 R-HSA-453279
## 17 R-HSA-156711
## 18 R-HSA-1538133
## 19 R-HSA-69205
## 20 R-HSA-69273
## 21 R-HSA-69275
## 22 R-HSA-453274
## 23 R-HSA-194315
## 24 R-HSA-1362300
## 25 R-HSA-9716542
## 26 R-HSA-69206
## 27 R-HSA-453276
## 28 R-HSA-174143
## 29 R-HSA-176814
## 30 R-HSA-2514853
## 31 R-HSA-73886
## 32 R-HSA-983189
## 33 R-HSA-69481
## 34 R-HSA-179419
## 35 R-HSA-69478
## 36 R-HSA-176409
## 37 R-HSA-176417
## 38 R-HSA-176408
## 39 R-HSA-2980767
## 40 R-HSA-179409
## 41 R-HSA-774815
## 42 R-HSA-606279
## 43 R-HSA-6811434
## 44 R-HSA-68884
## 45 R-HSA-174184
## 46 R-HSA-162658
## 47 R-HSA-69242
## 48 R-HSA-176412
## 49 R-HSA-141405
## 50 R-HSA-141430
## 51 R-HSA-6804114
## 52 R-HSA-2565942
## 53 R-HSA-170145
## 54 R-HSA-9675135
## 55 R-HSA-174048
## 56 R-HSA-9709603
## 57 R-HSA-8856688
## 58 R-HSA-9701193
## 59 R-HSA-9704331
## 60 R-HSA-9701192
## 61 R-HSA-9704646
## 62 R-HSA-6791312
## 63 R-HSA-5693554
## 64 R-HSA-113507
## 65 R-HSA-8869496
## 66 R-HSA-174178
## 67 R-HSA-5693568
## 68 R-HSA-5693537
## 69 R-HSA-69239
## 70 R-HSA-176187
## 71 R-HSA-983231
## 72 R-HSA-8852276
## 73 R-HSA-9701190
## 74 R-HSA-9675136
## 75 R-HSA-2465910
## 76 R-HSA-176974
## 77 R-HSA-2468052
## 78 R-HSA-5693579
## 79 R-HSA-6811442
## 80 R-HSA-75035
## 81 R-HSA-4615885
## 82 R-HSA-9636003
## 83 R-HSA-9629232
## 84 R-HSA-69306
## 85 R-HSA-176407
## 86 R-HSA-2980766
## 87 R-HSA-5625900
## 88 R-HSA-5693567
## 89 R-HSA-180786
## 90 R-HSA-113510
## 91 R-HSA-9763198
## 92 R-HSA-9709275
## 93 R-HSA-1362277
## 94 R-HSA-5693538
## 95 R-HSA-380284
## 96 R-HSA-380259
## 97 R-HSA-5685942
## 98 R-HSA-68875
## 99 R-HSA-2995383
## 100 R-HSA-8854518
## 101 R-HSA-2132295
## 102 R-HSA-69473
## 103 R-HSA-380270
## 104 R-HSA-380287
## 105 R-HSA-171319
## 106 R-HSA-9709570
## 107 R-HSA-68962
## 108 R-HSA-68881
## 109 R-HSA-69052
## 110 R-HSA-69190
## 111 R-HSA-6804756
## 112 R-HSA-380320
## 113 R-HSA-5693532
## 114 R-HSA-5620912
## 115 R-HSA-5693616
## 116 R-HSA-3301854
## 117 R-HSA-9696273
## 118 R-HSA-6804757
## 119 R-HSA-5633007
## 120 R-HSA-9696270
## 121 R-HSA-157579
## 122 R-HSA-8953750
## 123 R-HSA-6806003
## 124 R-HSA-68911
## 125 R-HSA-8864260
## 126 R-HSA-68689
## 127 R-HSA-9605308
## 128 R-HSA-2299718
## 129 R-HSA-140180
## 130 R-HSA-912446
## 131 R-HSA-1296052
## 132 R-HSA-69002
## 133 R-HSA-174154
## 134 R-HSA-110056
## 135 R-HSA-68949
## 136 R-HSA-69017
## 137 R-HSA-5685939
## 138 R-HSA-418457
## 139 R-HSA-2995410
## 140 R-HSA-9687136
## 141 R-HSA-6804116
## 142 R-HSA-5693607
## 143 R-HSA-2559582
## 144 R-HSA-3700989
## 145 R-HSA-1500620
## 146 R-HSA-73894
## 147 R-HSA-5358606
## 148 R-HSA-5358565
## 149 R-HSA-400511
## 150 R-HSA-3108232
## 151 R-HSA-4419969
## 152 R-HSA-5358508
## 153 R-HSA-2990846
## 154 R-HSA-422085
## 155 R-HSA-112409
## 156 R-HSA-6804115
## 157 R-HSA-9013507
## 158 R-HSA-5617833
## 159 R-HSA-8863678
## 160 R-HSA-8862803
## 161 R-HSA-68867
## 162 R-HSA-174411
## 163 R-HSA-8866652
## 164 R-HSA-9734009
## 165 R-HSA-73614
## 166 R-HSA-392154
## 167 R-HSA-9687139
## 168 R-HSA-110330
## 169 R-HSA-9675126
## 170 R-HSA-5685938
## 171 R-HSA-9013424
## 172 R-HSA-68616
## 173 R-HSA-9022692
## 174 R-HSA-110328
## 175 R-HSA-6809371
## 176 R-HSA-9696264
## 177 R-HSA-110331
## 178 R-HSA-9013420
## 179 R-HSA-5689896
## 180 R-HSA-73927
## 181 R-HSA-1474165
## 182 R-HSA-9035034
## 183 R-HSA-381771
## 184 R-HSA-8853884
## 185 R-HSA-174417
## 186 R-HSA-110329
## 187 R-HSA-73928
## 188 R-HSA-400508
## 189 R-HSA-174113
## 190 R-HSA-9604323
## 191 R-HSA-9013405
## 192 R-HSA-2162123
## 193 R-HSA-162582
## 194 R-HSA-5688426
## 195 R-HSA-9013409
## 196 R-HSA-199991
## 197 R-HSA-212436
## 198 R-HSA-109582
## 199 R-HSA-187577
## 200 R-HSA-73929
## 201 R-HSA-9013406
## 202 R-HSA-9012852
## 203 R-HSA-174084
## 204 R-HSA-193648
## 205 R-HSA-8956321
## 206 R-HSA-2559586
## 207 R-HSA-69563
## 208 R-HSA-69580
## 209 R-HSA-983168
## 210 R-HSA-9013149
## 211 R-HSA-69615
## 212 R-HSA-9013026
## 213 R-HSA-2559583
## 214 R-HSA-9013408
## 215 R-HSA-9013106
## 216 R-HSA-5625740
## 217 R-HSA-975634
## 218 R-HSA-5689880
## 219 R-HSA-499943
## 220 R-HSA-1852241
## 221 R-HSA-204998
## 222 R-HSA-8852135
## 223 R-HSA-383280
## 224 R-HSA-416482
## 225 R-HSA-69202
## 226 R-HSA-9833482
## 227 R-HSA-6806667
## 228 R-HSA-69656
## 229 R-HSA-73857
## 230 R-HSA-9013404
## 231 R-HSA-9013694
## 232 R-HSA-6805567
## 233 R-HSA-9645723
## 234 R-HSA-73884
## 235 R-HSA-1280218
## 236 R-HSA-9013423
## 237 R-HSA-8986944
## 238 R-HSA-5687128
## 239 R-HSA-1296071
## 240 R-HSA-193704
## 241 R-HSA-15869
## 242 R-HSA-5653656
## 243 R-HSA-163125
## 244 R-HSA-983169
## 245 R-HSA-418346
## 246 R-HSA-1799339
## 247 R-HSA-2980736
## 248 R-HSA-74160
## 249 R-HSA-9012999
## 250 R-HSA-8878166
## 251 R-HSA-8980692
## 252 R-HSA-9013148
## 253 R-HSA-2142753
## 254 R-HSA-2187338
## 255 R-HSA-73887
## 256 R-HSA-1169410
## 257 R-HSA-157118
## 258 R-HSA-211945
## 259 R-HSA-5684996
## 260 R-HSA-597592
## 261 R-HSA-72766
## 262 R-HSA-5683057
## 263 R-HSA-196854
## 264 R-HSA-913531
## 265 R-HSA-8978868
## 266 R-HSA-112316
## 267 R-HSA-211859
## 268 R-HSA-392499
## 269 R-HSA-2262752
## 270 R-HSA-8953897
## 271 R-HSA-388396
## 272 R-HSA-372790
## 273 R-HSA-168256
## 274 R-HSA-1280215
## 275 R-HSA-1266738
## 276 R-HSA-1643685
## 277 R-HSA-9709957
## 278 R-HSA-556833
## 279 R-HSA-1430728
## Pathway.name
## 1 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
## 2 Amplification of signal from the kinetochores
## 3 Mitotic Spindle Checkpoint
## 4 Resolution of Sister Chromatid Cohesion
## 5 Mitotic Prometaphase
## 6 Cell Cycle, Mitotic
## 7 Cell Cycle
## 8 M Phase
## 9 EML4 and NUDC in mitotic spindle formation
## 10 Cell Cycle Checkpoints
## 11 Mitotic Metaphase and Anaphase
## 12 Mitotic Anaphase
## 13 Separation of Sister Chromatids
## 14 RHO GTPases Activate Formins
## 15 RHO GTPase Effectors
## 16 Mitotic G1 phase and G1/S transition
## 17 Polo-like kinase mediated events
## 18 G0 and Early G1
## 19 G1/S-Specific Transcription
## 20 Cyclin A/B1/B2 associated events during G2/M transition
## 21 G2/M Transition
## 22 Mitotic G2-G2/M phases
## 23 Signaling by Rho GTPases
## 24 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
## 25 Signaling by Rho GTPases, Miro GTPases and RHOBTB3
## 26 G1/S Transition
## 27 Regulation of mitotic cell cycle
## 28 APC/C-mediated degradation of cell cycle proteins
## 29 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
## 30 Condensation of Prometaphase Chromosomes
## 31 Chromosome Maintenance
## 32 Kinesins
## 33 G2/M Checkpoints
## 34 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
## 35 G2/M DNA replication checkpoint
## 36 APC/C:Cdc20 mediated degradation of mitotic proteins
## 37 Phosphorylation of Emi1
## 38 Regulation of APC/C activators between G1/S and early anaphase
## 39 Activation of NIMA Kinases NEK9, NEK6, NEK7
## 40 APC-Cdc20 mediated degradation of Nek2A
## 41 Nucleosome assembly
## 42 Deposition of new CENPA-containing nucleosomes at the centromere
## 43 COPI-dependent Golgi-to-ER retrograde traffic
## 44 Mitotic Telophase/Cytokinesis
## 45 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
## 46 Golgi Cisternae Pericentriolar Stack Reorganization
## 47 S Phase
## 48 Phosphorylation of the APC/C
## 49 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
## 50 Inactivation of APC/C via direct inhibition of the APC/C complex
## 51 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
## 52 Regulation of PLK1 Activity at G2/M Transition
## 53 Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
## 54 Diseases of DNA repair
## 55 APC/C:Cdc20 mediated degradation of Cyclin B
## 56 Impaired BRCA2 binding to PALB2
## 57 Golgi-to-ER retrograde transport
## 58 Defective homologous recombination repair (HRR) due to PALB2 loss of function
## 59 Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
## 60 Defective homologous recombination repair (HRR) due to BRCA1 loss of function
## 61 Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
## 62 TP53 Regulates Transcription of Cell Cycle Genes
## 63 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
## 64 E2F-enabled inhibition of pre-replication complex formation
## 65 TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
## 66 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
## 67 Resolution of D-loop Structures through Holliday Junction Intermediates
## 68 Resolution of D-Loop Structures
## 69 Synthesis of DNA
## 70 Activation of ATR in response to replication stress
## 71 Factors involved in megakaryocyte development and platelet production
## 72 The role of GTSE1 in G2/M progression after G2 checkpoint
## 73 Defective homologous recombination repair (HRR) due to BRCA2 loss of function
## 74 Diseases of DNA Double-Strand Break Repair
## 75 MASTL Facilitates Mitotic Progression
## 76 Unwinding of DNA
## 77 Establishment of Sister Chromatid Cohesion
## 78 Homologous DNA Pairing and Strand Exchange
## 79 Intra-Golgi and retrograde Golgi-to-ER traffic
## 80 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
## 81 SUMOylation of DNA replication proteins
## 82 NEIL3-mediated resolution of ICLs
## 83 Defective Base Excision Repair Associated with NEIL3
## 84 DNA Replication
## 85 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
## 86 Nuclear Envelope Breakdown
## 87 RHO GTPases activate CIT
## 88 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
## 89 Extension of Telomeres
## 90 E2F mediated regulation of DNA replication
## 91 Impaired BRCA2 binding to SEM1 (DSS1)
## 92 Impaired BRCA2 translocation to the nucleus
## 93 Transcription of E2F targets under negative control by DREAM complex
## 94 Homology Directed Repair
## 95 Loss of proteins required for interphase microtubule organization from the centrosome
## 96 Loss of Nlp from mitotic centrosomes
## 97 HDR through Homologous Recombination (HRR)
## 98 Mitotic Prophase
## 99 Initiation of Nuclear Envelope (NE) Reformation
## 100 AURKA Activation by TPX2
## 101 MHC class II antigen presentation
## 102 G2/M DNA damage checkpoint
## 103 Recruitment of mitotic centrosome proteins and complexes
## 104 Centrosome maturation
## 105 Telomere Extension By Telomerase
## 106 Impaired BRCA2 binding to RAD51
## 107 Activation of the pre-replicative complex
## 108 Mitotic Metaphase/Anaphase Transition
## 109 Switching of origins to a post-replicative state
## 110 DNA strand elongation
## 111 Regulation of TP53 Activity through Phosphorylation
## 112 Recruitment of NuMA to mitotic centrosomes
## 113 DNA Double-Strand Break Repair
## 114 Anchoring of the basal body to the plasma membrane
## 115 Presynaptic phase of homologous DNA pairing and strand exchange
## 116 Nuclear Pore Complex (NPC) Disassembly
## 117 RND1 GTPase cycle
## 118 Regulation of TP53 Degradation
## 119 Regulation of TP53 Activity
## 120 RND2 GTPase cycle
## 121 Telomere Maintenance
## 122 Transcriptional Regulation by E2F6
## 123 Regulation of TP53 Expression and Degradation
## 124 G2 Phase
## 125 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
## 126 CDC6 association with the ORC:origin complex
## 127 Diseases of Base Excision Repair
## 128 Condensation of Prophase Chromosomes
## 129 COX reactions
## 130 Meiotic recombination
## 131 Ca2+ activated K+ channels
## 132 DNA Replication Pre-Initiation
## 133 APC/C:Cdc20 mediated degradation of Securin
## 134 MAPK3 (ERK1) activation
## 135 Orc1 removal from chromatin
## 136 CDK-mediated phosphorylation and removal of Cdc6
## 137 HDR through MMEJ (alt-NHEJ)
## 138 cGMP effects
## 139 Nuclear Envelope (NE) Reassembly
## 140 Aberrant regulation of mitotic exit in cancer due to RB1 defects
## 141 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
## 142 Processing of DNA double-strand break ends
## 143 Senescence-Associated Secretory Phenotype (SASP)
## 144 Transcriptional Regulation by TP53
## 145 Meiosis
## 146 DNA Repair
## 147 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
## 148 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
## 149 Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
## 150 SUMO E3 ligases SUMOylate target proteins
## 151 Depolymerization of the Nuclear Lamina
## 152 Mismatch Repair
## 153 SUMOylation
## 154 Synthesis, secretion, and deacylation of Ghrelin
## 155 RAF-independent MAPK1/3 activation
## 156 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
## 157 NOTCH3 Activation and Transmission of Signal to the Nucleus
## 158 Cilium Assembly
## 159 Neurodegenerative Diseases
## 160 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
## 161 Assembly of the pre-replicative complex
## 162 Polymerase switching on the C-strand of the telomere
## 163 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
## 164 Defective Intrinsic Pathway for Apoptosis
## 165 Pyrimidine salvage
## 166 Nitric oxide stimulates guanylate cyclase
## 167 Aberrant regulation of mitotic cell cycle due to RB1 defects
## 168 Recognition and association of DNA glycosylase with site containing an affected purine
## 169 Diseases of mitotic cell cycle
## 170 HDR through Single Strand Annealing (SSA)
## 171 RHOV GTPase cycle
## 172 Assembly of the ORC complex at the origin of replication
## 173 Regulation of MECP2 expression and activity
## 174 Recognition and association of DNA glycosylase with site containing an affected pyrimidine
## 175 Formation of the cornified envelope
## 176 RND3 GTPase cycle
## 177 Cleavage of the damaged purine
## 178 RHOU GTPase cycle
## 179 Ovarian tumor domain proteases
## 180 Depurination
## 181 Reproduction
## 182 RHOF GTPase cycle
## 183 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
## 184 Transcriptional Regulation by VENTX
## 185 Telomere C-strand (Lagging Strand) Synthesis
## 186 Cleavage of the damaged pyrimidine
## 187 Depyrimidination
## 188 Incretin synthesis, secretion, and inactivation
## 189 SCF-beta-TrCP mediated degradation of Emi1
## 190 Negative regulation of NOTCH4 signaling
## 191 RHOD GTPase cycle
## 192 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
## 193 Signal Transduction
## 194 Deubiquitination
## 195 RHOJ GTPase cycle
## 196 Membrane Trafficking
## 197 Generic Transcription Pathway
## 198 Hemostasis
## 199 SCF(Skp2)-mediated degradation of p27/p21
## 200 Base-Excision Repair, AP Site Formation
## 201 RHOQ GTPase cycle
## 202 Signaling by NOTCH3
## 203 Autodegradation of Cdh1 by Cdh1:APC/C
## 204 NRAGE signals death through JNK
## 205 Nucleotide salvage
## 206 DNA Damage/Telomere Stress Induced Senescence
## 207 p53-Dependent G1 DNA Damage Response
## 208 p53-Dependent G1/S DNA damage checkpoint
## 209 Antigen processing: Ubiquitination & Proteasome degradation
## 210 RAC1 GTPase cycle
## 211 G1/S DNA Damage Checkpoints
## 212 RHOB GTPase cycle
## 213 Cellular Senescence
## 214 RHOG GTPase cycle
## 215 RHOC GTPase cycle
## 216 RHO GTPases activate PKNs
## 217 Retinoid metabolism and transport
## 218 Ub-specific processing proteases
## 219 Interconversion of nucleotide di- and triphosphates
## 220 Organelle biogenesis and maintenance
## 221 Cell death signalling via NRAGE, NRIF and NADE
## 222 Protein ubiquitination
## 223 Nuclear Receptor transcription pathway
## 224 G alpha (12/13) signalling events
## 225 Cyclin E associated events during G1/S transition
## 226 PKR-mediated signaling
## 227 Metabolism of fat-soluble vitamins
## 228 Cyclin A:Cdk2-associated events at S phase entry
## 229 RNA Polymerase II Transcription
## 230 RAC2 GTPase cycle
## 231 Signaling by NOTCH4
## 232 Keratinization
## 233 Diseases of programmed cell death
## 234 Base Excision Repair
## 235 Adaptive Immune System
## 236 RAC3 GTPase cycle
## 237 Transcriptional Regulation by MECP2
## 238 MAPK6/MAPK4 signaling
## 239 Potassium Channels
## 240 p75 NTR receptor-mediated signalling
## 241 Metabolism of nucleotides
## 242 Vesicle-mediated transport
## 243 Post-translational modification: synthesis of GPI-anchored proteins
## 244 Class I MHC mediated antigen processing & presentation
## 245 Platelet homeostasis
## 246 SRP-dependent cotranslational protein targeting to membrane
## 247 Peptide hormone metabolism
## 248 Gene expression (Transcription)
## 249 RHO GTPase cycle
## 250 Transcriptional regulation by RUNX2
## 251 RHOA GTPase cycle
## 252 CDC42 GTPase cycle
## 253 Arachidonic acid metabolism
## 254 Visual phototransduction
## 255 Death Receptor Signaling
## 256 Antiviral mechanism by IFN-stimulated genes
## 257 Signaling by NOTCH
## 258 Phase I - Functionalization of compounds
## 259 MAPK1/MAPK3 signaling
## 260 Post-translational protein modification
## 261 Translation
## 262 MAPK family signaling cascades
## 263 Metabolism of vitamins and cofactors
## 264 Interferon Signaling
## 265 Fatty acid metabolism
## 266 Neuronal System
## 267 Biological oxidations
## 268 Metabolism of proteins
## 269 Cellular responses to stress
## 270 Cellular responses to stimuli
## 271 GPCR downstream signalling
## 272 Signaling by GPCR
## 273 Immune System
## 274 Cytokine Signaling in Immune system
## 275 Developmental Biology
## 276 Disease
## 277 Sensory Perception
## 278 Metabolism of lipids
## 279 Metabolism
## X.Entities.found X.Entities.total Entities.ratio Entities.pValue
## 1 17 94 6.120987e-03 1.110223e-16
## 2 17 94 6.120987e-03 1.110223e-16
## 3 18 111 7.227974e-03 1.110223e-16
## 4 20 134 8.725663e-03 1.110223e-16
## 5 23 211 1.373966e-02 1.110223e-16
## 6 50 595 3.874455e-02 1.110223e-16
## 7 57 733 4.773068e-02 1.110223e-16
## 8 27 415 2.702351e-02 1.110223e-16
## 9 17 121 7.879143e-03 1.110223e-16
## 10 27 279 1.816761e-02 1.110223e-16
## 11 21 250 1.627922e-02 1.110223e-16
## 12 21 249 1.621410e-02 1.110223e-16
## 13 19 195 1.269779e-02 3.330669e-16
## 14 17 149 9.702416e-03 1.110223e-15
## 15 20 325 2.116299e-02 2.740030e-13
## 16 15 174 1.133034e-02 3.182010e-12
## 17 8 23 1.497688e-03 9.745205e-12
## 18 8 38 2.474442e-03 4.947870e-10
## 19 8 43 2.800026e-03 1.291102e-09
## 20 7 32 2.083740e-03 4.793114e-09
## 21 13 212 1.380478e-02 5.633088e-09
## 22 13 214 1.393501e-02 6.289009e-09
## 23 22 708 4.610275e-02 6.985262e-09
## 24 6 20 1.302338e-03 9.826404e-09
## 25 22 724 4.714462e-02 1.041762e-08
## 26 10 150 9.767533e-03 1.660732e-07
## 27 8 92 5.990753e-03 4.234569e-07
## 28 8 92 5.990753e-03 4.234569e-07
## 29 7 77 5.014000e-03 1.715723e-06
## 30 4 15 9.767533e-04 5.014547e-06
## 31 8 135 8.790779e-03 7.048719e-06
## 32 6 68 4.427948e-03 1.146755e-05
## 33 8 153 9.962883e-03 1.723925e-05
## 34 6 74 4.818649e-03 1.839134e-05
## 35 3 7 4.558182e-04 2.024641e-05
## 36 6 76 4.948883e-03 2.133249e-05
## 37 3 8 5.209351e-04 3.006342e-05
## 38 6 83 5.404701e-03 3.474673e-05
## 39 3 9 5.860520e-04 4.258054e-05
## 40 4 26 1.693039e-03 4.258247e-05
## 41 5 53 3.451195e-03 4.630353e-05
## 42 5 53 3.451195e-03 4.630353e-05
## 43 6 107 6.967507e-03 1.387039e-04
## 44 3 15 9.767533e-04 1.910132e-04
## 45 5 73 4.753533e-03 2.047638e-04
## 46 3 17 1.106987e-03 2.751549e-04
## 47 7 179 1.165592e-02 3.451362e-04
## 48 3 20 1.302338e-03 4.410492e-04
## 49 3 21 1.367455e-03 5.079004e-04
## 50 3 21 1.367455e-03 5.079004e-04
## 51 3 21 1.367455e-03 5.079004e-04
## 52 5 92 5.990753e-03 5.842231e-04
## 53 2 5 3.255844e-04 6.320506e-04
## 54 4 54 3.516312e-03 6.786299e-04
## 55 3 24 1.562805e-03 7.463278e-04
## 56 3 24 1.562805e-03 7.463278e-04
## 57 6 148 9.637299e-03 7.656277e-04
## 58 3 25 1.627922e-03 8.391554e-04
## 59 3 25 1.627922e-03 8.391554e-04
## 60 3 25 1.627922e-03 8.391554e-04
## 61 3 25 1.627922e-03 8.391554e-04
## 62 4 65 4.232598e-03 1.340853e-03
## 63 3 31 2.018623e-03 1.550534e-03
## 64 2 9 5.860520e-04 2.009593e-03
## 65 2 9 5.860520e-04 2.009593e-03
## 66 4 74 4.818649e-03 2.143658e-03
## 67 3 37 2.409325e-03 2.555062e-03
## 68 3 38 2.474442e-03 2.753486e-03
## 69 5 132 8.595429e-03 2.831097e-03
## 70 3 39 2.539559e-03 2.961164e-03
## 71 6 194 1.263268e-02 2.977050e-03
## 72 4 83 5.404701e-03 3.229102e-03
## 73 3 41 2.669792e-03 3.404832e-03
## 74 3 41 2.669792e-03 3.404832e-03
## 75 2 12 7.814026e-04 3.522541e-03
## 76 2 12 7.814026e-04 3.522541e-03
## 77 2 13 8.465195e-04 4.114710e-03
## 78 3 45 2.930260e-03 4.409011e-03
## 79 6 219 1.426060e-02 5.334691e-03
## 80 2 15 9.767533e-04 5.426959e-03
## 81 3 50 3.255844e-03 5.892909e-03
## 82 1 1 6.511688e-05 7.202149e-03
## 83 1 1 6.511688e-05 7.202149e-03
## 84 5 168 1.093964e-02 7.716410e-03
## 85 2 22 1.432571e-03 1.129745e-02
## 86 3 65 4.232598e-03 1.197899e-02
## 87 2 23 1.497688e-03 1.229027e-02
## 88 4 124 8.074494e-03 1.285940e-02
## 89 3 67 4.362831e-03 1.298431e-02
## 90 2 24 1.562805e-03 1.331986e-02
## 91 1 2 1.302338e-04 1.435289e-02
## 92 1 2 1.302338e-04 1.435289e-02
## 93 2 25 1.627922e-03 1.438566e-02
## 94 4 130 8.465195e-03 1.503669e-02
## 95 3 71 4.623299e-03 1.513586e-02
## 96 3 71 4.623299e-03 1.513586e-02
## 97 3 73 4.753533e-03 1.628261e-02
## 98 4 134 8.725663e-03 1.661010e-02
## 99 2 27 1.758156e-03 1.662365e-02
## 100 3 74 4.818649e-03 1.687382e-02
## 101 4 137 8.921013e-03 1.785548e-02
## 102 3 80 5.209351e-03 2.067197e-02
## 103 3 81 5.274468e-03 2.134692e-02
## 104 3 83 5.404701e-03 2.273282e-02
## 105 2 34 2.213974e-03 2.551610e-02
## 106 2 35 2.279091e-03 2.691391e-02
## 107 2 36 2.344208e-03 2.834205e-02
## 108 1 4 2.604675e-04 2.850161e-02
## 109 3 94 6.120987e-03 3.121210e-02
## 110 2 38 2.474442e-03 3.128728e-02
## 111 3 95 6.186104e-03 3.205454e-02
## 112 3 97 6.316338e-03 3.377497e-02
## 113 4 169 1.100475e-02 3.478586e-02
## 114 3 99 6.446572e-03 3.554263e-02
## 115 2 42 2.734909e-03 3.751994e-02
## 116 2 42 2.734909e-03 3.751994e-02
## 117 2 43 2.800026e-03 3.914660e-02
## 118 2 43 2.800026e-03 3.914660e-02
## 119 4 178 1.159081e-02 4.078856e-02
## 120 2 44 2.865143e-03 4.079974e-02
## 121 3 108 7.032624e-03 4.407518e-02
## 122 2 46 2.995377e-03 4.418358e-02
## 123 2 46 2.995377e-03 4.418358e-02
## 124 1 7 4.558182e-04 4.934813e-02
## 125 2 52 3.386078e-03 5.492370e-02
## 126 1 8 5.209351e-04 5.619798e-02
## 127 1 8 5.209351e-04 5.619798e-02
## 128 2 54 3.516312e-03 5.868846e-02
## 129 1 9 5.860520e-04 6.299891e-02
## 130 2 57 3.711662e-03 6.449736e-02
## 131 1 10 6.511688e-04 6.975128e-02
## 132 3 131 8.530312e-03 7.000479e-02
## 133 2 68 4.427948e-03 8.729744e-02
## 134 1 13 8.465195e-04 8.972039e-02
## 135 2 73 4.753533e-03 9.834779e-02
## 136 2 75 4.883766e-03 1.028736e-01
## 137 1 17 1.106987e-03 1.156865e-01
## 138 1 18 1.172104e-03 1.220625e-01
## 139 2 88 5.730286e-03 1.335588e-01
## 140 1 20 1.302338e-03 1.346781e-01
## 141 1 20 1.302338e-03 1.346781e-01
## 142 2 89 5.795403e-03 1.359992e-01
## 143 2 90 5.860520e-03 1.384495e-01
## 144 6 484 3.151657e-02 1.389627e-01
## 145 2 91 5.925637e-03 1.409097e-01
## 146 5 380 2.474442e-02 1.417000e-01
## 147 1 22 1.432571e-03 1.471140e-01
## 148 1 22 1.432571e-03 1.471140e-01
## 149 1 22 1.432571e-03 1.471140e-01
## 150 3 184 1.198151e-02 1.488875e-01
## 151 1 23 1.497688e-03 1.532654e-01
## 152 1 23 1.497688e-03 1.532654e-01
## 153 3 193 1.256756e-02 1.643652e-01
## 154 1 26 1.693039e-03 1.714570e-01
## 155 1 28 1.823273e-03 1.833691e-01
## 156 1 28 1.823273e-03 1.833691e-01
## 157 1 28 1.823273e-03 1.833691e-01
## 158 3 209 1.360943e-02 1.929779e-01
## 159 1 30 1.953507e-03 1.951113e-01
## 160 1 30 1.953507e-03 1.951113e-01
## 161 2 113 7.358208e-03 1.969984e-01
## 162 1 31 2.018623e-03 2.009196e-01
## 163 1 33 2.148857e-03 2.124117e-01
## 164 1 33 2.148857e-03 2.124117e-01
## 165 1 34 2.213974e-03 2.180962e-01
## 166 1 35 2.279091e-03 2.237400e-01
## 167 1 36 2.344208e-03 2.293435e-01
## 168 1 38 2.474442e-03 2.404305e-01
## 169 1 38 2.474442e-03 2.404305e-01
## 170 1 39 2.539559e-03 2.459145e-01
## 171 1 39 2.539559e-03 2.459145e-01
## 172 1 39 2.539559e-03 2.459145e-01
## 173 1 39 2.539559e-03 2.459145e-01
## 174 1 41 2.669792e-03 2.567652e-01
## 175 2 138 8.986130e-03 2.633001e-01
## 176 1 43 2.800026e-03 2.674611e-01
## 177 1 44 2.865143e-03 2.727517e-01
## 178 1 44 2.865143e-03 2.727517e-01
## 179 1 44 2.865143e-03 2.727517e-01
## 180 1 45 2.930260e-03 2.780045e-01
## 181 2 144 9.376831e-03 2.793252e-01
## 182 1 46 2.995377e-03 2.832196e-01
## 183 1 47 3.060494e-03 2.883974e-01
## 184 1 48 3.125610e-03 2.935382e-01
## 185 1 49 3.190727e-03 2.986421e-01
## 186 1 50 3.255844e-03 3.037095e-01
## 187 1 50 3.255844e-03 3.037095e-01
## 188 1 51 3.320961e-03 3.087406e-01
## 189 1 55 3.581429e-03 3.285073e-01
## 190 1 57 3.711662e-03 3.381796e-01
## 191 1 57 3.711662e-03 3.381796e-01
## 192 1 58 3.776779e-03 3.429638e-01
## 193 24 3031 1.973693e-01 3.445761e-01
## 194 3 289 1.881878e-02 3.475879e-01
## 195 1 59 3.841896e-03 3.477137e-01
## 196 6 668 4.349808e-02 3.532340e-01
## 197 13 1586 1.032754e-01 3.594231e-01
## 198 7 803 5.228886e-02 3.613657e-01
## 199 1 62 4.037247e-03 3.617604e-01
## 200 1 62 4.037247e-03 3.617604e-01
## 201 1 63 4.102364e-03 3.663756e-01
## 202 1 63 4.102364e-03 3.663756e-01
## 203 1 64 4.167481e-03 3.709578e-01
## 204 1 64 4.167481e-03 3.709578e-01
## 205 1 69 4.493065e-03 3.933808e-01
## 206 1 70 4.558182e-03 3.977694e-01
## 207 1 70 4.558182e-03 3.977694e-01
## 208 1 70 4.558182e-03 3.977694e-01
## 209 3 315 2.051182e-02 3.985612e-01
## 210 2 191 1.243732e-02 4.022570e-01
## 211 1 72 4.688416e-03 4.064524e-01
## 212 1 75 4.883766e-03 4.192449e-01
## 213 2 199 1.295826e-02 4.223139e-01
## 214 1 78 5.079117e-03 4.317641e-01
## 215 1 79 5.144234e-03 4.358774e-01
## 216 1 79 5.144234e-03 4.358774e-01
## 217 1 79 5.144234e-03 4.358774e-01
## 218 2 206 1.341408e-02 4.395821e-01
## 219 1 80 5.209351e-03 4.399613e-01
## 220 3 337 2.194439e-02 4.408760e-01
## 221 1 81 5.274468e-03 4.440158e-01
## 222 1 83 5.404701e-03 4.520378e-01
## 223 1 86 5.600052e-03 4.638562e-01
## 224 1 86 5.600052e-03 4.638562e-01
## 225 1 88 5.730286e-03 4.715944e-01
## 226 1 88 5.730286e-03 4.715944e-01
## 227 1 89 5.795403e-03 4.754219e-01
## 228 1 90 5.860520e-03 4.792220e-01
## 229 13 1728 1.125220e-01 4.831661e-01
## 230 1 92 5.990753e-03 4.867404e-01
## 231 1 92 5.990753e-03 4.867404e-01
## 232 2 226 1.471642e-02 4.873270e-01
## 233 1 97 6.316338e-03 5.050691e-01
## 234 1 99 6.446572e-03 5.122176e-01
## 235 7 933 6.075405e-02 5.150380e-01
## 236 1 100 6.511688e-03 5.157534e-01
## 237 1 100 6.511688e-03 5.157534e-01
## 238 1 106 6.902390e-03 5.364410e-01
## 239 1 107 6.967507e-03 5.398028e-01
## 240 1 110 7.162857e-03 5.497437e-01
## 241 2 256 1.666992e-02 5.540583e-01
## 242 6 828 5.391678e-02 5.562779e-01
## 243 1 115 7.488442e-03 5.658412e-01
## 244 3 412 2.682816e-02 5.748494e-01
## 245 1 118 7.683792e-03 5.752245e-01
## 246 1 119 7.748909e-03 5.783074e-01
## 247 1 130 8.465195e-03 6.107900e-01
## 248 13 1917 1.248291e-01 6.398173e-01
## 249 3 460 2.995377e-02 6.495505e-01
## 250 1 147 9.572182e-03 6.561776e-01
## 251 1 154 1.002800e-02 6.733045e-01
## 252 1 159 1.035358e-02 6.850177e-01
## 253 1 168 1.093964e-02 7.050621e-01
## 254 1 169 1.100475e-02 7.072097e-01
## 255 1 172 1.120010e-02 7.135600e-01
## 256 1 173 1.126522e-02 7.156462e-01
## 257 1 258 1.680016e-02 8.475105e-01
## 258 1 297 1.933971e-02 8.855639e-01
## 259 1 329 2.142346e-02 9.096303e-01
## 260 8 1637 1.065963e-01 9.152165e-01
## 261 1 339 2.207462e-02 9.160667e-01
## 262 1 380 2.474442e-02 9.380349e-01
## 263 1 385 2.507000e-02 9.402894e-01
## 264 1 398 2.591652e-02 9.457780e-01
## 265 1 431 2.806538e-02 9.575661e-01
## 266 1 490 3.190727e-02 9.726610e-01
## 267 1 547 3.561894e-02 9.821515e-01
## 268 9 2238 1.457316e-01 9.862116e-01
## 269 2 1033 6.726574e-02 9.960408e-01
## 270 2 1051 6.843785e-02 9.964993e-01
## 271 1 795 5.176792e-02 9.972614e-01
## 272 1 876 5.704239e-02 9.985255e-01
## 273 8 2661 1.732760e-01 9.994218e-01
## 274 1 1101 7.169369e-02 9.997407e-01
## 275 2 1463 9.526600e-02 9.998107e-01
## 276 6 2528 1.646155e-01 9.998952e-01
## 277 1 1262 8.217751e-02 9.999265e-01
## 278 1 1463 9.526600e-02 9.999851e-01
## 279 4 3662 2.384580e-01 1.000000e+00
## Entities.FDR X.Reactions.found X.Reactions.total Reactions.ratio
## 1 2.664535e-15 4 4 2.762049e-04
## 2 2.664535e-15 4 4 2.762049e-04
## 3 2.664535e-15 7 7 4.833587e-04
## 4 2.664535e-15 7 8 5.524099e-04
## 5 2.664535e-15 16 20 1.381025e-03
## 6 2.664535e-15 194 352 2.430604e-02
## 7 2.664535e-15 221 451 3.114211e-02
## 8 2.664535e-15 43 91 6.283662e-03
## 9 2.664535e-15 2 5 3.452562e-04
## 10 2.664535e-15 20 56 3.866869e-03
## 11 2.664535e-15 7 33 2.278691e-03
## 12 2.664535e-15 6 32 2.209640e-03
## 13 7.327472e-15 5 8 5.524099e-04
## 14 2.220446e-14 3 27 1.864383e-03
## 15 5.206058e-12 7 113 7.802790e-03
## 16 5.727618e-11 31 101 6.974175e-03
## 17 1.656685e-10 15 15 1.035769e-03
## 18 7.916592e-09 12 27 1.864383e-03
## 19 1.936653e-08 8 28 1.933435e-03
## 20 6.710359e-08 22 25 1.726281e-03
## 21 7.323014e-08 66 78 5.385996e-03
## 22 8.175711e-08 68 80 5.524099e-03
## 23 8.382314e-08 35 203 1.401740e-02
## 24 1.145939e-07 6 8 5.524099e-04
## 25 1.145939e-07 35 212 1.463886e-02
## 26 1.826805e-06 20 61 4.212125e-03
## 27 4.234569e-06 38 40 2.762049e-03
## 28 4.234569e-06 38 40 2.762049e-03
## 29 1.715723e-05 15 15 1.035769e-03
## 30 4.513092e-05 4 4 2.762049e-04
## 31 6.343847e-05 12 38 2.623947e-03
## 32 1.032080e-04 6 14 9.667173e-04
## 33 1.379140e-04 12 24 1.657230e-03
## 34 1.471307e-04 6 6 4.143074e-04
## 35 1.619713e-04 2 2 1.381025e-04
## 36 1.706599e-04 13 13 8.976661e-04
## 37 2.104439e-04 2 2 1.381025e-04
## 38 2.432271e-04 13 14 9.667173e-04
## 39 2.778212e-04 2 4 2.762049e-04
## 40 2.778212e-04 3 3 2.071537e-04
## 41 2.778212e-04 4 4 2.762049e-04
## 42 2.778212e-04 4 4 2.762049e-04
## 43 8.322232e-04 2 11 7.595636e-04
## 44 1.146079e-03 2 4 2.762049e-04
## 45 1.228583e-03 3 3 2.071537e-04
## 46 1.650929e-03 4 6 4.143074e-04
## 47 2.070817e-03 21 55 3.797818e-03
## 48 2.539502e-03 2 2 1.381025e-04
## 49 2.539502e-03 3 3 2.071537e-04
## 50 2.539502e-03 2 2 1.381025e-04
## 51 2.539502e-03 3 11 7.595636e-04
## 52 2.921115e-03 11 12 8.286148e-04
## 53 3.062511e-03 2 2 1.381025e-04
## 54 3.062511e-03 8 34 2.347742e-03
## 55 3.062511e-03 3 3 2.071537e-04
## 56 3.062511e-03 1 1 6.905124e-05
## 57 3.062511e-03 2 18 1.242922e-03
## 58 3.356621e-03 2 2 1.381025e-04
## 59 3.356621e-03 1 1 6.905124e-05
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## Species.identifier Species.name
## 1 9606 Homo sapiens
## 2 9606 Homo sapiens
## 3 9606 Homo sapiens
## 4 9606 Homo sapiens
## 5 9606 Homo sapiens
## 6 9606 Homo sapiens
## 7 9606 Homo sapiens
## 8 9606 Homo sapiens
## 9 9606 Homo sapiens
## 10 9606 Homo sapiens
## 11 9606 Homo sapiens
## 12 9606 Homo sapiens
## 13 9606 Homo sapiens
## 14 9606 Homo sapiens
## 15 9606 Homo sapiens
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## 17 9606 Homo sapiens
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## 19 9606 Homo sapiens
## 20 9606 Homo sapiens
## 21 9606 Homo sapiens
## 22 9606 Homo sapiens
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## 24 9606 Homo sapiens
## 25 9606 Homo sapiens
## 26 9606 Homo sapiens
## 27 9606 Homo sapiens
## 28 9606 Homo sapiens
## 29 9606 Homo sapiens
## 30 9606 Homo sapiens
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## 36 9606 Homo sapiens
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## 100 9606 Homo sapiens
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## 103 9606 Homo sapiens
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## 105 9606 Homo sapiens
## 106 9606 Homo sapiens
## 107 9606 Homo sapiens
## 108 9606 Homo sapiens
## 109 9606 Homo sapiens
## 110 9606 Homo sapiens
## 111 9606 Homo sapiens
## 112 9606 Homo sapiens
## 113 9606 Homo sapiens
## 114 9606 Homo sapiens
## 115 9606 Homo sapiens
## 116 9606 Homo sapiens
## 117 9606 Homo sapiens
## 118 9606 Homo sapiens
## 119 9606 Homo sapiens
## 120 9606 Homo sapiens
## 121 9606 Homo sapiens
## 122 9606 Homo sapiens
## 123 9606 Homo sapiens
## 124 9606 Homo sapiens
## 125 9606 Homo sapiens
## 126 9606 Homo sapiens
## 127 9606 Homo sapiens
## 128 9606 Homo sapiens
## 129 9606 Homo sapiens
## 130 9606 Homo sapiens
## 131 9606 Homo sapiens
## 132 9606 Homo sapiens
## 133 9606 Homo sapiens
## 134 9606 Homo sapiens
## 135 9606 Homo sapiens
## 136 9606 Homo sapiens
## 137 9606 Homo sapiens
## 138 9606 Homo sapiens
## 139 9606 Homo sapiens
## 140 9606 Homo sapiens
## 141 9606 Homo sapiens
## 142 9606 Homo sapiens
## 143 9606 Homo sapiens
## 144 9606 Homo sapiens
## 145 9606 Homo sapiens
## 146 9606 Homo sapiens
## 147 9606 Homo sapiens
## 148 9606 Homo sapiens
## 149 9606 Homo sapiens
## 150 9606 Homo sapiens
## 151 9606 Homo sapiens
## 152 9606 Homo sapiens
## 153 9606 Homo sapiens
## 154 9606 Homo sapiens
## 155 9606 Homo sapiens
## 156 9606 Homo sapiens
## 157 9606 Homo sapiens
## 158 9606 Homo sapiens
## 159 9606 Homo sapiens
## 160 9606 Homo sapiens
## 161 9606 Homo sapiens
## 162 9606 Homo sapiens
## 163 9606 Homo sapiens
## 164 9606 Homo sapiens
## 165 9606 Homo sapiens
## 166 9606 Homo sapiens
## 167 9606 Homo sapiens
## 168 9606 Homo sapiens
## 169 9606 Homo sapiens
## 170 9606 Homo sapiens
## 171 9606 Homo sapiens
## 172 9606 Homo sapiens
## 173 9606 Homo sapiens
## 174 9606 Homo sapiens
## 175 9606 Homo sapiens
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## 177 9606 Homo sapiens
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## 179 9606 Homo sapiens
## 180 9606 Homo sapiens
## 181 9606 Homo sapiens
## 182 9606 Homo sapiens
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## 184 9606 Homo sapiens
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## 186 9606 Homo sapiens
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## 188 9606 Homo sapiens
## 189 9606 Homo sapiens
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## 191 9606 Homo sapiens
## 192 9606 Homo sapiens
## 193 9606 Homo sapiens
## 194 9606 Homo sapiens
## 195 9606 Homo sapiens
## 196 9606 Homo sapiens
## 197 9606 Homo sapiens
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## 200 9606 Homo sapiens
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## 205 9606 Homo sapiens
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## 207 9606 Homo sapiens
## 208 9606 Homo sapiens
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## 212 9606 Homo sapiens
## 213 9606 Homo sapiens
## 214 9606 Homo sapiens
## 215 9606 Homo sapiens
## 216 9606 Homo sapiens
## 217 9606 Homo sapiens
## 218 9606 Homo sapiens
## 219 9606 Homo sapiens
## 220 9606 Homo sapiens
## 221 9606 Homo sapiens
## 222 9606 Homo sapiens
## 223 9606 Homo sapiens
## 224 9606 Homo sapiens
## 225 9606 Homo sapiens
## 226 9606 Homo sapiens
## 227 9606 Homo sapiens
## 228 9606 Homo sapiens
## 229 9606 Homo sapiens
## 230 9606 Homo sapiens
## 231 9606 Homo sapiens
## 232 9606 Homo sapiens
## 233 9606 Homo sapiens
## 234 9606 Homo sapiens
## 235 9606 Homo sapiens
## 236 9606 Homo sapiens
## 237 9606 Homo sapiens
## 238 9606 Homo sapiens
## 239 9606 Homo sapiens
## 240 9606 Homo sapiens
## 241 9606 Homo sapiens
## 242 9606 Homo sapiens
## 243 9606 Homo sapiens
## 244 9606 Homo sapiens
## 245 9606 Homo sapiens
## 246 9606 Homo sapiens
## 247 9606 Homo sapiens
## 248 9606 Homo sapiens
## 249 9606 Homo sapiens
## 250 9606 Homo sapiens
## 251 9606 Homo sapiens
## 252 9606 Homo sapiens
## 253 9606 Homo sapiens
## 254 9606 Homo sapiens
## 255 9606 Homo sapiens
## 256 9606 Homo sapiens
## 257 9606 Homo sapiens
## 258 9606 Homo sapiens
## 259 9606 Homo sapiens
## 260 9606 Homo sapiens
## 261 9606 Homo sapiens
## 262 9606 Homo sapiens
## 263 9606 Homo sapiens
## 264 9606 Homo sapiens
## 265 9606 Homo sapiens
## 266 9606 Homo sapiens
## 267 9606 Homo sapiens
## 268 9606 Homo sapiens
## 269 9606 Homo sapiens
## 270 9606 Homo sapiens
## 271 9606 Homo sapiens
## 272 9606 Homo sapiens
## 273 9606 Homo sapiens
## 274 9606 Homo sapiens
## 275 9606 Homo sapiens
## 276 9606 Homo sapiens
## 277 9606 Homo sapiens
## 278 9606 Homo sapiens
## 279 9606 Homo sapiens
## Submitted.entities.found
## 1 CENPU;ERCC6L;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 2 CENPU;ERCC6L;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 3 CENPU;ERCC6L;UBE2C;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 4 CENPU;ERCC6L;CDCA5;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;CCNB2;KIF18A;SGOL1;CENPI;NUF2;CDK1;KIF2C;BUB1;SPC25
## 5 CENPU;ERCC6L;CDCA5;PLK1;NCAPG;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;NCAPH;CDC20;CCNB2;KIF18A;SGOL1;CENPI;NUF2;CDK1;KIF2C;NEK2;BUB1;SPC25
## 6 TOP2A;ERCC6L;CDCA5;NCAPG;BUB1B;CDCA8;FOXM1;PKMYT1;CENPA;NCAPH;AURKB;CDC20;CCNB2;ORC6;CDC45;SGOL1;NUF2;NEK2;MYBL2;TK1;BUB1;GTSE1;GINS1;CENPU;BORA;RRM2;UBE2C;PLK1;KIF23;ESCO2;MASTL;CDC25C;NDC80;ZWINT;CCNA2;KIF18A;CENPI;CDK1;KIF2C;KIF20A;SPC25
## 7 TOP2A;PIF1;ERCC6L;CDCA5;DSCC1;HJURP;NCAPG;BUB1B;CDCA8;BRCA2;FOXM1;PKMYT1;CENPA;NCAPH;AURKB;CDC20;CCNB2;ORC6;CDC45;SGOL1;EXO1;NUF2;OIP5;NEK2;MYBL2;TK1;BUB1;GTSE1;GINS1;CENPU;BORA;RRM2;UBE2C;PLK1;MND1;KIF23;ESCO2;MASTL;CDC25C;NDC80;ZWINT;CCNA2;KIF18A;CENPI;CDK1;KIF2C;KIF20A;SPC25
## 8 ERCC6L;CDCA5;CDCA8;NCAPG;BUB1B;CENPA;AURKB;NCAPH;CDC20;CCNB2;SGOL1;NUF2;NEK2;BUB1;CENPU;UBE2C;PLK1;KIF23;MASTL;NDC80;ZWINT;KIF18A;CENPI;CDK1;KIF2C;KIF20A;SPC25
## 9 CENPU;ERCC6L;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 10 ERCC6L;CDCA8;BUB1B;PKMYT1;CENPA;AURKB;CDC20;CCNB2;ORC6;CDC45;SGOL1;EXO1;NUF2;BUB1;GTSE1;CENPU;UBE2C;PLK1;CDC25C;NDC80;ZWINT;CCNA2;KIF18A;CENPI;CDK1;KIF2C;SPC25
## 11 CENPU;ERCC6L;UBE2C;CDCA5;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;CCNB2;KIF18A;SGOL1;CENPI;NUF2;CDK1;KIF2C;BUB1;SPC25
## 12 CENPU;ERCC6L;UBE2C;CDCA5;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;CCNB2;KIF18A;SGOL1;CENPI;NUF2;CDK1;KIF2C;BUB1;SPC25
## 13 CENPU;ERCC6L;UBE2C;CDCA5;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 14 CENPU;ERCC6L;PLK1;BUB1B;CDCA8;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;NUF2;KIF2C;BUB1;SPC25
## 15 CENPU;ERCC6L;PLK1;KIF14;BUB1B;CDCA8;CDC25C;CENPA;AURKB;NDC80;ZWINT;CDC20;KIF18A;SGOL1;CENPI;PRC1;NUF2;KIF2C;BUB1;SPC25
## 16 TOP2A;CCNA2;RRM2;ORC6;CDC45;CDK1;MYBL2;TK1
## 17 CCNB2;PLK1;MYBL2;FOXM1;CDC25C;PKMYT1
## 18 CCNA2;TOP2A;CDK1;MYBL2
## 19 RRM2;CDC45;CDK1;TK1
## 20 CCNA2;CCNB2;PLK1;CDK1;FOXM1;CDC25C;PKMYT1
## 21 CCNA2;CCNB2;BORA;PLK1;CDK1;NEK2;MYBL2;FOXM1;CDC25C;PKMYT1;GTSE1
## 22 CCNA2;CCNB2;BORA;PLK1;CDK1;NEK2;MYBL2;FOXM1;CDC25C;PKMYT1;GTSE1
## 23 CENPU;ERCC6L;ARHGEF39;PLK1;KIF14;BUB1B;CDCA8;CDC25C;CENPA;AURKB;NDC80;ZWINT;CDC20;DEPDC1B;KIF18A;SGOL1;CENPI;PRC1;NUF2;KIF2C;BUB1;SPC25
## 24 CCNA2;CDK1;MYBL2
## 25 CENPU;ERCC6L;ARHGEF39;PLK1;KIF14;BUB1B;CDCA8;CDC25C;CENPA;AURKB;NDC80;ZWINT;CDC20;DEPDC1B;KIF18A;SGOL1;CENPI;PRC1;NUF2;KIF2C;BUB1;SPC25
## 26 CCNA2;RRM2;ORC6;CDC45;CDK1;TK1
## 27 CDC20;CCNA2;UBE2C;PLK1;CDK1;BUB1B;NEK2;BUB1;AURKB
## 28 CDC20;CCNA2;UBE2C;PLK1;CDK1;BUB1B;NEK2;BUB1;AURKB
## 29 CDC20;CCNA2;UBE2C;PLK1;CDK1;BUB1B;NEK2;BUB1
## 30 CCNB2;CDK1;NCAPG;NCAPH
## 31 CCNA2;CENPU;PIF1;CENPI;DSCC1;HJURP;OIP5;CENPA
## 32 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 33 CCNB2;ORC6;CDC45;EXO1;CDK1;CDC25C;PKMYT1;GTSE1
## 34 CDC20;CCNA2;UBE2C;CDK1;BUB1B;NEK2;BUB1
## 35 CCNB2;CDK1;PKMYT1
## 36 CDC20;CCNA2;UBE2C;CDK1;BUB1B;NEK2;BUB1
## 37 CDC20;PLK1;CDK1
## 38 CDC20;CCNA2;UBE2C;PLK1;CDK1;BUB1B;BUB1
## 39 CCNB2;PLK1;CDK1
## 40 CDC20;UBE2C;BUB1B;NEK2;BUB1
## 41 CENPU;CENPI;HJURP;OIP5;CENPA
## 42 CENPU;CENPI;HJURP;OIP5;CENPA
## 43 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 44 PLK1;KIF23;KIF20A
## 45 CDC20;CCNA2;UBE2C;CDK1;BUB1B;BUB1
## 46 CCNB2;PLK1;CDK1
## 47 GINS1;CCNA2;ORC6;CDC45;UBE2C;CDCA5;ESCO2
## 48 UBE2C;PLK1;CDK1
## 49 CDC20;UBE2C;BUB1B;BUB1
## 50 CDC20;UBE2C;BUB1B;BUB1
## 51 CDK1;CDC25C
## 52 CCNB2;BORA;PLK1;CDK1;NEK2
## 53 CCNA2;CDK1
## 54 RAD51AP1;NEIL3;EXO1;BRCA2
## 55 CDC20;UBE2C;CDK1
## 56 RAD51AP1;EXO1;BRCA2
## 57 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 58 RAD51AP1;EXO1;BRCA2
## 59 RAD51AP1;EXO1;BRCA2
## 60 RAD51AP1;EXO1;BRCA2
## 61 RAD51AP1;EXO1;BRCA2
## 62 CCNA2;CDK1;CDC25C
## 63 RAD51AP1;EXO1;BRCA2
## 64 ORC6;CDK1
## 65 MYBL2
## 66 CDC20;UBE2C;PLK1;AURKB
## 67 RAD51AP1;EXO1;BRCA2
## 68 RAD51AP1;EXO1;BRCA2
## 69 GINS1;CCNA2;ORC6;CDC45;UBE2C
## 70 ORC6;CDC45;CDC25C
## 71 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 72 CCNB2;PLK1;CDK1;GTSE1
## 73 RAD51AP1;EXO1;BRCA2
## 74 RAD51AP1;EXO1;BRCA2
## 75 CDK1;MASTL
## 76 GINS1;CDC45
## 77 CDCA5;ESCO2
## 78 RAD51AP1;EXO1;BRCA2
## 79 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 80 CDK1;CDC25C
## 81 TOP2A;CDCA8;AURKB
## 82 NEIL3
## 83 NEIL3
## 84 GINS1;CCNA2;ORC6;CDC45;UBE2C
## 85 CDC20;UBE2C
## 86 CCNB2;PLK1;CDK1
## 87 PRC1;KIF14
## 88 RAD51AP1;CCNA2;EXO1;BRCA2
## 89 CCNA2;PIF1;DSCC1
## 90 ORC6;CDK1
## 91 BRCA2
## 92 BRCA2
## 93 TOP2A
## 94 RAD51AP1;CCNA2;EXO1;BRCA2
## 95 PLK1;CDK1;NEK2
## 96 PLK1;CDK1;NEK2
## 97 RAD51AP1;EXO1;BRCA2
## 98 CCNB2;PLK1;CDK1;MASTL
## 99 CCNB2;CDK1
## 100 PLK1;CDK1;NEK2
## 101 KIF18A;KIF23;KIF2C;KIF20A
## 102 EXO1;CDK1;CDC25C
## 103 PLK1;CDK1;NEK2
## 104 PLK1;CDK1;NEK2
## 105 CCNA2;PIF1
## 106 EXO1;BRCA2
## 107 ORC6;CDC45
## 108 PLK1
## 109 CCNA2;ORC6;UBE2C
## 110 GINS1;CDC45
## 111 CCNA2;EXO1;AURKB
## 112 PLK1;CDK1;NEK2
## 113 RAD51AP1;CCNA2;EXO1;BRCA2
## 114 PLK1;CDK1;NEK2
## 115 EXO1;BRCA2
## 116 CCNB2;CDK1
## 117 DEPDC1B;KIF14
## 118 CCNA2;CDK1
## 119 CCNA2;EXO1;CDK1;AURKB
## 120 DEPDC1B;KIF14
## 121 CCNA2;PIF1;DSCC1
## 122 RRM2
## 123 CCNA2;CDK1
## 124 CCNA2
## 125 MYBL2
## 126 ORC6
## 127 NEIL3
## 128 PLK1;CDK1
## 129 PTGS1
## 130 MND1;BRCA2
## 131 PRR11
## 132 ORC6;CDC45;UBE2C
## 133 CDC20;UBE2C
## 134 CDK1
## 135 CCNA2;ORC6
## 136 CCNA2;UBE2C
## 137 BRCA2
## 138 PRR11
## 139 CCNB2;CDK1
## 140 UBE2C
## 141 CCNA2
## 142 CCNA2;EXO1
## 143 CCNA2;UBE2C
## 144 CCNA2;EXO1;CDK1;CDC25C;AURKB
## 145 MND1;BRCA2
## 146 RAD51AP1;CCNA2;NEIL3;EXO1;BRCA2
## 147 EXO1
## 148 EXO1
## 149 SPC25
## 150 TOP2A;CDCA8;AURKB
## 151 CDK1
## 152 EXO1
## 153 TOP2A;CDCA8;AURKB
## 154 SPC25
## 155 CDK1
## 156 CDC25C
## 157 TACC3
## 158 PLK1;CDK1;NEK2
## 159 CDC25C
## 160 CDC25C
## 161 ORC6;UBE2C
## 162 DSCC1
## 163 UBE2C
## 164 CDC25C
## 165 TK1
## 166 PRR11
## 167 UBE2C
## 168 NEIL3
## 169 UBE2C
## 170 EXO1
## 171 DEPDC1B
## 172 ORC6
## 173 AURKB
## 174 NEIL3
## 175 LCE1B;LCE1E
## 176 DEPDC1B
## 177 NEIL3
## 178 DEPDC1B
## 179 CDK1
## 180 NEIL3
## 181 MND1;BRCA2
## 182 DEPDC1B
## 183 SPC25
## 184 UBE2C
## 185 DSCC1
## 186 NEIL3
## 187 NEIL3
## 188 SPC25
## 189 CDC20
## 190 TACC3
## 191 DEPDC1B
## 192 PTGS1
## 193 CENPU;ERCC6L;ARHGEF39;PLK1;KIF14;CDCA8;BUB1B;CDC25C;CENPA;NDC80;AURKB;ZWINT;CDC20;KIF18A;DEPDC1B;SGOL1;CENPI;PRC1;NUF2;TACC3;CDK1;KIF2C;BUB1;SPC25
## 194 CDC20;CCNA2;CDK1
## 195 DEPDC1B
## 196 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 197 CCNA2;RRM2;UBE2C;EXO1;ZNF724P;CDK1;MYBL2;CDC25C;AURKB;CEP55
## 198 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A;PRR11
## 199 CCNA2
## 200 NEIL3
## 201 DEPDC1B
## 202 TACC3
## 203 UBE2C
## 204 ARHGEF39
## 205 TK1
## 206 CCNA2
## 207 CCNA2
## 208 CCNA2
## 209 CDC20;UBE2C;TRAIP
## 210 DEPDC1B;ARHGEF39
## 211 CCNA2
## 212 DEPDC1B
## 213 CCNA2;UBE2C
## 214 DEPDC1B
## 215 DEPDC1B
## 216 CDC25C
## 217 AKR1B10
## 218 CDC20;CCNA2
## 219 RRM2
## 220 PLK1;CDK1;NEK2
## 221 ARHGEF39
## 222 UBE2C
## 223 CEP55
## 224 ARHGEF39
## 225 CCNA2
## 226 CDK1
## 227 AKR1B10
## 228 CCNA2
## 229 CCNA2;RRM2;UBE2C;EXO1;ZNF724P;CDK1;MYBL2;CDC25C;AURKB;CEP55
## 230 DEPDC1B
## 231 TACC3
## 232 LCE1B;LCE1E
## 233 CDC25C
## 234 NEIL3
## 235 CDC20;KIF18A;UBE2C;KIF23;KIF2C;KIF20A;TRAIP
## 236 DEPDC1B
## 237 AURKB
## 238 CDK1
## 239 PRR11
## 240 ARHGEF39
## 241 RRM2;TK1
## 242 KIF18A;KIF18B;KIFC1;KIF23;KIF2C;KIF20A
## 243 LY6D
## 244 CDC20;UBE2C;TRAIP
## 245 PRR11
## 246 SPC25
## 247 SPC25
## 248 CCNA2;RRM2;UBE2C;EXO1;ZNF724P;CDK1;MYBL2;CDC25C;AURKB;CEP55
## 249 DEPDC1B;ARHGEF39;KIF14
## 250 CDK1
## 251 DEPDC1B
## 252 DEPDC1B
## 253 PTGS1
## 254 AKR1B10
## 255 ARHGEF39
## 256 CDK1
## 257 TACC3
## 258 PTGS1
## 259 CDK1
## 260 CDC20;TOP2A;CCNA2;UBE2C;CDK1;LY6D;CDCA8;AURKB
## 261 SPC25
## 262 CDK1
## 263 AKR1B10
## 264 CDK1
## 265 PTGS1
## 266 PRR11
## 267 PTGS1
## 268 CDC20;TOP2A;CCNA2;UBE2C;CDK1;LY6D;CDCA8;AURKB;SPC25
## 269 CCNA2;UBE2C
## 270 CCNA2;UBE2C
## 271 ARHGEF39
## 272 ARHGEF39
## 273 CDC20;KIF18A;UBE2C;CDK1;KIF23;KIF2C;KIF20A;TRAIP
## 274 CDK1
## 275 LCE1B;LCE1E
## 276 RAD51AP1;NEIL3;UBE2C;EXO1;CDC25C;BRCA2
## 277 AKR1B10
## 278 PTGS1
## 279 RRM2;AKR1B10;TK1;PTGS1
## Mapped.entities
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 NA
## 6 NA
## 7 NA
## 8 NA
## 9 NA
## 10 NA
## 11 NA
## 12 NA
## 13 NA
## 14 NA
## 15 NA
## 16 NA
## 17 NA
## 18 NA
## 19 NA
## 20 NA
## 21 NA
## 22 NA
## 23 NA
## 24 NA
## 25 NA
## 26 NA
## 27 NA
## 28 NA
## 29 NA
## 30 NA
## 31 NA
## 32 NA
## 33 NA
## 34 NA
## 35 NA
## 36 NA
## 37 NA
## 38 NA
## 39 NA
## 40 NA
## 41 NA
## 42 NA
## 43 NA
## 44 NA
## 45 NA
## 46 NA
## 47 NA
## 48 NA
## 49 NA
## 50 NA
## 51 NA
## 52 NA
## 53 NA
## 54 NA
## 55 NA
## 56 NA
## 57 NA
## 58 NA
## 59 NA
## 60 NA
## 61 NA
## 62 NA
## 63 NA
## 64 NA
## 65 NA
## 66 NA
## 67 NA
## 68 NA
## 69 NA
## 70 NA
## 71 NA
## 72 NA
## 73 NA
## 74 NA
## 75 NA
## 76 NA
## 77 NA
## 78 NA
## 79 NA
## 80 NA
## 81 NA
## 82 NA
## 83 NA
## 84 NA
## 85 NA
## 86 NA
## 87 NA
## 88 NA
## 89 NA
## 90 NA
## 91 NA
## 92 NA
## 93 NA
## 94 NA
## 95 NA
## 96 NA
## 97 NA
## 98 NA
## 99 NA
## 100 NA
## 101 NA
## 102 NA
## 103 NA
## 104 NA
## 105 NA
## 106 NA
## 107 NA
## 108 NA
## 109 NA
## 110 NA
## 111 NA
## 112 NA
## 113 NA
## 114 NA
## 115 NA
## 116 NA
## 117 NA
## 118 NA
## 119 NA
## 120 NA
## 121 NA
## 122 NA
## 123 NA
## 124 NA
## 125 NA
## 126 NA
## 127 NA
## 128 NA
## 129 NA
## 130 NA
## 131 NA
## 132 NA
## 133 NA
## 134 NA
## 135 NA
## 136 NA
## 137 NA
## 138 NA
## 139 NA
## 140 NA
## 141 NA
## 142 NA
## 143 NA
## 144 NA
## 145 NA
## 146 NA
## 147 NA
## 148 NA
## 149 NA
## 150 NA
## 151 NA
## 152 NA
## 153 NA
## 154 NA
## 155 NA
## 156 NA
## 157 NA
## 158 NA
## 159 NA
## 160 NA
## 161 NA
## 162 NA
## 163 NA
## 164 NA
## 165 NA
## 166 NA
## 167 NA
## 168 NA
## 169 NA
## 170 NA
## 171 NA
## 172 NA
## 173 NA
## 174 NA
## 175 NA
## 176 NA
## 177 NA
## 178 NA
## 179 NA
## 180 NA
## 181 NA
## 182 NA
## 183 NA
## 184 NA
## 185 NA
## 186 NA
## 187 NA
## 188 NA
## 189 NA
## 190 NA
## 191 NA
## 192 NA
## 193 NA
## 194 NA
## 195 NA
## 196 NA
## 197 NA
## 198 NA
## 199 NA
## 200 NA
## 201 NA
## 202 NA
## 203 NA
## 204 NA
## 205 NA
## 206 NA
## 207 NA
## 208 NA
## 209 NA
## 210 NA
## 211 NA
## 212 NA
## 213 NA
## 214 NA
## 215 NA
## 216 NA
## 217 NA
## 218 NA
## 219 NA
## 220 NA
## 221 NA
## 222 NA
## 223 NA
## 224 NA
## 225 NA
## 226 NA
## 227 NA
## 228 NA
## 229 NA
## 230 NA
## 231 NA
## 232 NA
## 233 NA
## 234 NA
## 235 NA
## 236 NA
## 237 NA
## 238 NA
## 239 NA
## 240 NA
## 241 NA
## 242 NA
## 243 NA
## 244 NA
## 245 NA
## 246 NA
## 247 NA
## 248 NA
## 249 NA
## 250 NA
## 251 NA
## 252 NA
## 253 NA
## 254 NA
## 255 NA
## 256 NA
## 257 NA
## 258 NA
## 259 NA
## 260 NA
## 261 NA
## 262 NA
## 263 NA
## 264 NA
## 265 NA
## 266 NA
## 267 NA
## 268 NA
## 269 NA
## 270 NA
## 271 NA
## 272 NA
## 273 NA
## 274 NA
## 275 NA
## 276 NA
## 277 NA
## 278 NA
## 279 NA
## Found.reaction.identifiers
## 1 R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439
## 2 R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439
## 3 R-HSA-141409;R-HSA-141431;R-HSA-141429;R-HSA-141422;R-HSA-141439;R-HSA-141423;R-HSA-141437
## 4 R-HSA-2468293;R-HSA-2466068;R-HSA-2484822;R-HSA-2467794;R-HSA-2468287;R-HSA-1638803;R-HSA-1638821
## 5 R-HSA-2514854;R-HSA-2468293;R-HSA-9648114;R-HSA-375302;R-HSA-156682;R-HSA-1638803;R-HSA-2529015;R-HSA-2466068;R-HSA-2484822;R-HSA-2520883;R-HSA-2467794;R-HSA-380316;R-HSA-380508;R-HSA-2468287;R-HSA-2529020;R-HSA-1638821
## 6 R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-156682;R-HSA-174088;R-HSA-187916;R-HSA-156699;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-380455;R-HSA-3000335;R-HSA-187937;R-HSA-174119;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-170044;R-HSA-3000339;R-HSA-2245218;R-HSA-174144;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-174159;R-HSA-174157;R-HSA-170070;R-HSA-174164;R-HSA-380508;R-HSA-174171;R-HSA-170072;R-HSA-174174;R-HSA-170076;R-HSA-2430533;R-HSA-2430535;R-HSA-170087;R-HSA-170084;R-HSA-170088;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-69754;R-HSA-69756;R-HSA-141437;R-HSA-187520;R-HSA-174209;R-HSA-170116;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-174235;R-HSA-2473151;R-HSA-174238;R-HSA-187552;R-HSA-170149;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-5244669;R-HSA-174255;R-HSA-170159;R-HSA-170156;R-HSA-170161;R-HSA-4086410;R-HSA-187574;R-HSA-187575;R-HSA-163010;R-HSA-174273;R-HSA-5195402;R-HSA-179410;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-179421;R-HSA-2468039;R-HSA-2473152;R-HSA-4088024;R-HSA-2468041;R-HSA-2172194;R-HSA-8852354;R-HSA-8961934;R-HSA-8961920;R-HSA-2294574;R-HSA-8852362;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-2294580;R-HSA-8853405;R-HSA-2294590;R-HSA-188191;R-HSA-9686969;R-HSA-8853419;R-HSA-176942;R-HSA-2168079;R-HSA-2984220;R-HSA-2466068;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2172183;R-HSA-68919;R-HSA-8961982;R-HSA-68918;R-HSA-8964531;R-HSA-8961972;R-HSA-176956;R-HSA-68940;R-HSA-8961991;R-HSA-68944;R-HSA-9686980;R-HSA-8964561;R-HSA-4088162;R-HSA-8964567;R-HSA-9648114;R-HSA-68960;R-HSA-162657;R-HSA-8964588;R-HSA-2314566;R-HSA-1363314;R-HSA-4088152;R-HSA-8978926;R-HSA-2294600;R-HSA-8964580;R-HSA-380278;R-HSA-1363303;R-HSA-4088141;R-HSA-380272;R-HSA-4088134;R-HSA-1363311;R-HSA-4088130;R-HSA-380283;R-HSA-1363306;R-HSA-8962039;R-HSA-2514854;R-HSA-380294;R-HSA-3002798;R-HSA-380303;R-HSA-1638803;R-HSA-69005;R-HSA-380311;R-HSA-3002811;R-HSA-69015;R-HSA-380316;R-HSA-2468287;R-HSA-1638821;R-HSA-8852280;R-HSA-2467809;R-HSA-2467811;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-188371;R-HSA-3000319;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-8852317;R-HSA-3000310;R-HSA-2574840;R-HSA-2468293;R-HSA-8852324;R-HSA-174054;R-HSA-113638;R-HSA-174058;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-8961915;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-2467794;R-HSA-8852351;R-HSA-2562526;R-HSA-8961907;R-HSA-174079
## 7 R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-156682;R-HSA-174088;R-HSA-187916;R-HSA-156699;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-75809;R-HSA-912429;R-HSA-380455;R-HSA-3000335;R-HSA-187937;R-HSA-174119;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-170044;R-HSA-3000339;R-HSA-2245218;R-HSA-174144;R-HSA-170055;R-HSA-606287;R-HSA-912458;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-174159;R-HSA-174157;R-HSA-170070;R-HSA-174164;R-HSA-606289;R-HSA-380508;R-HSA-174171;R-HSA-170072;R-HSA-174174;R-HSA-170076;R-HSA-2430533;R-HSA-2430535;R-HSA-141409;R-HSA-170087;R-HSA-170084;R-HSA-170088;R-HSA-141422;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-141431;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-912503;R-HSA-69754;R-HSA-69756;R-HSA-141439;R-HSA-912496;R-HSA-606326;R-HSA-141437;R-HSA-187520;R-HSA-174209;R-HSA-606349;R-HSA-170116;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-174235;R-HSA-2473151;R-HSA-174238;R-HSA-187552;R-HSA-170149;R-HSA-176298;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-5244669;R-HSA-174255;R-HSA-170159;R-HSA-170156;R-HSA-170161;R-HSA-4086410;R-HSA-187574;R-HSA-187575;R-HSA-176318;R-HSA-163010;R-HSA-174273;R-HSA-5195402;R-HSA-179410;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-179421;R-HSA-2468039;R-HSA-2473152;R-HSA-4088024;R-HSA-2468041;R-HSA-75010;R-HSA-2172194;R-HSA-8852354;R-HSA-8961934;R-HSA-8961920;R-HSA-75016;R-HSA-2294574;R-HSA-8852362;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-2294580;R-HSA-8853405;R-HSA-163096;R-HSA-2294590;R-HSA-188191;R-HSA-9686969;R-HSA-8853419;R-HSA-176942;R-HSA-2168079;R-HSA-2984220;R-HSA-2466068;R-HSA-163120;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2172183;R-HSA-68919;R-HSA-8961982;R-HSA-68918;R-HSA-8964531;R-HSA-8961972;R-HSA-176956;R-HSA-68940;R-HSA-8961991;R-HSA-68944;R-HSA-9686980;R-HSA-8964561;R-HSA-4088162;R-HSA-8964567;R-HSA-9648114;R-HSA-68960;R-HSA-162657;R-HSA-8964588;R-HSA-2314566;R-HSA-174439;R-HSA-1363314;R-HSA-4088152;R-HSA-8978926;R-HSA-9686521;R-HSA-2294600;R-HSA-8964580;R-HSA-174447;R-HSA-380278;R-HSA-1363303;R-HSA-4088141;R-HSA-380272;R-HSA-174452;R-HSA-4088134;R-HSA-1363311;R-HSA-4088130;R-HSA-380283;R-HSA-1363306;R-HSA-8962039;R-HSA-2514854;R-HSA-380294;R-HSA-3002798;R-HSA-6799332;R-HSA-380303;R-HSA-1638803;R-HSA-69005;R-HSA-380311;R-HSA-3002811;R-HSA-69015;R-HSA-380316;R-HSA-2468287;R-HSA-9668902;R-HSA-9668904;R-HSA-1638821;R-HSA-8852280;R-HSA-2467809;R-HSA-2467811;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-188371;R-HSA-3000319;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-8852317;R-HSA-3000310;R-HSA-2574840;R-HSA-2468293;R-HSA-8852324;R-HSA-174054;R-HSA-113638;R-HSA-174058;R-HSA-9029987;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-8961915;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-2467794;R-HSA-8852351;R-HSA-2562526;R-HSA-8961907;R-HSA-174079
## 8 R-HSA-2514854;R-HSA-2245218;R-HSA-163010;R-HSA-174144;R-HSA-375302;R-HSA-2172194;R-HSA-156673;R-HSA-2467809;R-HSA-5195402;R-HSA-2467811;R-HSA-156682;R-HSA-1638803;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2529015;R-HSA-2520883;R-HSA-2294580;R-HSA-380316;R-HSA-380508;R-HSA-2468287;R-HSA-2529020;R-HSA-2294590;R-HSA-2468293;R-HSA-2430533;R-HSA-9648114;R-HSA-2430535;R-HSA-2314566;R-HSA-2294600;R-HSA-174121;R-HSA-5244669;R-HSA-2168079;R-HSA-2214351;R-HSA-2984220;R-HSA-156723;R-HSA-2466068;R-HSA-9624800;R-HSA-380278;R-HSA-2484822;R-HSA-2172183;R-HSA-2467794;R-HSA-174202;R-HSA-1638821
## 9 R-HSA-9648114;R-HSA-156682
## 10 R-HSA-75809;R-HSA-141409;R-HSA-75010;R-HSA-6799332;R-HSA-170055;R-HSA-8852354;R-HSA-176298;R-HSA-75016;R-HSA-9029987;R-HSA-141422;R-HSA-141423;R-HSA-170070;R-HSA-141431;R-HSA-8852337;R-HSA-141429;R-HSA-8852351;R-HSA-187934;R-HSA-176318;R-HSA-141439;R-HSA-141437
## 11 R-HSA-163010;R-HSA-9624800;R-HSA-174144;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121
## 12 R-HSA-9624800;R-HSA-174144;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121
## 13 R-HSA-174144;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121
## 14 R-HSA-5666160;R-HSA-5666129;R-HSA-5666169
## 15 R-HSA-5671749;R-HSA-5671970;R-HSA-5666160;R-HSA-5666129;R-HSA-75016;R-HSA-5666169;R-HSA-5671737
## 16 R-HSA-187520;R-HSA-8961934;R-HSA-8961920;R-HSA-68940;R-HSA-8961991;R-HSA-8964561;R-HSA-8964567;R-HSA-68960;R-HSA-187552;R-HSA-8964588;R-HSA-1363314;R-HSA-113638;R-HSA-8978926;R-HSA-8964580;R-HSA-1363303;R-HSA-68914;R-HSA-8961915;R-HSA-8964475;R-HSA-187574;R-HSA-68917;R-HSA-187575;R-HSA-68916;R-HSA-68919;R-HSA-8961982;R-HSA-68918;R-HSA-8964531;R-HSA-1363311;R-HSA-8961907;R-HSA-8961972;R-HSA-1363306;R-HSA-8962039
## 17 R-HSA-162657;R-HSA-156678;R-HSA-4088152;R-HSA-4088441;R-HSA-4088439;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-4088305;R-HSA-4088298;R-HSA-4088299;R-HSA-4088134;R-HSA-156699;R-HSA-4088130;R-HSA-4088162
## 18 R-HSA-1363303;R-HSA-8964475;R-HSA-8964588;R-HSA-8961934;R-HSA-1363314;R-HSA-8978926;R-HSA-8964561;R-HSA-8964531;R-HSA-1363311;R-HSA-8964580;R-HSA-1363306;R-HSA-8964567
## 19 R-HSA-8961915;R-HSA-8961934;R-HSA-8961982;R-HSA-8961920;R-HSA-8961907;R-HSA-8961972;R-HSA-8962039;R-HSA-8961991
## 20 R-HSA-170087;R-HSA-170055;R-HSA-170116;R-HSA-170084;R-HSA-4088024;R-HSA-170149;R-HSA-170088;R-HSA-170057;R-HSA-170153;R-HSA-170158;R-HSA-170126;R-HSA-170159;R-HSA-170156;R-HSA-170131;R-HSA-170161;R-HSA-4088141;R-HSA-170070;R-HSA-170072;R-HSA-69754;R-HSA-69756;R-HSA-170076;R-HSA-170044
## 21 R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-380455;R-HSA-3000335;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-170161;R-HSA-4086410;R-HSA-170044;R-HSA-3000339;R-HSA-8852280;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-170072;R-HSA-8852317;R-HSA-3000310;R-HSA-4088162;R-HSA-170076;R-HSA-2574840;R-HSA-8852324;R-HSA-162657;R-HSA-170087;R-HSA-170084;R-HSA-4088024;R-HSA-4088152;R-HSA-170088;R-HSA-8852331;R-HSA-4088141;R-HSA-380272;R-HSA-8852337;R-HSA-4088134;R-HSA-8852351;R-HSA-2562526;R-HSA-69754;R-HSA-4088130;R-HSA-69756;R-HSA-380283
## 22 R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-380455;R-HSA-3000335;R-HSA-187937;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-170161;R-HSA-4086410;R-HSA-187959;R-HSA-170044;R-HSA-3000339;R-HSA-8852280;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-170072;R-HSA-8852317;R-HSA-3000310;R-HSA-4088162;R-HSA-170076;R-HSA-2574840;R-HSA-8852324;R-HSA-162657;R-HSA-170087;R-HSA-170084;R-HSA-4088024;R-HSA-4088152;R-HSA-170088;R-HSA-8852331;R-HSA-4088141;R-HSA-380272;R-HSA-8852337;R-HSA-4088134;R-HSA-8852351;R-HSA-2562526;R-HSA-69754;R-HSA-4088130;R-HSA-69756;R-HSA-380283
## 23 R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-5671749;R-HSA-9013022;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-9696271;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-5666160;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-5666169;R-HSA-5671737;R-HSA-9018745;R-HSA-9018808;R-HSA-9693282;R-HSA-9018746;R-HSA-9013437;R-HSA-5671970;R-HSA-9014449;R-HSA-9013111;R-HSA-9018806;R-HSA-9013110
## 24 R-HSA-8964588;R-HSA-8961934;R-HSA-8978926;R-HSA-8964561;R-HSA-8964580;R-HSA-8964567
## 25 R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-5671749;R-HSA-9013022;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-9696271;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-5666160;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-5666169;R-HSA-5671737;R-HSA-9018745;R-HSA-9018808;R-HSA-9693282;R-HSA-9018746;R-HSA-9013437;R-HSA-5671970;R-HSA-9014449;R-HSA-9013111;R-HSA-9018806;R-HSA-9013110
## 26 R-HSA-68960;R-HSA-187552;R-HSA-187520;R-HSA-8961934;R-HSA-113638;R-HSA-8961920;R-HSA-68940;R-HSA-8961991;R-HSA-68914;R-HSA-8961915;R-HSA-187574;R-HSA-68917;R-HSA-187575;R-HSA-68916;R-HSA-68919;R-HSA-8961982;R-HSA-68918;R-HSA-8961907;R-HSA-8961972;R-HSA-8962039
## 27 R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174122;R-HSA-174058;R-HSA-174251;R-HSA-174120;R-HSA-9686969;R-HSA-174057;R-HSA-174121;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437
## 28 R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174122;R-HSA-174058;R-HSA-174251;R-HSA-174120;R-HSA-9686969;R-HSA-174057;R-HSA-174121;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437
## 29 R-HSA-174144;R-HSA-174119;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174132;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421
## 30 R-HSA-2514854;R-HSA-2529015;R-HSA-2520883;R-HSA-2529020
## 31 R-HSA-163120;R-HSA-606349;R-HSA-174439;R-HSA-9668902;R-HSA-606287;R-HSA-174452;R-HSA-606289;R-HSA-9686521;R-HSA-163096;R-HSA-9668904;R-HSA-174447;R-HSA-606326
## 32 R-HSA-990478;R-HSA-983259;R-HSA-990489;R-HSA-984648;R-HSA-983266;R-HSA-984609
## 33 R-HSA-75809;R-HSA-75010;R-HSA-6799332;R-HSA-170070;R-HSA-170055;R-HSA-8852354;R-HSA-8852337;R-HSA-176298;R-HSA-8852351;R-HSA-75016;R-HSA-9029987;R-HSA-176318
## 34 R-HSA-179410;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174255;R-HSA-179421
## 35 R-HSA-170070;R-HSA-170055
## 36 R-HSA-174144;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421
## 37 R-HSA-174122;R-HSA-174174
## 38 R-HSA-174209;R-HSA-174122;R-HSA-174251;R-HSA-141423;R-HSA-174159;R-HSA-188371;R-HSA-141429;R-HSA-174139;R-HSA-174203;R-HSA-174235;R-HSA-174174;R-HSA-174079;R-HSA-141437
## 39 R-HSA-2984220;R-HSA-2984226
## 40 R-HSA-179410;R-HSA-179417;R-HSA-179421
## 41 R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326
## 42 R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326
## 43 R-HSA-6811426;R-HSA-6811423
## 44 R-HSA-156723;R-HSA-156673
## 45 R-HSA-174171;R-HSA-174104;R-HSA-174255
## 46 R-HSA-2172194;R-HSA-2314566;R-HSA-2172183;R-HSA-2214351
## 47 R-HSA-187552;R-HSA-187520;R-HSA-2468039;R-HSA-174273;R-HSA-174054;R-HSA-2473152;R-HSA-69005;R-HSA-176942;R-HSA-2468041;R-HSA-187948;R-HSA-187916;R-HSA-187949;R-HSA-68944;R-HSA-187574;R-HSA-187575;R-HSA-174164;R-HSA-69015;R-HSA-2473151;R-HSA-187934;R-HSA-174110;R-HSA-176956
## 48 R-HSA-174119;R-HSA-174132
## 49 R-HSA-141429;R-HSA-141423;R-HSA-141437
## 50 R-HSA-141423;R-HSA-141437
## 51 R-HSA-6803875;R-HSA-6798268;R-HSA-6798282
## 52 R-HSA-3000319;R-HSA-3000335;R-HSA-3002798;R-HSA-4086410;R-HSA-3002811;R-HSA-2562526;R-HSA-2574845;R-HSA-3000327;R-HSA-3000310;R-HSA-3000339;R-HSA-2574840
## 53 R-HSA-69754;R-HSA-69756
## 54 R-HSA-9709268;R-HSA-9763200;R-HSA-9709601;R-HSA-9709571;R-HSA-9701199;R-HSA-9704408;R-HSA-9704330;R-HSA-9629245
## 55 R-HSA-174227;R-HSA-174120;R-HSA-174157
## 56 R-HSA-9709601
## 57 R-HSA-6811426;R-HSA-6811423
## 58 R-HSA-9704408;R-HSA-9704330
## 59 R-HSA-9704330
## 60 R-HSA-9701199
## 61 R-HSA-9704408
## 62 R-HSA-6803875;R-HSA-6802973;R-HSA-6798268;R-HSA-187934;R-HSA-6798282
## 63 R-HSA-5693589
## 64 R-HSA-113638
## 65 R-HSA-8869566;R-HSA-8869549
## 66 R-HSA-174195;R-HSA-9686980;R-HSA-174088;R-HSA-9686969;R-HSA-174105;R-HSA-188191
## 67 R-HSA-5686469;R-HSA-5686483;R-HSA-5693539;R-HSA-5693584;R-HSA-5686410;R-HSA-5686440
## 68 R-HSA-5693589;R-HSA-5686469;R-HSA-5686483;R-HSA-5693539;R-HSA-5693584;R-HSA-5686410;R-HSA-5686440
## 69 R-HSA-68944;R-HSA-69015;R-HSA-69005;R-HSA-176942;R-HSA-176956
## 70 R-HSA-75010;R-HSA-176298;R-HSA-176318
## 71 R-HSA-990478;R-HSA-983259;R-HSA-990489;R-HSA-984648;R-HSA-983266;R-HSA-984609
## 72 R-HSA-8852324;R-HSA-8852306;R-HSA-8852354;R-HSA-8852337;R-HSA-8852351;R-HSA-8852317;R-HSA-8852331;R-HSA-8852362;R-HSA-8852298;R-HSA-8852280
## 73 R-HSA-9709268;R-HSA-9763200;R-HSA-9709601;R-HSA-9709571
## 74 R-HSA-9709268;R-HSA-9763200;R-HSA-9709601;R-HSA-9709571;R-HSA-9701199;R-HSA-9704408;R-HSA-9704330
## 75 R-HSA-2430533;R-HSA-2430535;R-HSA-2168079
## 76 R-HSA-176942;R-HSA-176956
## 77 R-HSA-2468039;R-HSA-2473152;R-HSA-2473151;R-HSA-2468041
## 78 R-HSA-5693620;R-HSA-9763137;R-HSA-5685838;R-HSA-5685341;R-HSA-5685242;R-HSA-9709273;R-HSA-5693561
## 79 R-HSA-6811426;R-HSA-6811423
## 80 R-HSA-75809;R-HSA-170070;R-HSA-75016;R-HSA-9029987
## 81 R-HSA-4641350;R-HSA-5228525;R-HSA-4641342;R-HSA-4655355
## 82 R-HSA-9636008;R-HSA-9635996
## 83 R-HSA-9629245
## 84 R-HSA-68960;R-HSA-68615;R-HSA-68712;R-HSA-9734687;R-HSA-69005;R-HSA-176942;R-HSA-68940;R-HSA-9734713;R-HSA-68944;R-HSA-68688;R-HSA-9749350;R-HSA-68914;R-HSA-9749351;R-HSA-68917;R-HSA-68916;R-HSA-69015;R-HSA-68919;R-HSA-68918;R-HSA-9734670;R-HSA-9749320;R-HSA-176956
## 85 R-HSA-174224;R-HSA-174070
## 86 R-HSA-2984220;R-HSA-5195402;R-HSA-5244669;R-HSA-2990882;R-HSA-2984226
## 87 R-HSA-5671970
## 88 R-HSA-5684887;R-HSA-5693589;R-HSA-5684882;R-HSA-5686483;R-HSA-5685011;R-HSA-5693584;R-HSA-5685341;R-HSA-9709273;R-HSA-5693593;R-HSA-5686469;R-HSA-9763137;R-HSA-5684096;R-HSA-5686657;R-HSA-5685838;R-HSA-5693580;R-HSA-5686410;R-HSA-5684875;R-HSA-5693620;R-HSA-5686642;R-HSA-5684081;R-HSA-5693564;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5685156;R-HSA-5693539;R-HSA-5685985;R-HSA-5685994;R-HSA-5686440
## 89 R-HSA-163120;R-HSA-174439;R-HSA-9668902;R-HSA-174452;R-HSA-163096;R-HSA-9686521;R-HSA-9668904;R-HSA-174447
## 90 R-HSA-113638
## 91 R-HSA-9763200
## 92 R-HSA-9709268
## 93 R-HSA-8964475;R-HSA-8964531
## 94 R-HSA-5684887;R-HSA-5693589;R-HSA-5684882;R-HSA-5686483;R-HSA-5685011;R-HSA-5693584;R-HSA-5685341;R-HSA-9709273;R-HSA-5687640;R-HSA-5693593;R-HSA-5686469;R-HSA-9763137;R-HSA-5684096;R-HSA-5686657;R-HSA-5685838;R-HSA-5693580;R-HSA-5686410;R-HSA-5684875;R-HSA-5693620;R-HSA-5686642;R-HSA-5684081;R-HSA-5693564;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5685156;R-HSA-5693539;R-HSA-5685985;R-HSA-5685994;R-HSA-5686440
## 95 R-HSA-380294;R-HSA-380272;R-HSA-380303
## 96 R-HSA-380272;R-HSA-380303
## 97 R-HSA-5693620;R-HSA-5693589;R-HSA-5686483;R-HSA-5693584;R-HSA-5685341;R-HSA-5685242;R-HSA-9709273;R-HSA-5693593;R-HSA-5693561;R-HSA-5686469;R-HSA-5693539;R-HSA-9763137;R-HSA-5685838;R-HSA-5686410;R-HSA-5686440
## 98 R-HSA-2245218;R-HSA-2430533;R-HSA-2430535;R-HSA-2172194;R-HSA-5195402;R-HSA-2314566;R-HSA-2294600;R-HSA-5244669;R-HSA-2294574;R-HSA-2168079;R-HSA-2214351;R-HSA-2990882;R-HSA-2984226;R-HSA-2984220;R-HSA-380278;R-HSA-2172183;R-HSA-2294580;R-HSA-2294590
## 99 R-HSA-9624800
## 100 R-HSA-8853405;R-HSA-8853419
## 101 R-HSA-2213248
## 102 R-HSA-75809;R-HSA-6799332;R-HSA-170070;R-HSA-75016;R-HSA-9029987
## 103 R-HSA-380311;R-HSA-380455;R-HSA-380283
## 104 R-HSA-380311;R-HSA-380455;R-HSA-380294;R-HSA-380272;R-HSA-380303;R-HSA-380283
## 105 R-HSA-163120;R-HSA-163096;R-HSA-9686521
## 106 R-HSA-9709571
## 107 R-HSA-68960;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-68940
## 108 R-HSA-163010
## 109 R-HSA-68944;R-HSA-69015;R-HSA-69005
## 110 R-HSA-176942;R-HSA-176956
## 111 R-HSA-6805126;R-HSA-6805109;R-HSA-6799332;R-HSA-6805122
## 112 R-HSA-380316;R-HSA-380508
## 113 R-HSA-5684887;R-HSA-5693589;R-HSA-5684882;R-HSA-5686483;R-HSA-5685011;R-HSA-5693584;R-HSA-5685341;R-HSA-9709273;R-HSA-5687640;R-HSA-5693593;R-HSA-5686469;R-HSA-9763137;R-HSA-5684096;R-HSA-5686657;R-HSA-5685838;R-HSA-5693580;R-HSA-5686410;R-HSA-5684875;R-HSA-5693620;R-HSA-5686642;R-HSA-5684081;R-HSA-5693564;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5685156;R-HSA-5693539;R-HSA-5685985;R-HSA-5685994;R-HSA-5686440
## 114 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 115 R-HSA-9763137;R-HSA-5685341;R-HSA-5685242;R-HSA-9709273;R-HSA-5693561
## 116 R-HSA-2990882
## 117 R-HSA-9696271
## 118 R-HSA-6793661
## 119 R-HSA-6805126;R-HSA-6805109;R-HSA-6799332;R-HSA-6805122;R-HSA-6793661
## 120 R-HSA-9696266
## 121 R-HSA-163120;R-HSA-174439;R-HSA-9668902;R-HSA-174452;R-HSA-163096;R-HSA-9686521;R-HSA-9668904;R-HSA-174447
## 122 R-HSA-8961982;R-HSA-9007591
## 123 R-HSA-6793661
## 124 R-HSA-187937;R-HSA-187959
## 125 R-HSA-8869566;R-HSA-8869549
## 126 R-HSA-68688
## 127 R-HSA-9629245
## 128 R-HSA-2245218;R-HSA-2294580;R-HSA-2294600;R-HSA-2294574;R-HSA-2294590
## 129 R-HSA-140355;R-HSA-140359
## 130 R-HSA-912429;R-HSA-912458;R-HSA-912503;R-HSA-912496
## 131 R-HSA-1296037
## 132 R-HSA-68960;R-HSA-68615;R-HSA-68712;R-HSA-9734687;R-HSA-68940;R-HSA-9734713;R-HSA-68688;R-HSA-9749350;R-HSA-68914;R-HSA-9749351;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-9734670;R-HSA-9749320
## 133 R-HSA-174144;R-HSA-174202;R-HSA-174121
## 134 R-HSA-112342
## 135 R-HSA-68944
## 136 R-HSA-69015;R-HSA-69005
## 137 R-HSA-5687640
## 138 R-HSA-418549
## 139 R-HSA-9624800
## 140 R-HSA-9687377
## 141 R-HSA-187934
## 142 R-HSA-5693542;R-HSA-5684887;R-HSA-5685156;R-HSA-5684882;R-HSA-5685011;R-HSA-5684096;R-HSA-5684081;R-HSA-5685985;R-HSA-5685994;R-HSA-5684875
## 143 R-HSA-3790137;R-HSA-3788705;R-HSA-3790130;R-HSA-3788725;R-HSA-3788708;R-HSA-3788724
## 144 R-HSA-6805126;R-HSA-6805109;R-HSA-6799332;R-HSA-6803875;R-HSA-6805122;R-HSA-6793661;R-HSA-6802973;R-HSA-6798268;R-HSA-187934;R-HSA-6798282
## 145 R-HSA-912429;R-HSA-912458;R-HSA-912503;R-HSA-912496
## 146 R-HSA-5358545;R-HSA-5684887;R-HSA-5693589;R-HSA-5684882;R-HSA-5686483;R-HSA-5685011;R-HSA-5693584;R-HSA-5358619;R-HSA-5685341;R-HSA-9629470;R-HSA-9709273;R-HSA-5687640;R-HSA-9635996;R-HSA-5693593;R-HSA-5686469;R-HSA-5358597;R-HSA-9763137;R-HSA-5684096;R-HSA-5358599;R-HSA-5686657;R-HSA-5685838;R-HSA-9629195;R-HSA-5693580;R-HSA-5686410;R-HSA-5684875;R-HSA-5693620;R-HSA-5686642;R-HSA-9629492;R-HSA-5684081;R-HSA-9629365;R-HSA-9629499;R-HSA-5693564;R-HSA-9629497;R-HSA-9629369;R-HSA-5685242;R-HSA-9629372;R-HSA-5693561;R-HSA-9629373;R-HSA-5693542;R-HSA-9629216;R-HSA-5685156;R-HSA-5693539;R-HSA-5685985;R-HSA-9629483;R-HSA-9636008;R-HSA-5685994;R-HSA-9629358;R-HSA-5686440
## 147 R-HSA-5358545;R-HSA-5358619
## 148 R-HSA-5358597;R-HSA-5358599
## 149 R-HSA-400496
## 150 R-HSA-4641350;R-HSA-5228525;R-HSA-4641342;R-HSA-4655355
## 151 R-HSA-5195402;R-HSA-5244669
## 152 R-HSA-5358545;R-HSA-5358597;R-HSA-5358599;R-HSA-5358619
## 153 R-HSA-4641350;R-HSA-5228525;R-HSA-4641342;R-HSA-4655355
## 154 R-HSA-422051
## 155 R-HSA-112342
## 156 R-HSA-6802973
## 157 R-HSA-9017855
## 158 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 159 R-HSA-8863011;R-HSA-8863674
## 160 R-HSA-8863011;R-HSA-8863674
## 161 R-HSA-68688;R-HSA-9749350;R-HSA-9749351;R-HSA-68615;R-HSA-68712;R-HSA-9734670;R-HSA-9734687;R-HSA-9749320;R-HSA-9734713
## 162 R-HSA-174439;R-HSA-9668902;R-HSA-174452;R-HSA-9668904;R-HSA-174447
## 163 R-HSA-8852130;R-HSA-8852129
## 164 R-HSA-8863011;R-HSA-8863674
## 165 R-HSA-73632
## 166 R-HSA-418549
## 167 R-HSA-9687377
## 168 R-HSA-9629365;R-HSA-9629195;R-HSA-9629358;R-HSA-9629373
## 169 R-HSA-9687377
## 170 R-HSA-5686642;R-HSA-5686657;R-HSA-5693564;R-HSA-5693580
## 171 R-HSA-9018794
## 172 R-HSA-68615;R-HSA-9734670;R-HSA-9734687;R-HSA-9734713
## 173 R-HSA-9023132
## 174 R-HSA-9629369;R-HSA-9629372
## 175 R-HSA-6814387;R-HSA-6814764;R-HSA-6814298
## 176 R-HSA-9696268
## 177 R-HSA-9629216;R-HSA-9629492;R-HSA-9629483;R-HSA-9629470
## 178 R-HSA-9018766
## 179 R-HSA-8940100
## 180 R-HSA-9629216;R-HSA-9629492;R-HSA-9629365;R-HSA-9629483;R-HSA-9629195;R-HSA-9629470;R-HSA-9629358;R-HSA-9629373
## 181 R-HSA-912429;R-HSA-912458;R-HSA-912503;R-HSA-912496
## 182 R-HSA-9693282
## 183 R-HSA-400459
## 184 R-HSA-3790130
## 185 R-HSA-174439;R-HSA-9668902;R-HSA-174452;R-HSA-9668904;R-HSA-174447
## 186 R-HSA-9629499;R-HSA-9629497
## 187 R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-9629372
## 188 R-HSA-400496;R-HSA-400459
## 189 R-HSA-174209;R-HSA-174203;R-HSA-174159
## 190 R-HSA-9604675
## 191 R-HSA-9013437
## 192 R-HSA-140355;R-HSA-2314678;R-HSA-140359;R-HSA-9677320
## 193 R-HSA-5692755;R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-9604675;R-HSA-5671749;R-HSA-112342;R-HSA-9013022;R-HSA-9013009;R-HSA-419166;R-HSA-9017488;R-HSA-9696266;R-HSA-9696271;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-5666160;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-205039;R-HSA-5666169;R-HSA-5671737;R-HSA-9018745;R-HSA-9018808;R-HSA-9693282;R-HSA-9018746;R-HSA-9013437;R-HSA-5671970;R-HSA-9017855;R-HSA-9014449;R-HSA-9013111;R-HSA-9018806;R-HSA-9013110
## 194 R-HSA-5697009;R-HSA-5696958;R-HSA-8940100
## 195 R-HSA-9017488;R-HSA-9017507
## 196 R-HSA-6811426;R-HSA-6811423
## 197 R-HSA-6805126;R-HSA-6799332;R-HSA-6803875;R-HSA-6805122;R-HSA-376419;R-HSA-8869549;R-HSA-9009282;R-HSA-3790130;R-HSA-6798282;R-HSA-975040;R-HSA-9007591;R-HSA-6805109;R-HSA-9023132;R-HSA-382096;R-HSA-8961982;R-HSA-8869566;R-HSA-6793661;R-HSA-6802973;R-HSA-6798268;R-HSA-187934
## 198 R-HSA-990478;R-HSA-418549;R-HSA-983259;R-HSA-990489;R-HSA-984648;R-HSA-983266;R-HSA-984609
## 199 R-HSA-187552;R-HSA-187520;R-HSA-187574;R-HSA-187575
## 200 R-HSA-9629492;R-HSA-9629365;R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-9629470;R-HSA-9629372;R-HSA-9635996;R-HSA-9629373;R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9636008;R-HSA-9629358
## 201 R-HSA-9018745;R-HSA-9018746
## 202 R-HSA-9017855
## 203 R-HSA-174058;R-HSA-174057
## 204 R-HSA-205039
## 205 R-HSA-73632
## 206 R-HSA-187934
## 207 R-HSA-187934
## 208 R-HSA-187934
## 209 R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 210 R-HSA-9013145;R-HSA-9013144;R-HSA-9013143
## 211 R-HSA-187934
## 212 R-HSA-9013022;R-HSA-9013024
## 213 R-HSA-3790137;R-HSA-3788705;R-HSA-3790130;R-HSA-187934;R-HSA-3788725;R-HSA-3788708;R-HSA-3788724
## 214 R-HSA-9014449;R-HSA-9014434
## 215 R-HSA-9013111;R-HSA-9013110
## 216 R-HSA-5671749;R-HSA-75016;R-HSA-5671737
## 217 R-HSA-2855252
## 218 R-HSA-5697009;R-HSA-5696958
## 219 R-HSA-111751;R-HSA-111742
## 220 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 221 R-HSA-205039
## 222 R-HSA-8852130;R-HSA-8852129
## 223 R-HSA-382096;R-HSA-376419
## 224 R-HSA-419166
## 225 R-HSA-187552;R-HSA-187520;R-HSA-187574;R-HSA-187575
## 226 R-HSA-9836184
## 227 R-HSA-2855252
## 228 R-HSA-187552;R-HSA-187520;R-HSA-174273;R-HSA-174054;R-HSA-187574;R-HSA-187575;R-HSA-174164;R-HSA-187934;R-HSA-174110;R-HSA-187948;R-HSA-187916;R-HSA-187949
## 229 R-HSA-6805126;R-HSA-6799332;R-HSA-6803875;R-HSA-6805122;R-HSA-376419;R-HSA-8869549;R-HSA-9009282;R-HSA-3790130;R-HSA-6798282;R-HSA-975040;R-HSA-9007591;R-HSA-6805109;R-HSA-9023132;R-HSA-382096;R-HSA-8961982;R-HSA-8869566;R-HSA-6793661;R-HSA-6802973;R-HSA-6798268;R-HSA-187934
## 230 R-HSA-9014295;R-HSA-9014294
## 231 R-HSA-9604675
## 232 R-HSA-6814387;R-HSA-6814764;R-HSA-6814298
## 233 R-HSA-8863011;R-HSA-8863674
## 234 R-HSA-9629492;R-HSA-9629365;R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-9629470;R-HSA-9629372;R-HSA-9635996;R-HSA-9629373;R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9636008;R-HSA-9629358
## 235 R-HSA-2213248;R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 236 R-HSA-9018808;R-HSA-9018806
## 237 R-HSA-9023132
## 238 R-HSA-5692755
## 239 R-HSA-1296037
## 240 R-HSA-205039
## 241 R-HSA-73632;R-HSA-111751;R-HSA-111742
## 242 R-HSA-6811426;R-HSA-6811423
## 243 R-HSA-8940388
## 244 R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 245 R-HSA-418549
## 246 R-HSA-1799329
## 247 R-HSA-422051;R-HSA-400496;R-HSA-400459
## 248 R-HSA-6805126;R-HSA-6799332;R-HSA-6803875;R-HSA-6805122;R-HSA-376419;R-HSA-8869549;R-HSA-9009282;R-HSA-3790130;R-HSA-6798282;R-HSA-975040;R-HSA-9007591;R-HSA-6805109;R-HSA-9023132;R-HSA-382096;R-HSA-8961982;R-HSA-8869566;R-HSA-6793661;R-HSA-6802973;R-HSA-6798268;R-HSA-187934
## 249 R-HSA-9018766;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-9013022;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-9696271;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-9018745;R-HSA-9018808;R-HSA-9693282;R-HSA-9018746;R-HSA-9013437;R-HSA-9014449;R-HSA-9013111;R-HSA-9018806;R-HSA-9013110
## 250 R-HSA-9009282
## 251 R-HSA-9013009;R-HSA-8981637
## 252 R-HSA-9013161;R-HSA-9013157
## 253 R-HSA-140355;R-HSA-2314678;R-HSA-140359;R-HSA-9677320
## 254 R-HSA-2855252
## 255 R-HSA-205039
## 256 R-HSA-9836184
## 257 R-HSA-9604675;R-HSA-9017855
## 258 R-HSA-140355;R-HSA-140359
## 259 R-HSA-112342
## 260 R-HSA-4641350;R-HSA-5228525;R-HSA-8852130;R-HSA-8852129;R-HSA-5697009;R-HSA-4641342;R-HSA-5696958;R-HSA-8940100;R-HSA-4655355;R-HSA-8940388
## 261 R-HSA-1799329
## 262 R-HSA-5692755;R-HSA-112342
## 263 R-HSA-2855252
## 264 R-HSA-9836184
## 265 R-HSA-140355;R-HSA-2314678;R-HSA-140359;R-HSA-9677320
## 266 R-HSA-1296037
## 267 R-HSA-140355;R-HSA-140359
## 268 R-HSA-4641350;R-HSA-5228525;R-HSA-422051;R-HSA-8852130;R-HSA-8852129;R-HSA-5697009;R-HSA-5696958;R-HSA-8940100;R-HSA-8940388;R-HSA-400459;R-HSA-400496;R-HSA-4641342;R-HSA-1799329;R-HSA-4655355
## 269 R-HSA-3790137;R-HSA-3788705;R-HSA-3790130;R-HSA-187934;R-HSA-3788725;R-HSA-3788708;R-HSA-3788724
## 270 R-HSA-3790137;R-HSA-3788705;R-HSA-3790130;R-HSA-187934;R-HSA-3788725;R-HSA-3788708;R-HSA-3788724
## 271 R-HSA-419166
## 272 R-HSA-419166
## 273 R-HSA-2213248;R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-9836184;R-HSA-983152
## 274 R-HSA-9836184
## 275 R-HSA-6814387;R-HSA-6814764;R-HSA-6814298
## 276 R-HSA-9709268;R-HSA-9687377;R-HSA-8863011;R-HSA-9763200;R-HSA-9709601;R-HSA-9709571;R-HSA-9701199;R-HSA-9704408;R-HSA-8863674;R-HSA-9704330;R-HSA-9629245
## 277 R-HSA-2855252
## 278 R-HSA-140355;R-HSA-2314678;R-HSA-140359;R-HSA-9677320
## 279 R-HSA-73632;R-HSA-140355;R-HSA-2314678;R-HSA-140359;R-HSA-111751;R-HSA-9677320;R-HSA-2855252;R-HSA-111742
For the top 100 downregulated genes:
result_down <- read.csv("result_down.csv")
result_down## Pathway.identifier
## 1 R-HSA-141424
## 2 R-HSA-141444
## 3 R-HSA-69618
## 4 R-HSA-156711
## 5 R-HSA-2500257
## 6 R-HSA-68877
## 7 R-HSA-2467813
## 8 R-HSA-69278
## 9 R-HSA-68886
## 10 R-HSA-1640170
## 11 R-HSA-69620
## 12 R-HSA-9648025
## 13 R-HSA-2555396
## 14 R-HSA-68882
## 15 R-HSA-195258
## 16 R-HSA-194315
## 17 R-HSA-5663220
## 18 R-HSA-9716542
## 19 R-HSA-69275
## 20 R-HSA-453274
## 21 R-HSA-453276
## 22 R-HSA-174143
## 23 R-HSA-2559586
## 24 R-HSA-176814
## 25 R-HSA-983189
## 26 R-HSA-69273
## 27 R-HSA-176409
## 28 R-HSA-69481
## 29 R-HSA-2559583
## 30 R-HSA-179409
## 31 R-HSA-140342
## 32 R-HSA-6811434
## 33 R-HSA-2559584
## 34 R-HSA-69478
## 35 R-HSA-176408
## 36 R-HSA-141405
## 37 R-HSA-141430
## 38 R-HSA-69306
## 39 R-HSA-453279
## 40 R-HSA-179419
## 41 R-HSA-8856688
## 42 R-HSA-983231
## 43 R-HSA-2299718
## 44 R-HSA-75153
## 45 R-HSA-2514853
## 46 R-HSA-68875
## 47 R-HSA-2132295
## 48 R-HSA-6791312
## 49 R-HSA-1538133
## 50 R-HSA-176412
## 51 R-HSA-6804114
## 52 R-HSA-174184
## 53 R-HSA-174178
## 54 R-HSA-8854518
## 55 R-HSA-176417
## 56 R-HSA-174048
## 57 R-HSA-69473
## 58 R-HSA-2980767
## 59 R-HSA-6811442
## 60 R-HSA-2995383
## 61 R-HSA-606279
## 62 R-HSA-774815
## 63 R-HSA-2559582
## 64 R-HSA-69002
## 65 R-HSA-2565942
## 66 R-HSA-73886
## 67 R-HSA-9687139
## 68 R-HSA-75035
## 69 R-HSA-68884
## 70 R-HSA-9675126
## 71 R-HSA-68867
## 72 R-HSA-162582
## 73 R-HSA-162658
## 74 R-HSA-212300
## 75 R-HSA-69242
## 76 R-HSA-69239
## 77 R-HSA-4615885
## 78 R-HSA-176407
## 79 R-HSA-69052
## 80 R-HSA-9645723
## 81 R-HSA-9013405
## 82 R-HSA-69206
## 83 R-HSA-9018519
## 84 R-HSA-8980692
## 85 R-HSA-1221632
## 86 R-HSA-157579
## 87 R-HSA-9821993
## 88 R-HSA-2980766
## 89 R-HSA-174154
## 90 R-HSA-171306
## 91 R-HSA-73728
## 92 R-HSA-5334118
## 93 R-HSA-9013026
## 94 R-HSA-69017
## 95 R-HSA-110330
## 96 R-HSA-5625740
## 97 R-HSA-9013106
## 98 R-HSA-176187
## 99 R-HSA-68616
## 100 R-HSA-176974
## 101 R-HSA-110328
## 102 R-HSA-109581
## 103 R-HSA-8852276
## 104 R-HSA-8852135
## 105 R-HSA-427359
## 106 R-HSA-110331
## 107 R-HSA-2995410
## 108 R-HSA-5693607
## 109 R-HSA-73927
## 110 R-HSA-1500620
## 111 R-HSA-9670095
## 112 R-HSA-427389
## 113 R-HSA-5625886
## 114 R-HSA-9821002
## 115 R-HSA-5661231
## 116 R-HSA-110329
## 117 R-HSA-73928
## 118 R-HSA-9710421
## 119 R-HSA-9661069
## 120 R-HSA-9659787
## 121 R-HSA-9013423
## 122 R-HSA-5693571
## 123 R-HSA-9012999
## 124 R-HSA-912446
## 125 R-HSA-9687136
## 126 R-HSA-1362300
## 127 R-HSA-6804116
## 128 R-HSA-5357801
## 129 R-HSA-73772
## 130 R-HSA-5660526
## 131 R-HSA-5250924
## 132 R-HSA-73929
## 133 R-HSA-5617472
## 134 R-HSA-5619507
## 135 R-HSA-3214815
## 136 R-HSA-9012852
## 137 R-HSA-3700989
## 138 R-HSA-4419969
## 139 R-HSA-5625900
## 140 R-HSA-3108232
## 141 R-HSA-201722
## 142 R-HSA-8939211
## 143 R-HSA-5693565
## 144 R-HSA-157118
## 145 R-HSA-1362277
## 146 R-HSA-5693567
## 147 R-HSA-8953897
## 148 R-HSA-9616222
## 149 R-HSA-2990846
## 150 R-HSA-380284
## 151 R-HSA-380259
## 152 R-HSA-5693538
## 153 R-HSA-6803205
## 154 R-HSA-5693606
## 155 R-HSA-8936459
## 156 R-HSA-9816359
## 157 R-HSA-352238
## 158 R-HSA-8862803
## 159 R-HSA-8863678
## 160 R-HSA-427413
## 161 R-HSA-5250913
## 162 R-HSA-5578749
## 163 R-HSA-380270
## 164 R-HSA-1474165
## 165 R-HSA-380287
## 166 R-HSA-8866652
## 167 R-HSA-9734009
## 168 R-HSA-73854
## 169 R-HSA-171319
## 170 R-HSA-73864
## 171 R-HSA-8854521
## 172 R-HSA-68881
## 173 R-HSA-1280218
## 174 R-HSA-69202
## 175 R-HSA-5250941
## 176 R-HSA-1912408
## 177 R-HSA-68962
## 178 R-HSA-9013508
## 179 R-HSA-977225
## 180 R-HSA-69656
## 181 R-HSA-9013404
## 182 R-HSA-69190
## 183 R-HSA-9013148
## 184 R-HSA-170145
## 185 R-HSA-6804756
## 186 R-HSA-380320
## 187 R-HSA-5620912
## 188 R-HSA-73884
## 189 R-HSA-3301854
## 190 R-HSA-5693532
## 191 R-HSA-9696273
## 192 R-HSA-69200
## 193 R-HSA-9007892
## 194 R-HSA-9696270
## 195 R-HSA-8939236
## 196 R-HSA-109582
## 197 R-HSA-9035034
## 198 R-HSA-212165
## 199 R-HSA-9014826
## 200 R-HSA-68911
## 201 R-HSA-8853884
## 202 R-HSA-3214847
## 203 R-HSA-2559580
## 204 R-HSA-1912422
## 205 R-HSA-2262752
## 206 R-HSA-69236
## 207 R-HSA-69231
## 208 R-HSA-9013149
## 209 R-HSA-211000
## 210 R-HSA-113507
## 211 R-HSA-449147
## 212 R-HSA-199991
## 213 R-HSA-5689880
## 214 R-HSA-8866654
## 215 R-HSA-9006931
## 216 R-HSA-6785807
## 217 R-HSA-187577
## 218 R-HSA-2465910
## 219 R-HSA-174084
## 220 R-HSA-180786
## 221 R-HSA-190377
## 222 R-HSA-69580
## 223 R-HSA-69563
## 224 R-HSA-69615
## 225 R-HSA-68949
## 226 R-HSA-8950505
## 227 R-HSA-191273
## 228 R-HSA-9013408
## 229 R-HSA-2160916
## 230 R-HSA-5578768
## 231 R-HSA-5633008
## 232 R-HSA-9020591
## 233 R-HSA-6783783
## 234 R-HSA-5633007
## 235 R-HSA-2142845
## 236 R-HSA-113510
## 237 R-HSA-447115
## 238 R-HSA-212436
## 239 R-HSA-190241
## 240 R-HSA-2022377
## 241 R-HSA-5688426
## 242 R-HSA-6804115
## 243 R-HSA-9013507
## 244 R-HSA-5653656
## 245 R-HSA-3214842
## 246 R-HSA-5617833
## 247 R-HSA-983168
## 248 R-HSA-9609690
## 249 R-HSA-201681
## 250 R-HSA-1280215
## 251 R-HSA-111465
## 252 R-HSA-195721
## 253 R-HSA-9013424
## 254 R-HSA-9022692
## 255 R-HSA-390471
## 256 R-HSA-73857
## 257 R-HSA-9696264
## 258 R-HSA-6804757
## 259 R-HSA-9013420
## 260 R-HSA-6806003
## 261 R-HSA-9820841
## 262 R-HSA-3214841
## 263 R-HSA-4839726
## 264 R-HSA-3247509
## 265 R-HSA-74160
## 266 R-HSA-8878171
## 267 R-HSA-168256
## 268 R-HSA-3214858
## 269 R-HSA-73894
## 270 R-HSA-174113
## 271 R-HSA-8854050
## 272 R-HSA-437239
## 273 R-HSA-9609646
## 274 R-HSA-9604323
## 275 R-HSA-9013409
## 276 R-HSA-4551638
## 277 R-HSA-9013406
## 278 R-HSA-193648
## 279 R-HSA-9610379
## 280 R-HSA-983169
## 281 R-HSA-877300
## 282 R-HSA-446652
## 283 R-HSA-2426168
## 284 R-HSA-9749641
## 285 R-HSA-204998
## 286 R-HSA-375276
## 287 R-HSA-383280
## 288 R-HSA-216083
## 289 R-HSA-416482
## 290 R-HSA-1852241
## 291 R-HSA-1655829
## 292 R-HSA-5654738
## 293 R-HSA-9013694
## 294 R-HSA-390466
## 295 R-HSA-156902
## 296 R-HSA-4086400
## 297 R-HSA-8986944
## 298 R-HSA-975956
## 299 R-HSA-156842
## 300 R-HSA-391251
## 301 R-HSA-72764
## 302 R-HSA-72689
## 303 R-HSA-5687128
## 304 R-HSA-381340
## 305 R-HSA-190236
## 306 R-HSA-193704
## 307 R-HSA-2408557
## 308 R-HSA-192823
## 309 R-HSA-8951664
## 310 R-HSA-9633012
## 311 R-HSA-1799339
## 312 R-HSA-72706
## 313 R-HSA-156827
## 314 R-HSA-927802
## 315 R-HSA-975957
## 316 R-HSA-9020702
## 317 R-HSA-597592
## 318 R-HSA-72613
## 319 R-HSA-72737
## 320 R-HSA-373760
## 321 R-HSA-2980736
## 322 R-HSA-5576891
## 323 R-HSA-8878166
## 324 R-HSA-166016
## 325 R-HSA-3858494
## 326 R-HSA-9679191
## 327 R-HSA-8957322
## 328 R-HSA-73887
## 329 R-HSA-168273
## 330 R-HSA-1989781
## 331 R-HSA-9711097
## 332 R-HSA-400206
## 333 R-HSA-2408522
## 334 R-HSA-9010553
## 335 R-HSA-1630316
## 336 R-HSA-6791226
## 337 R-HSA-392499
## 338 R-HSA-168255
## 339 R-HSA-168898
## 340 R-HSA-8868773
## 341 R-HSA-913531
## 342 R-HSA-373076
## 343 R-HSA-397014
## 344 R-HSA-376176
## 345 R-HSA-9748784
## 346 R-HSA-72312
## 347 R-HSA-198933
## 348 R-HSA-202733
## 349 R-HSA-416476
## 350 R-HSA-211945
## 351 R-HSA-1474244
## 352 R-HSA-9824446
## 353 R-HSA-72766
## 354 R-HSA-422475
## 355 R-HSA-1266738
## 356 R-HSA-5683057
## 357 R-HSA-500792
## 358 R-HSA-9675108
## 359 R-HSA-418594
## 360 R-HSA-372790
## 361 R-HSA-71387
## 362 R-HSA-6798695
## 363 R-HSA-211859
## 364 R-HSA-388396
## 365 R-HSA-9679506
## 366 R-HSA-5663205
## 367 R-HSA-1643685
## 368 R-HSA-9006934
## 369 R-HSA-71291
## 370 R-HSA-8953854
## 371 R-HSA-556833
## 372 R-HSA-168249
## 373 R-HSA-1430728
## Pathway.name
## 1 Amplification of signal from the kinetochores
## 2 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
## 3 Mitotic Spindle Checkpoint
## 4 Polo-like kinase mediated events
## 5 Resolution of Sister Chromatid Cohesion
## 6 Mitotic Prometaphase
## 7 Separation of Sister Chromatids
## 8 Cell Cycle, Mitotic
## 9 M Phase
## 10 Cell Cycle
## 11 Cell Cycle Checkpoints
## 12 EML4 and NUDC in mitotic spindle formation
## 13 Mitotic Metaphase and Anaphase
## 14 Mitotic Anaphase
## 15 RHO GTPase Effectors
## 16 Signaling by Rho GTPases
## 17 RHO GTPases Activate Formins
## 18 Signaling by Rho GTPases, Miro GTPases and RHOBTB3
## 19 G2/M Transition
## 20 Mitotic G2-G2/M phases
## 21 Regulation of mitotic cell cycle
## 22 APC/C-mediated degradation of cell cycle proteins
## 23 DNA Damage/Telomere Stress Induced Senescence
## 24 Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
## 25 Kinesins
## 26 Cyclin A/B1/B2 associated events during G2/M transition
## 27 APC/C:Cdc20 mediated degradation of mitotic proteins
## 28 G2/M Checkpoints
## 29 Cellular Senescence
## 30 APC-Cdc20 mediated degradation of Nek2A
## 31 Apoptosis induced DNA fragmentation
## 32 COPI-dependent Golgi-to-ER retrograde traffic
## 33 Formation of Senescence-Associated Heterochromatin Foci (SAHF)
## 34 G2/M DNA replication checkpoint
## 35 Regulation of APC/C activators between G1/S and early anaphase
## 36 Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
## 37 Inactivation of APC/C via direct inhibition of the APC/C complex
## 38 DNA Replication
## 39 Mitotic G1 phase and G1/S transition
## 40 APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
## 41 Golgi-to-ER retrograde transport
## 42 Factors involved in megakaryocyte development and platelet production
## 43 Condensation of Prophase Chromosomes
## 44 Apoptotic execution phase
## 45 Condensation of Prometaphase Chromosomes
## 46 Mitotic Prophase
## 47 MHC class II antigen presentation
## 48 TP53 Regulates Transcription of Cell Cycle Genes
## 49 G0 and Early G1
## 50 Phosphorylation of the APC/C
## 51 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
## 52 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
## 53 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
## 54 AURKA Activation by TPX2
## 55 Phosphorylation of Emi1
## 56 APC/C:Cdc20 mediated degradation of Cyclin B
## 57 G2/M DNA damage checkpoint
## 58 Activation of NIMA Kinases NEK9, NEK6, NEK7
## 59 Intra-Golgi and retrograde Golgi-to-ER traffic
## 60 Initiation of Nuclear Envelope (NE) Reformation
## 61 Deposition of new CENPA-containing nucleosomes at the centromere
## 62 Nucleosome assembly
## 63 Senescence-Associated Secretory Phenotype (SASP)
## 64 DNA Replication Pre-Initiation
## 65 Regulation of PLK1 Activity at G2/M Transition
## 66 Chromosome Maintenance
## 67 Aberrant regulation of mitotic cell cycle due to RB1 defects
## 68 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
## 69 Mitotic Telophase/Cytokinesis
## 70 Diseases of mitotic cell cycle
## 71 Assembly of the pre-replicative complex
## 72 Signal Transduction
## 73 Golgi Cisternae Pericentriolar Stack Reorganization
## 74 PRC2 methylates histones and DNA
## 75 S Phase
## 76 Synthesis of DNA
## 77 SUMOylation of DNA replication proteins
## 78 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
## 79 Switching of origins to a post-replicative state
## 80 Diseases of programmed cell death
## 81 RHOD GTPase cycle
## 82 G1/S Transition
## 83 Estrogen-dependent gene expression
## 84 RHOA GTPase cycle
## 85 Meiotic synapsis
## 86 Telomere Maintenance
## 87 Replacement of protamines by nucleosomes in the male pronucleus
## 88 Nuclear Envelope Breakdown
## 89 APC/C:Cdc20 mediated degradation of Securin
## 90 Packaging Of Telomere Ends
## 91 RNA Polymerase I Promoter Opening
## 92 DNA methylation
## 93 RHOB GTPase cycle
## 94 CDK-mediated phosphorylation and removal of Cdc6
## 95 Recognition and association of DNA glycosylase with site containing an affected purine
## 96 RHO GTPases activate PKNs
## 97 RHOC GTPase cycle
## 98 Activation of ATR in response to replication stress
## 99 Assembly of the ORC complex at the origin of replication
## 100 Unwinding of DNA
## 101 Recognition and association of DNA glycosylase with site containing an affected pyrimidine
## 102 Apoptosis
## 103 The role of GTSE1 in G2/M progression after G2 checkpoint
## 104 Protein ubiquitination
## 105 SIRT1 negatively regulates rRNA expression
## 106 Cleavage of the damaged purine
## 107 Nuclear Envelope (NE) Reassembly
## 108 Processing of DNA double-strand break ends
## 109 Depurination
## 110 Meiosis
## 111 Inhibition of DNA recombination at telomere
## 112 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
## 113 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
## 114 Chromatin modifications during the maternal to zygotic transition (MZT)
## 115 Metallothioneins bind metals
## 116 Cleavage of the damaged pyrimidine
## 117 Depyrimidination
## 118 Defective pyroptosis
## 119 Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
## 120 Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects
## 121 RAC3 GTPase cycle
## 122 Nonhomologous End-Joining (NHEJ)
## 123 RHO GTPase cycle
## 124 Meiotic recombination
## 125 Aberrant regulation of mitotic exit in cancer due to RB1 defects
## 126 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
## 127 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
## 128 Programmed Cell Death
## 129 RNA Polymerase I Promoter Escape
## 130 Response to metal ions
## 131 B-WICH complex positively regulates rRNA expression
## 132 Base-Excision Repair, AP Site Formation
## 133 Activation of anterior HOX genes in hindbrain development during early embryogenesis
## 134 Activation of HOX genes during differentiation
## 135 HDACs deacetylate histones
## 136 Signaling by NOTCH3
## 137 Transcriptional Regulation by TP53
## 138 Depolymerization of the Nuclear Lamina
## 139 RHO GTPases activate CIT
## 140 SUMO E3 ligases SUMOylate target proteins
## 141 Formation of the beta-catenin:TCF transactivating complex
## 142 ESR-mediated signaling
## 143 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
## 144 Signaling by NOTCH
## 145 Transcription of E2F targets under negative control by DREAM complex
## 146 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
## 147 Cellular responses to stimuli
## 148 Transcriptional regulation of granulopoiesis
## 149 SUMOylation
## 150 Loss of proteins required for interphase microtubule organization from the centrosome
## 151 Loss of Nlp from mitotic centrosomes
## 152 Homology Directed Repair
## 153 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
## 154 DNA Double Strand Break Response
## 155 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
## 156 Maternal to zygotic transition (MZT)
## 157 Breakdown of the nuclear lamina
## 158 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
## 159 Neurodegenerative Diseases
## 160 NoRC negatively regulates rRNA expression
## 161 Positive epigenetic regulation of rRNA expression
## 162 Transcriptional regulation by small RNAs
## 163 Recruitment of mitotic centrosome proteins and complexes
## 164 Reproduction
## 165 Centrosome maturation
## 166 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
## 167 Defective Intrinsic Pathway for Apoptosis
## 168 RNA Polymerase I Promoter Clearance
## 169 Telomere Extension By Telomerase
## 170 RNA Polymerase I Transcription
## 171 Interaction between PHLDA1 and AURKA
## 172 Mitotic Metaphase/Anaphase Transition
## 173 Adaptive Immune System
## 174 Cyclin E associated events during G1/S transition
## 175 Negative epigenetic regulation of rRNA expression
## 176 Pre-NOTCH Transcription and Translation
## 177 Activation of the pre-replicative complex
## 178 NOTCH3 Intracellular Domain Regulates Transcription
## 179 Amyloid fiber formation
## 180 Cyclin A:Cdk2-associated events at S phase entry
## 181 RAC2 GTPase cycle
## 182 DNA strand elongation
## 183 CDC42 GTPase cycle
## 184 Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
## 185 Regulation of TP53 Activity through Phosphorylation
## 186 Recruitment of NuMA to mitotic centrosomes
## 187 Anchoring of the basal body to the plasma membrane
## 188 Base Excision Repair
## 189 Nuclear Pore Complex (NPC) Disassembly
## 190 DNA Double-Strand Break Repair
## 191 RND1 GTPase cycle
## 192 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
## 193 Interleukin-38 signaling
## 194 RND2 GTPase cycle
## 195 RUNX1 regulates transcription of genes involved in differentiation of HSCs
## 196 Hemostasis
## 197 RHOF GTPase cycle
## 198 Epigenetic regulation of gene expression
## 199 Interleukin-36 pathway
## 200 G2 Phase
## 201 Transcriptional Regulation by VENTX
## 202 HATs acetylate histones
## 203 Oxidative Stress Induced Senescence
## 204 Pre-NOTCH Expression and Processing
## 205 Cellular responses to stress
## 206 G1 Phase
## 207 Cyclin D associated events in G1
## 208 RAC1 GTPase cycle
## 209 Gene Silencing by RNA
## 210 E2F-enabled inhibition of pre-replication complex formation
## 211 Signaling by Interleukins
## 212 Membrane Trafficking
## 213 Ub-specific processing proteases
## 214 E3 ubiquitin ligases ubiquitinate target proteins
## 215 Signaling by Nuclear Receptors
## 216 Interleukin-4 and Interleukin-13 signaling
## 217 SCF(Skp2)-mediated degradation of p27/p21
## 218 MASTL Facilitates Mitotic Progression
## 219 Autodegradation of Cdh1 by Cdh1:APC/C
## 220 Extension of Telomeres
## 221 FGFR2b ligand binding and activation
## 222 p53-Dependent G1/S DNA damage checkpoint
## 223 p53-Dependent G1 DNA Damage Response
## 224 G1/S DNA Damage Checkpoints
## 225 Orc1 removal from chromatin
## 226 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
## 227 Cholesterol biosynthesis
## 228 RHOG GTPase cycle
## 229 Hyaluronan uptake and degradation
## 230 Physiological factors
## 231 TP53 Regulates Transcription of Cell Death Genes
## 232 Interleukin-12 signaling
## 233 Interleukin-10 signaling
## 234 Regulation of TP53 Activity
## 235 Hyaluronan metabolism
## 236 E2F mediated regulation of DNA replication
## 237 Interleukin-12 family signaling
## 238 Generic Transcription Pathway
## 239 FGFR2 ligand binding and activation
## 240 Metabolism of Angiotensinogen to Angiotensins
## 241 Deubiquitination
## 242 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
## 243 NOTCH3 Activation and Transmission of Signal to the Nucleus
## 244 Vesicle-mediated transport
## 245 HDMs demethylate histones
## 246 Cilium Assembly
## 247 Antigen processing: Ubiquitination & Proteasome degradation
## 248 HCMV Early Events
## 249 TCF dependent signaling in response to WNT
## 250 Cytokine Signaling in Immune system
## 251 Apoptotic cleavage of cellular proteins
## 252 Signaling by WNT
## 253 RHOV GTPase cycle
## 254 Regulation of MECP2 expression and activity
## 255 Association of TriC/CCT with target proteins during biosynthesis
## 256 RNA Polymerase II Transcription
## 257 RND3 GTPase cycle
## 258 Regulation of TP53 Degradation
## 259 RHOU GTPase cycle
## 260 Regulation of TP53 Expression and Degradation
## 261 M-decay: degradation of maternal mRNAs by maternally stored factors
## 262 PKMTs methylate histone lysines
## 263 Chromatin organization
## 264 Chromatin modifying enzymes
## 265 Gene expression (Transcription)
## 266 Transcriptional regulation by RUNX1
## 267 Immune System
## 268 RMTs methylate histone arginines
## 269 DNA Repair
## 270 SCF-beta-TrCP mediated degradation of Emi1
## 271 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
## 272 Recycling pathway of L1
## 273 HCMV Infection
## 274 Negative regulation of NOTCH4 signaling
## 275 RHOJ GTPase cycle
## 276 SUMOylation of chromatin organization proteins
## 277 RHOQ GTPase cycle
## 278 NRAGE signals death through JNK
## 279 HCMV Late Events
## 280 Class I MHC mediated antigen processing & presentation
## 281 Interferon gamma signaling
## 282 Interleukin-1 family signaling
## 283 Activation of gene expression by SREBF (SREBP)
## 284 Aspirin ADME
## 285 Cell death signalling via NRAGE, NRIF and NADE
## 286 Peptide ligand-binding receptors
## 287 Nuclear Receptor transcription pathway
## 288 Integrin cell surface interactions
## 289 G alpha (12/13) signalling events
## 290 Organelle biogenesis and maintenance
## 291 Regulation of cholesterol biosynthesis by SREBP (SREBF)
## 292 Signaling by FGFR2
## 293 Signaling by NOTCH4
## 294 Chaperonin-mediated protein folding
## 295 Peptide chain elongation
## 296 PCP/CE pathway
## 297 Transcriptional Regulation by MECP2
## 298 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
## 299 Eukaryotic Translation Elongation
## 300 Protein folding
## 301 Eukaryotic Translation Termination
## 302 Formation of a pool of free 40S subunits
## 303 MAPK6/MAPK4 signaling
## 304 Transcriptional regulation of white adipocyte differentiation
## 305 Signaling by FGFR
## 306 p75 NTR receptor-mediated signalling
## 307 Selenocysteine synthesis
## 308 Viral mRNA Translation
## 309 Neddylation
## 310 Response of EIF2AK4 (GCN2) to amino acid deficiency
## 311 SRP-dependent cotranslational protein targeting to membrane
## 312 GTP hydrolysis and joining of the 60S ribosomal subunit
## 313 L13a-mediated translational silencing of Ceruloplasmin expression
## 314 Nonsense-Mediated Decay (NMD)
## 315 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
## 316 Interleukin-1 signaling
## 317 Post-translational protein modification
## 318 Eukaryotic Translation Initiation
## 319 Cap-dependent Translation Initiation
## 320 L1CAM interactions
## 321 Peptide hormone metabolism
## 322 Cardiac conduction
## 323 Transcriptional regulation by RUNX2
## 324 Toll Like Receptor 4 (TLR4) Cascade
## 325 Beta-catenin independent WNT signaling
## 326 Potential therapeutics for SARS
## 327 Metabolism of steroids
## 328 Death Receptor Signaling
## 329 Influenza Viral RNA Transcription and Replication
## 330 PPARA activates gene expression
## 331 Cellular response to starvation
## 332 Regulation of lipid metabolism by PPARalpha
## 333 Selenoamino acid metabolism
## 334 Regulation of expression of SLITs and ROBOs
## 335 Glycosaminoglycan metabolism
## 336 Major pathway of rRNA processing in the nucleolus and cytosol
## 337 Metabolism of proteins
## 338 Influenza Infection
## 339 Toll-like Receptor Cascades
## 340 rRNA processing in the nucleus and cytosol
## 341 Interferon Signaling
## 342 Class A/1 (Rhodopsin-like receptors)
## 343 Muscle contraction
## 344 Signaling by ROBO receptors
## 345 Drug ADME
## 346 rRNA processing
## 347 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
## 348 Cell surface interactions at the vascular wall
## 349 G alpha (q) signalling events
## 350 Phase I - Functionalization of compounds
## 351 Extracellular matrix organization
## 352 Viral Infection Pathways
## 353 Translation
## 354 Axon guidance
## 355 Developmental Biology
## 356 MAPK family signaling cascades
## 357 GPCR ligand binding
## 358 Nervous system development
## 359 G alpha (i) signalling events
## 360 Signaling by GPCR
## 361 Metabolism of carbohydrates
## 362 Neutrophil degranulation
## 363 Biological oxidations
## 364 GPCR downstream signalling
## 365 SARS-CoV Infections
## 366 Infectious disease
## 367 Disease
## 368 Signaling by Receptor Tyrosine Kinases
## 369 Metabolism of amino acids and derivatives
## 370 Metabolism of RNA
## 371 Metabolism of lipids
## 372 Innate Immune System
## 373 Metabolism
## X.Entities.found X.Entities.total Entities.ratio Entities.pValue
## 1 17 94 0.0061209872 1.110223e-16
## 2 17 94 0.0061209872 1.110223e-16
## 3 19 111 0.0072279742 1.110223e-16
## 4 11 23 0.0014976884 1.110223e-16
## 5 19 134 0.0087256626 1.110223e-16
## 6 23 211 0.0137396627 1.110223e-16
## 7 20 195 0.0126977925 1.110223e-16
## 8 53 595 0.0387445465 1.110223e-16
## 9 33 415 0.0270235072 1.110223e-16
## 10 54 733 0.0477306766 1.110223e-16
## 11 32 279 0.0181676109 1.110223e-16
## 12 17 121 0.0078791431 1.110223e-16
## 13 24 250 0.0162792212 1.110223e-16
## 14 24 249 0.0162141043 1.110223e-16
## 15 23 325 0.0211629876 1.110223e-15
## 16 31 708 0.0461027544 3.219647e-15
## 17 17 149 0.0097024158 4.440892e-15
## 18 31 724 0.0471446246 5.884182e-15
## 19 18 212 0.0138047796 9.436896e-14
## 20 18 214 0.0139350133 1.102451e-13
## 21 11 92 0.0059907534 2.274541e-10
## 22 11 92 0.0059907534 2.274541e-10
## 23 10 70 0.0045581819 2.848674e-10
## 24 10 77 0.0050140001 7.059421e-10
## 25 9 68 0.0044279482 4.396998e-09
## 26 7 32 0.0020837403 8.258845e-09
## 27 9 76 0.0049488832 1.135827e-08
## 28 11 153 0.0099628834 4.113641e-08
## 29 12 199 0.0129582601 6.477494e-08
## 30 6 26 0.0016930390 7.291993e-08
## 31 5 13 0.0008465195 7.639306e-08
## 32 9 107 0.0069675067 2.018117e-07
## 33 5 17 0.0011069870 2.849452e-07
## 34 4 7 0.0004558182 3.399332e-07
## 35 8 83 0.0054047014 3.573998e-07
## 36 5 21 0.0013674546 7.994630e-07
## 37 5 21 0.0013674546 7.994630e-07
## 38 10 168 0.0109396366 9.540370e-07
## 39 10 174 0.0113303380 1.303159e-06
## 40 7 74 0.0048186495 2.230245e-06
## 41 9 148 0.0096372990 2.865437e-06
## 42 10 194 0.0126326757 3.396007e-06
## 43 6 54 0.0035163118 4.900510e-06
## 44 6 54 0.0035163118 4.900510e-06
## 45 4 15 0.0009767533 6.829951e-06
## 46 8 134 0.0087256626 1.186381e-05
## 47 8 137 0.0089210132 1.389115e-05
## 48 6 65 0.0042325975 1.390302e-05
## 49 5 38 0.0024744416 1.395466e-05
## 50 4 20 0.0013023377 2.094579e-05
## 51 4 21 0.0013674546 2.530699e-05
## 52 6 73 0.0047535326 2.652071e-05
## 53 6 74 0.0048186495 2.859511e-05
## 54 6 74 0.0048186495 2.859511e-05
## 55 3 8 0.0005209351 3.793006e-05
## 56 4 24 0.0015628052 4.240050e-05
## 57 6 80 0.0052093508 4.395086e-05
## 58 3 9 0.0005860520 5.369904e-05
## 59 9 219 0.0142605978 6.148617e-05
## 60 4 27 0.0017581559 6.670349e-05
## 61 5 53 0.0034511949 6.710679e-05
## 62 5 53 0.0034511949 6.710679e-05
## 63 6 90 0.0058605196 8.364623e-05
## 64 7 131 0.0085303119 8.435224e-05
## 65 6 92 0.0059907534 9.423975e-05
## 66 7 135 0.0087907794 1.014915e-04
## 67 4 36 0.0023442079 1.997265e-04
## 68 3 15 0.0009767533 2.402607e-04
## 69 3 15 0.0009767533 2.402607e-04
## 70 4 38 0.0024744416 2.449916e-04
## 71 6 113 0.0073582080 2.834380e-04
## 72 40 3031 0.1973692779 3.190630e-04
## 73 3 17 0.0011069870 3.457953e-04
## 74 4 43 0.0028000260 3.898324e-04
## 75 7 179 0.0116559224 5.522258e-04
## 76 6 132 0.0085954288 6.389884e-04
## 77 4 50 0.0032558442 6.834239e-04
## 78 3 22 0.0014325715 7.284731e-04
## 79 5 94 0.0061209872 9.141044e-04
## 80 5 97 0.0063163378 1.050002e-03
## 81 4 57 0.0037116624 1.106990e-03
## 82 6 150 0.0097675327 1.228817e-03
## 83 6 153 0.0099628834 1.358040e-03
## 84 6 154 0.0100280003 1.403343e-03
## 85 4 61 0.0039721300 1.417737e-03
## 86 5 108 0.0070326236 1.679024e-03
## 87 3 30 0.0019535065 1.765348e-03
## 88 4 65 0.0042325975 1.784724e-03
## 89 4 68 0.0044279482 2.099861e-03
## 90 3 33 0.0021488572 2.310165e-03
## 91 3 33 0.0021488572 2.310165e-03
## 92 3 35 0.0022790910 2.725206e-03
## 93 4 75 0.0048837664 2.980627e-03
## 94 4 75 0.0048837664 2.980627e-03
## 95 3 38 0.0024744416 3.429206e-03
## 96 4 79 0.0051442339 3.582990e-03
## 97 4 79 0.0051442339 3.582990e-03
## 98 3 39 0.0025395585 3.686274e-03
## 99 3 39 0.0025395585 3.686274e-03
## 100 2 12 0.0007814026 4.100596e-03
## 101 3 41 0.0026697923 4.234964e-03
## 102 6 193 0.0125675588 4.259535e-03
## 103 4 83 0.0054047014 4.263182e-03
## 104 4 83 0.0054047014 4.263182e-03
## 105 3 44 0.0028651429 5.146589e-03
## 106 3 44 0.0028651429 5.146589e-03
## 107 4 88 0.0057302859 5.229633e-03
## 108 4 89 0.0057954027 5.439089e-03
## 109 3 45 0.0029302598 5.474635e-03
## 110 4 91 0.0059256365 5.874689e-03
## 111 3 47 0.0030604936 6.167742e-03
## 112 3 47 0.0030604936 6.167742e-03
## 113 3 48 0.0031256105 6.533038e-03
## 114 3 48 0.0031256105 6.533038e-03
## 115 2 16 0.0010418702 7.143320e-03
## 116 3 50 0.0032558442 7.301663e-03
## 117 3 50 0.0032558442 7.301663e-03
## 118 3 51 0.0033209611 7.705198e-03
## 119 2 17 0.0011069870 8.023340e-03
## 120 2 17 0.0011069870 8.023340e-03
## 121 4 100 0.0065116885 8.122485e-03
## 122 3 56 0.0036465455 9.918778e-03
## 123 9 460 0.0299537670 1.032925e-02
## 124 3 57 0.0037116624 1.040125e-02
## 125 2 20 0.0013023377 1.093748e-02
## 126 2 20 0.0013023377 1.093748e-02
## 127 2 20 0.0013023377 1.093748e-02
## 128 6 238 0.0154978186 1.131788e-02
## 129 3 60 0.0039070131 1.192946e-02
## 130 2 21 0.0013674546 1.199771e-02
## 131 3 61 0.0039721300 1.246599e-02
## 132 3 62 0.0040372469 1.301619e-02
## 133 4 116 0.0075535586 1.338216e-02
## 134 4 116 0.0075535586 1.338216e-02
## 135 3 63 0.0041023637 1.358009e-02
## 136 3 63 0.0041023637 1.358009e-02
## 137 9 484 0.0315165722 1.399610e-02
## 138 2 23 0.0014976884 1.424705e-02
## 139 2 23 0.0014976884 1.424705e-02
## 140 5 184 0.0119815068 1.514895e-02
## 141 3 66 0.0042977144 1.535448e-02
## 142 6 256 0.0166699225 1.567673e-02
## 143 3 67 0.0043628313 1.597363e-02
## 144 6 258 0.0168001563 1.622385e-02
## 145 2 25 0.0016279221 1.666342e-02
## 146 4 124 0.0080744937 1.667036e-02
## 147 15 1051 0.0684378459 1.729162e-02
## 148 3 70 0.0045581819 1.791457e-02
## 149 5 193 0.0125675588 1.821285e-02
## 150 3 71 0.0046232988 1.858947e-02
## 151 3 71 0.0046232988 1.858947e-02
## 152 4 130 0.0084651950 1.944161e-02
## 153 2 28 0.0018232728 2.058887e-02
## 154 3 75 0.0048837664 2.142906e-02
## 155 3 76 0.0049488832 2.217401e-02
## 156 4 137 0.0089210132 2.301557e-02
## 157 1 3 0.0001953507 2.317168e-02
## 158 2 30 0.0019535065 2.339847e-02
## 159 2 30 0.0019535065 2.339847e-02
## 160 3 79 0.0051442339 2.449305e-02
## 161 3 79 0.0051442339 2.449305e-02
## 162 3 80 0.0052093508 2.529411e-02
## 163 3 81 0.0052744677 2.610919e-02
## 164 4 144 0.0093768314 2.696515e-02
## 165 3 83 0.0054047014 2.778133e-02
## 166 2 33 0.0021488572 2.788854e-02
## 167 2 33 0.0021488572 2.788854e-02
## 168 3 84 0.0054698183 2.863837e-02
## 169 2 34 0.0022139741 2.945616e-02
## 170 3 86 0.0056000521 3.039428e-02
## 171 1 4 0.0002604675 3.077663e-02
## 172 1 4 0.0002604675 3.077663e-02
## 173 13 933 0.0607540535 3.086085e-02
## 174 3 88 0.0057302859 3.220582e-02
## 175 3 88 0.0057302859 3.220582e-02
## 176 3 88 0.0057302859 3.220582e-02
## 177 2 36 0.0023442079 3.269400e-02
## 178 2 36 0.0023442079 3.269400e-02
## 179 3 89 0.0057954027 3.313238e-02
## 180 3 90 0.0058605196 3.407277e-02
## 181 3 92 0.0059907534 3.599488e-02
## 182 2 38 0.0024744416 3.606457e-02
## 183 4 159 0.0103535847 3.672311e-02
## 184 1 5 0.0003255844 3.832285e-02
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## 191 2 43 0.0028000260 4.504023e-02
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## 195 3 105 0.0068372729 4.981056e-02
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## 199 1 7 0.0004558182 5.324095e-02
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## 203 3 113 0.0073582080 5.941785e-02
## 204 3 113 0.0073582080 5.941785e-02
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## 207 2 52 0.0033860780 6.298375e-02
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## 209 3 119 0.0077489093 6.715211e-02
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## 211 9 658 0.0428469102 7.330233e-02
## 212 9 668 0.0434980791 7.881703e-02
## 213 4 206 0.0134140783 7.884545e-02
## 214 2 60 0.0039070131 8.060057e-02
## 215 6 386 0.0251351175 8.298083e-02
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## 217 2 62 0.0040372469 8.521903e-02
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## 220 2 67 0.0043628313 9.710055e-02
## 221 1 14 0.0009116364 1.036697e-01
## 222 2 70 0.0045581819 1.044423e-01
## 223 2 70 0.0045581819 1.044423e-01
## 224 2 72 0.0046884157 1.094187e-01
## 225 2 73 0.0047535326 1.119303e-01
## 226 2 73 0.0047535326 1.119303e-01
## 227 2 77 0.0050140001 1.221233e-01
## 228 2 78 0.0050791170 1.247064e-01
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## 230 1 18 0.0011721039 1.312805e-01
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## 232 2 84 0.0054698183 1.404699e-01
## 233 2 86 0.0056000521 1.458170e-01
## 234 3 178 0.0115908055 1.634458e-01
## 235 1 23 0.0014976884 1.646106e-01
## 236 1 24 0.0015628052 1.711228e-01
## 237 2 96 0.0062512209 1.731309e-01
## 238 16 1586 0.1032753793 1.738934e-01
## 239 1 26 0.0016930390 1.839967e-01
## 240 1 26 0.0016930390 1.839967e-01
## 241 4 289 0.0188187797 1.907931e-01
## 242 1 28 0.0018232728 1.966722e-01
## 243 1 28 0.0018232728 1.966722e-01
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## 245 1 31 0.0020186234 2.153203e-01
## 246 3 209 0.0136094289 2.245760e-01
## 247 4 315 0.0205118187 2.330107e-01
## 248 3 215 0.0140001302 2.369103e-01
## 249 3 215 0.0140001302 2.369103e-01
## 250 11 1101 0.0716936902 2.421496e-01
## 251 1 38 0.0024744416 2.571796e-01
## 252 4 331 0.0215536889 2.600583e-01
## 253 1 39 0.0025395585 2.629759e-01
## 254 1 39 0.0025395585 2.629759e-01
## 255 1 40 0.0026046754 2.687273e-01
## 256 16 1728 0.1125219769 2.736598e-01
## 257 1 43 0.0028000260 2.857158e-01
## 258 1 43 0.0028000260 2.857158e-01
## 259 1 44 0.0028651429 2.912913e-01
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## 261 1 48 0.0031256105 3.131646e-01
## 262 1 48 0.0031256105 3.131646e-01
## 263 3 254 0.0165396887 3.191585e-01
## 264 3 254 0.0165396887 3.191585e-01
## 265 17 1917 0.1248290682 3.270204e-01
## 266 3 259 0.0168652732 3.298228e-01
## 267 23 2661 0.1732760305 3.324123e-01
## 268 1 52 0.0033860780 3.343684e-01
## 269 4 380 0.0247444162 3.457986e-01
## 270 1 55 0.0035814287 3.498440e-01
## 271 1 55 0.0035814287 3.498440e-01
## 272 1 55 0.0035814287 3.498440e-01
## 273 3 270 0.0175815589 3.532679e-01
## 274 1 57 0.0037116624 3.599623e-01
## 275 1 59 0.0038418962 3.699244e-01
## 276 1 62 0.0040372469 3.845799e-01
## 277 1 63 0.0041023637 3.893896e-01
## 278 1 64 0.0041674806 3.941620e-01
## 279 2 175 0.0113954548 3.976125e-01
## 280 4 412 0.0268281565 4.024464e-01
## 281 2 177 0.0115256886 4.030820e-01
## 282 2 183 0.0119163899 4.193491e-01
## 283 1 71 0.0046232988 4.265487e-01
## 284 1 80 0.0052093508 4.656777e-01
## 285 1 81 0.0052744677 4.698584e-01
## 286 2 203 0.0132187276 4.718813e-01
## 287 1 86 0.0056000521 4.902806e-01
## 288 1 86 0.0056000521 4.902806e-01
## 289 1 86 0.0056000521 4.902806e-01
## 290 3 337 0.0219443902 4.916543e-01
## 291 1 87 0.0056651690 4.942704e-01
## 292 1 88 0.0057302859 4.982293e-01
## 293 1 92 0.0059907534 5.137597e-01
## 294 1 96 0.0062512209 5.288134e-01
## 295 1 97 0.0063163378 5.325040e-01
## 296 1 99 0.0064465716 5.397994e-01
## 297 1 100 0.0065116885 5.434047e-01
## 298 1 101 0.0065768054 5.469820e-01
## 299 1 102 0.0066419223 5.505314e-01
## 300 1 102 0.0066419223 5.505314e-01
## 301 1 106 0.0069023898 5.644556e-01
## 302 1 106 0.0069023898 5.644556e-01
## 303 1 106 0.0069023898 5.644556e-01
## 304 1 109 0.0070977404 5.746172e-01
## 305 1 109 0.0070977404 5.746172e-01
## 306 1 110 0.0071628573 5.779519e-01
## 307 1 112 0.0072930911 5.845437e-01
## 308 1 114 0.0074233249 5.910334e-01
## 309 2 254 0.0165396887 5.920938e-01
## 310 1 115 0.0074884418 5.942404e-01
## 311 1 119 0.0077489093 6.068211e-01
## 312 1 120 0.0078140262 6.099054e-01
## 313 1 120 0.0078140262 6.099054e-01
## 314 1 124 0.0080744937 6.220042e-01
## 315 1 124 0.0080744937 6.220042e-01
## 316 1 125 0.0081396106 6.249703e-01
## 317 12 1637 0.1065963404 6.360301e-01
## 318 1 130 0.0084651950 6.394582e-01
## 319 1 130 0.0084651950 6.394582e-01
## 320 1 130 0.0084651950 6.394582e-01
## 321 1 130 0.0084651950 6.394582e-01
## 322 1 147 0.0095721821 6.846887e-01
## 323 1 147 0.0095721821 6.846887e-01
## 324 1 165 0.0107442860 7.264554e-01
## 325 1 166 0.0108094029 7.286077e-01
## 326 1 168 0.0109396366 7.328620e-01
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## 328 1 172 0.0112001042 7.411731e-01
## 329 1 173 0.0112652211 7.432105e-01
## 330 1 175 0.0113954548 7.472377e-01
## 331 1 176 0.0114605717 7.492277e-01
## 332 1 177 0.0115256886 7.512022e-01
## 333 1 180 0.0117210393 7.570337e-01
## 334 1 183 0.0119163899 7.627297e-01
## 335 1 183 0.0119163899 7.627297e-01
## 336 1 189 0.0123070912 7.737272e-01
## 337 15 2238 0.1457315882 7.765539e-01
## 338 1 198 0.0128931432 7.892827e-01
## 339 1 202 0.0131536107 7.958512e-01
## 340 1 207 0.0134791952 8.037770e-01
## 341 2 398 0.0259165202 8.205110e-01
## 342 2 414 0.0269583903 8.371759e-01
## 343 1 232 0.0151071173 8.390541e-01
## 344 1 235 0.0153024679 8.428400e-01
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## 346 1 247 0.0160838705 8.571206e-01
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## 348 1 257 0.0167350394 8.680323e-01
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## 350 1 297 0.0193397148 9.040090e-01
## 351 1 328 0.0213583382 9.250375e-01
## 352 5 1073 0.0698704174 9.276218e-01
## 353 1 339 0.0220746239 9.313428e-01
## 354 2 585 0.0380933776 9.455765e-01
## 355 7 1463 0.0952660025 9.462056e-01
## 356 1 380 0.0247444162 9.505446e-01
## 357 2 609 0.0396561828 9.536437e-01
## 358 2 621 0.0404375855 9.572393e-01
## 359 1 426 0.0277397929 9.658098e-01
## 360 3 876 0.0570423911 9.701146e-01
## 361 1 463 0.0301491177 9.746139e-01
## 362 1 478 0.0311258709 9.775051e-01
## 363 1 547 0.0356189360 9.871222e-01
## 364 2 795 0.0517679234 9.871832e-01
## 365 1 572 0.0372468581 9.894854e-01
## 366 5 1445 0.0940938985 9.903633e-01
## 367 11 2528 0.1646154848 9.924649e-01
## 368 1 625 0.0406980530 9.931666e-01
## 369 1 667 0.0434329622 9.951488e-01
## 370 1 841 0.0547633001 9.988389e-01
## 371 3 1463 0.0952660025 9.994376e-01
## 372 1 1341 0.0873217425 9.999827e-01
## 373 6 3662 0.2384580322 1.000000e+00
## Entities.FDR X.Reactions.found X.Reactions.total Reactions.ratio
## 1 2.997602e-15 4 4 2.762049e-04
## 2 2.997602e-15 4 4 2.762049e-04
## 3 2.997602e-15 7 7 4.833587e-04
## 4 2.997602e-15 13 15 1.035769e-03
## 5 2.997602e-15 6 8 5.524099e-04
## 6 2.997602e-15 15 20 1.381025e-03
## 7 2.997602e-15 6 8 5.524099e-04
## 8 2.997602e-15 204 352 2.430604e-02
## 9 2.997602e-15 50 91 6.283662e-03
## 10 2.997602e-15 237 451 3.114211e-02
## 11 2.997602e-15 23 56 3.866869e-03
## 12 2.997602e-15 2 5 3.452562e-04
## 13 2.997602e-15 10 33 2.278691e-03
## 14 2.997602e-15 9 32 2.209640e-03
## 15 2.775558e-14 15 113 7.802790e-03
## 16 7.727152e-14 59 203 1.401740e-02
## 17 9.769963e-14 3 27 1.864383e-03
## 18 1.235678e-13 59 212 1.463886e-02
## 19 1.887379e-12 65 78 5.385996e-03
## 20 2.094658e-12 67 80 5.524099e-03
## 21 3.866719e-09 38 40 2.762049e-03
## 22 3.866719e-09 38 40 2.762049e-03
## 23 4.557878e-09 4 18 1.242922e-03
## 24 1.129507e-08 15 15 1.035769e-03
## 25 6.595496e-08 8 14 9.667173e-04
## 26 1.156238e-07 20 25 1.726281e-03
## 27 1.590158e-07 13 13 8.976661e-04
## 28 5.347733e-07 14 24 1.657230e-03
## 29 8.420742e-07 17 90 6.214611e-03
## 30 8.750391e-07 3 3 2.071537e-04
## 31 9.167168e-07 3 12 8.286148e-04
## 32 2.421740e-06 2 11 7.595636e-04
## 33 3.134398e-06 1 2 1.381025e-04
## 34 3.739265e-06 2 2 1.381025e-04
## 35 3.931397e-06 13 14 9.667173e-04
## 36 7.195167e-06 3 3 2.071537e-04
## 37 7.195167e-06 2 2 1.381025e-04
## 38 8.586333e-06 25 58 4.004972e-03
## 39 1.172843e-05 37 101 6.974175e-03
## 40 2.007221e-05 6 6 4.143074e-04
## 41 2.292350e-05 2 18 1.242922e-03
## 42 2.716806e-05 9 43 2.969203e-03
## 43 3.920408e-05 10 10 6.905124e-04
## 44 3.920408e-05 4 57 3.935920e-03
## 45 5.463961e-05 4 4 2.762049e-04
## 46 9.491048e-05 23 34 2.347742e-03
## 47 9.723806e-05 1 26 1.795332e-03
## 48 9.732117e-05 7 42 2.900152e-03
## 49 9.768263e-05 8 27 1.864383e-03
## 50 1.466206e-04 2 2 1.381025e-04
## 51 1.715706e-04 4 11 7.595636e-04
## 52 1.715706e-04 3 3 2.071537e-04
## 53 1.715706e-04 6 6 4.143074e-04
## 54 1.715706e-04 2 2 1.381025e-04
## 55 2.275804e-04 2 2 1.381025e-04
## 56 2.544030e-04 3 3 2.071537e-04
## 57 2.637052e-04 7 12 8.286148e-04
## 58 3.221942e-04 2 4 2.762049e-04
## 59 3.689170e-04 2 48 3.314459e-03
## 60 4.002209e-04 3 7 4.833587e-04
## 61 4.026408e-04 4 4 2.762049e-04
## 62 4.026408e-04 4 4 2.762049e-04
## 63 4.182311e-04 8 22 1.519127e-03
## 64 4.217612e-04 18 32 2.209640e-03
## 65 4.711987e-04 9 12 8.286148e-04
## 66 5.074576e-04 12 38 2.623947e-03
## 67 9.986326e-04 2 3 2.071537e-04
## 68 1.201304e-03 5 5 3.452562e-04
## 69 1.201304e-03 2 4 2.762049e-04
## 70 1.224958e-03 2 5 3.452562e-04
## 71 1.417190e-03 10 23 1.588178e-03
## 72 1.595315e-03 107 2536 1.751139e-01
## 73 1.728977e-03 4 6 4.143074e-04
## 74 1.949162e-03 4 4 2.762049e-04
## 75 2.555954e-03 19 55 3.797818e-03
## 76 2.555954e-03 7 27 1.864383e-03
## 77 2.733696e-03 5 8 5.524099e-04
## 78 2.913892e-03 2 3 2.071537e-04
## 79 3.656418e-03 4 10 6.905124e-04
## 80 4.200009e-03 4 37 2.554896e-03
## 81 4.427958e-03 3 9 6.214611e-04
## 82 4.915270e-03 21 61 4.212125e-03
## 83 5.432162e-03 23 66 4.557382e-03
## 84 5.613371e-03 4 6 4.143074e-04
## 85 5.670947e-03 4 6 4.143074e-04
## 86 6.716096e-03 8 34 2.347742e-03
## 87 7.061393e-03 1 6 4.143074e-04
## 88 7.138897e-03 7 13 8.976661e-04
## 89 8.175619e-03 3 3 2.071537e-04
## 90 8.175619e-03 2 2 1.381025e-04
## 91 8.175619e-03 1 2 1.381025e-04
## 92 8.175619e-03 7 7 4.833587e-04
## 93 8.941881e-03 3 6 4.143074e-04
## 94 8.941881e-03 2 4 2.762049e-04
## 95 1.028762e-02 2 10 6.905124e-04
## 96 1.074897e-02 11 20 1.381025e-03
## 97 1.074897e-02 3 6 4.143074e-04
## 98 1.105882e-02 3 9 6.214611e-04
## 99 1.105882e-02 2 11 7.595636e-04
## 100 1.230179e-02 3 4 2.762049e-04
## 101 1.270489e-02 1 21 1.450076e-03
## 102 1.277861e-02 4 142 9.805276e-03
## 103 1.278955e-02 10 10 6.905124e-04
## 104 1.278955e-02 5 32 2.209640e-03
## 105 1.543977e-02 3 5 3.452562e-04
## 106 1.543977e-02 2 9 6.214611e-04
## 107 1.568890e-02 3 24 1.657230e-03
## 108 1.624497e-02 4 17 1.173871e-03
## 109 1.624497e-02 4 19 1.311973e-03
## 110 1.624497e-02 8 15 1.035769e-03
## 111 1.624497e-02 3 4 2.762049e-04
## 112 1.624497e-02 2 4 2.762049e-04
## 113 1.624497e-02 8 11 7.595636e-04
## 114 1.624497e-02 6 12 8.286148e-04
## 115 1.624497e-02 5 27 1.864383e-03
## 116 1.624497e-02 1 20 1.381025e-03
## 117 1.624497e-02 2 41 2.831101e-03
## 118 1.624497e-02 1 3 2.071537e-04
## 119 1.624497e-02 1 1 6.905124e-05
## 120 1.624497e-02 1 2 1.381025e-04
## 121 1.624497e-02 6 6 4.143074e-04
## 122 1.983756e-02 4 13 8.976661e-04
## 123 2.065849e-02 44 91 6.283662e-03
## 124 2.080250e-02 4 9 6.214611e-04
## 125 2.187496e-02 1 1 6.905124e-05
## 126 2.187496e-02 2 8 5.524099e-04
## 127 2.187496e-02 2 17 1.173871e-03
## 128 2.263576e-02 4 193 1.332689e-02
## 129 2.385891e-02 1 2 1.381025e-04
## 130 2.399543e-02 5 31 2.140588e-03
## 131 2.493199e-02 1 3 2.071537e-04
## 132 2.603237e-02 6 64 4.419279e-03
## 133 2.676431e-02 31 43 2.969203e-03
## 134 2.676431e-02 31 43 2.969203e-03
## 135 2.716018e-02 4 5 3.452562e-04
## 136 2.716018e-02 3 37 2.554896e-03
## 137 2.799220e-02 12 259 1.788427e-02
## 138 2.849410e-02 3 6 4.143074e-04
## 139 2.849410e-02 1 6 4.143074e-04
## 140 3.029790e-02 7 132 9.114763e-03
## 141 3.070895e-02 2 13 8.976661e-04
## 142 3.135347e-02 23 114 7.871841e-03
## 143 3.194725e-02 29 39 2.692998e-03
## 144 3.244769e-02 7 154 1.063389e-02
## 145 3.332684e-02 2 12 8.286148e-04
## 146 3.334072e-02 4 44 3.038254e-03
## 147 3.458324e-02 26 525 3.625190e-02
## 148 3.582914e-02 1 27 1.864383e-03
## 149 3.642571e-02 7 141 9.736224e-03
## 150 3.672311e-02 3 3 2.071537e-04
## 151 3.672311e-02 2 2 1.381025e-04
## 152 3.672311e-02 4 52 3.590664e-03
## 153 3.672311e-02 2 19 1.311973e-03
## 154 3.672311e-02 29 48 3.314459e-03
## 155 3.672311e-02 20 33 2.278691e-03
## 156 3.672311e-02 9 46 3.176357e-03
## 157 3.672311e-02 1 3 2.071537e-04
## 158 3.672311e-02 3 22 1.519127e-03
## 159 3.672311e-02 3 22 1.519127e-03
## 160 3.672311e-02 3 7 4.833587e-04
## 161 3.672311e-02 3 7 4.833587e-04
## 162 3.672311e-02 1 5 3.452562e-04
## 163 3.672311e-02 3 3 2.071537e-04
## 164 3.672311e-02 8 43 2.969203e-03
## 165 3.672311e-02 6 6 4.143074e-04
## 166 3.672311e-02 3 16 1.104820e-03
## 167 3.672311e-02 3 24 1.657230e-03
## 168 3.672311e-02 2 10 6.905124e-04
## 169 3.672311e-02 3 10 6.905124e-04
## 170 3.672311e-02 2 14 9.667173e-04
## 171 3.672311e-02 2 2 1.381025e-04
## 172 3.672311e-02 1 1 6.905124e-05
## 173 3.672311e-02 7 265 1.829858e-02
## 174 3.672311e-02 12 20 1.381025e-03
## 175 3.672311e-02 6 12 8.286148e-04
## 176 3.672311e-02 3 28 1.933435e-03
## 177 3.672311e-02 8 9 6.214611e-04
## 178 3.672311e-02 2 22 1.519127e-03
## 179 3.672311e-02 1 33 2.278691e-03
## 180 3.672311e-02 12 19 1.311973e-03
## 181 3.672311e-02 3 10 6.905124e-04
## 182 3.672311e-02 3 15 1.035769e-03
## 183 3.672311e-02 4 6 4.143074e-04
## 184 3.832285e-02 1 2 1.381025e-04
## 185 3.898085e-02 2 26 1.795332e-03
## 186 4.103955e-02 2 2 1.381025e-04
## 187 4.315228e-02 8 9 6.214611e-04
## 188 4.315228e-02 6 107 7.388482e-03
## 189 4.318466e-02 1 2 1.381025e-04
## 190 4.422314e-02 37 113 7.802790e-03
## 191 4.504023e-02 1 2 1.381025e-04
## 192 4.581081e-02 1 1 6.905124e-05
## 193 4.581081e-02 1 5 3.452562e-04
## 194 4.692489e-02 1 2 1.381025e-04
## 195 4.981056e-02 3 15 1.035769e-03
## 196 5.016551e-02 12 338 2.333932e-02
## 197 5.077924e-02 2 3 2.071537e-04
## 198 5.165589e-02 20 64 4.419279e-03
## 199 5.324095e-02 3 3 2.071537e-04
## 200 5.324095e-02 2 2 1.381025e-04
## 201 5.474332e-02 1 13 8.976661e-04
## 202 5.571913e-02 10 15 1.035769e-03
## 203 5.941785e-02 5 40 2.762049e-03
## 204 5.941785e-02 3 38 2.623947e-03
## 205 6.056518e-02 21 494 3.411131e-02
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## 211 7.330233e-02 22 505 3.487087e-02
## 212 7.881703e-02 2 219 1.512222e-02
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## 219 8.991588e-02 2 2 1.381025e-04
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## 221 1.036697e-01 2 3 2.071537e-04
## 222 1.044423e-01 2 22 1.519127e-03
## 223 1.044423e-01 2 22 1.519127e-03
## 224 1.094187e-01 2 26 1.795332e-03
## 225 1.119303e-01 1 4 2.762049e-04
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## 227 1.221233e-01 2 37 2.554896e-03
## 228 1.247064e-01 3 6 4.143074e-04
## 229 1.312805e-01 3 10 6.905124e-04
## 230 1.312805e-01 1 6 4.143074e-04
## 231 1.378128e-01 2 68 4.695484e-03
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## 233 1.458170e-01 1 15 1.035769e-03
## 234 1.634458e-01 3 98 6.767021e-03
## 235 1.646106e-01 3 13 8.976661e-04
## 236 1.711228e-01 1 4 2.762049e-04
## 237 1.731309e-01 1 114 7.871841e-03
## 238 1.738934e-01 40 884 6.104129e-02
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## 250 2.421496e-01 24 785 5.420522e-02
## 251 2.571796e-01 1 38 2.623947e-03
## 252 2.600583e-01 3 157 1.084104e-02
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## 264 3.191585e-01 24 85 5.869355e-03
## 265 3.270204e-01 63 1090 7.526585e-02
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## 267 3.324123e-01 35 1704 1.176633e-01
## 268 3.343684e-01 4 22 1.519127e-03
## 269 3.457986e-01 43 339 2.340837e-02
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## 271 3.498440e-01 3 6 4.143074e-04
## 272 3.498440e-01 2 14 9.667173e-04
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## 274 3.599623e-01 1 6 4.143074e-04
## 275 3.699244e-01 2 3 2.071537e-04
## 276 3.845799e-01 2 15 1.035769e-03
## 277 3.893896e-01 2 5 3.452562e-04
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## 279 3.976125e-01 1 19 1.311973e-03
## 280 4.024464e-01 5 48 3.314459e-03
## 281 4.030820e-01 2 23 1.588178e-03
## 282 4.193491e-01 18 92 6.352714e-03
## 283 4.265487e-01 1 42 2.900152e-03
## 284 4.656777e-01 1 26 1.795332e-03
## 285 4.698584e-01 1 17 1.173871e-03
## 286 4.718813e-01 2 83 5.731253e-03
## 287 4.902806e-01 2 2 1.381025e-04
## 288 4.902806e-01 6 55 3.797818e-03
## 289 4.902806e-01 1 15 1.035769e-03
## 290 4.916543e-01 8 86 5.938406e-03
## 291 4.942704e-01 1 52 3.590664e-03
## 292 4.982293e-01 2 46 3.176357e-03
## 293 5.137597e-01 1 20 1.381025e-03
## 294 5.288134e-01 1 19 1.311973e-03
## 295 5.325040e-01 4 5 3.452562e-04
## 296 5.397994e-01 1 24 1.657230e-03
## 297 5.434047e-01 1 77 5.316945e-03
## 298 5.469820e-01 1 1 6.905124e-05
## 299 5.505314e-01 4 9 6.214611e-04
## 300 5.505314e-01 1 28 1.933435e-03
## 301 5.644556e-01 3 5 3.452562e-04
## 302 5.644556e-01 1 2 1.381025e-04
## 303 5.644556e-01 3 40 2.762049e-03
## 304 5.746172e-01 10 19 1.311973e-03
## 305 5.746172e-01 2 142 9.805276e-03
## 306 5.779519e-01 1 50 3.452562e-03
## 307 5.845437e-01 2 7 4.833587e-04
## 308 5.910334e-01 2 2 1.381025e-04
## 309 5.920938e-01 7 44 3.038254e-03
## 310 5.942404e-01 4 16 1.104820e-03
## 311 6.068211e-01 5 5 3.452562e-04
## 312 6.099054e-01 2 3 2.071537e-04
## 313 6.099054e-01 1 3 2.071537e-04
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## 315 6.220042e-01 4 5 3.452562e-04
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## 319 6.394582e-01 3 18 1.242922e-03
## 320 6.394582e-01 2 54 3.728767e-03
## 321 6.394582e-01 1 65 4.488330e-03
## 322 6.846887e-01 1 33 2.278691e-03
## 323 6.846887e-01 1 84 5.800304e-03
## 324 7.264554e-01 1 107 7.388482e-03
## 325 7.286077e-01 1 51 3.521613e-03
## 326 7.328620e-01 1 36 2.485844e-03
## 327 7.409142e-01 3 251 1.733186e-02
## 328 7.411731e-01 1 119 8.217097e-03
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## 332 7.512022e-01 2 45 3.107306e-03
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## 334 7.627297e-01 2 20 1.381025e-03
## 335 7.627297e-01 3 88 6.076509e-03
## 336 7.737272e-01 1 7 4.833587e-04
## 337 7.765539e-01 42 823 5.682917e-02
## 338 7.892827e-01 2 59 4.074023e-03
## 339 7.958512e-01 1 198 1.367214e-02
## 340 8.037770e-01 1 15 1.035769e-03
## 341 8.205110e-01 2 119 8.217097e-03
## 342 8.371759e-01 2 185 1.277448e-02
## 343 8.390541e-01 1 53 3.659716e-03
## 344 8.428400e-01 2 60 4.143074e-03
## 345 8.477509e-01 1 121 8.355200e-03
## 346 8.571206e-01 1 21 1.450076e-03
## 347 8.593723e-01 1 44 3.038254e-03
## 348 8.680323e-01 3 65 4.488330e-03
## 349 8.943815e-01 3 35 2.416793e-03
## 350 9.040090e-01 1 102 7.043226e-03
## 351 9.250375e-01 6 319 2.202734e-02
## 352 9.276218e-01 9 651 4.495235e-02
## 353 9.313428e-01 16 99 6.836072e-03
## 354 9.455765e-01 4 298 2.057727e-02
## 355 9.462056e-01 55 719 4.964784e-02
## 356 9.505446e-01 3 122 8.424251e-03
## 357 9.536437e-01 2 217 1.498412e-02
## 358 9.572393e-01 4 324 2.237260e-02
## 359 9.658098e-01 3 74 5.109791e-03
## 360 9.701146e-01 9 392 2.706808e-02
## 361 9.746139e-01 3 241 1.664135e-02
## 362 9.775051e-01 3 10 6.905124e-04
## 363 9.871222e-01 1 192 1.325784e-02
## 364 9.871832e-01 7 175 1.208397e-02
## 365 9.894854e-01 1 401 2.768955e-02
## 366 9.903633e-01 9 897 6.193896e-02
## 367 9.924649e-01 15 1787 1.233946e-01
## 368 9.931666e-01 2 746 5.151222e-02
## 369 9.951488e-01 2 285 1.967960e-02
## 370 9.988389e-01 6 199 1.374120e-02
## 371 9.994376e-01 5 976 6.739401e-02
## 372 9.999827e-01 4 725 5.006215e-02
## 373 1.000000e+00 11 2283 1.576440e-01
## Species.identifier Species.name
## 1 9606 Homo sapiens
## 2 9606 Homo sapiens
## 3 9606 Homo sapiens
## 4 9606 Homo sapiens
## 5 9606 Homo sapiens
## 6 9606 Homo sapiens
## 7 9606 Homo sapiens
## 8 9606 Homo sapiens
## 9 9606 Homo sapiens
## 10 9606 Homo sapiens
## 11 9606 Homo sapiens
## 12 9606 Homo sapiens
## 13 9606 Homo sapiens
## 14 9606 Homo sapiens
## 15 9606 Homo sapiens
## 16 9606 Homo sapiens
## 17 9606 Homo sapiens
## 18 9606 Homo sapiens
## 19 9606 Homo sapiens
## 20 9606 Homo sapiens
## 21 9606 Homo sapiens
## 22 9606 Homo sapiens
## 23 9606 Homo sapiens
## 24 9606 Homo sapiens
## 25 9606 Homo sapiens
## 26 9606 Homo sapiens
## 27 9606 Homo sapiens
## 28 9606 Homo sapiens
## 29 9606 Homo sapiens
## 30 9606 Homo sapiens
## 31 9606 Homo sapiens
## 32 9606 Homo sapiens
## 33 9606 Homo sapiens
## 34 9606 Homo sapiens
## 35 9606 Homo sapiens
## 36 9606 Homo sapiens
## 37 9606 Homo sapiens
## 38 9606 Homo sapiens
## 39 9606 Homo sapiens
## 40 9606 Homo sapiens
## 41 9606 Homo sapiens
## 42 9606 Homo sapiens
## 43 9606 Homo sapiens
## 44 9606 Homo sapiens
## 45 9606 Homo sapiens
## 46 9606 Homo sapiens
## 47 9606 Homo sapiens
## 48 9606 Homo sapiens
## 49 9606 Homo sapiens
## 50 9606 Homo sapiens
## 51 9606 Homo sapiens
## 52 9606 Homo sapiens
## 53 9606 Homo sapiens
## 54 9606 Homo sapiens
## 55 9606 Homo sapiens
## 56 9606 Homo sapiens
## 57 9606 Homo sapiens
## 58 9606 Homo sapiens
## 59 9606 Homo sapiens
## 60 9606 Homo sapiens
## 61 9606 Homo sapiens
## 62 9606 Homo sapiens
## 63 9606 Homo sapiens
## 64 9606 Homo sapiens
## 65 9606 Homo sapiens
## 66 9606 Homo sapiens
## 67 9606 Homo sapiens
## 68 9606 Homo sapiens
## 69 9606 Homo sapiens
## 70 9606 Homo sapiens
## 71 9606 Homo sapiens
## 72 9606 Homo sapiens
## 73 9606 Homo sapiens
## 74 9606 Homo sapiens
## 75 9606 Homo sapiens
## 76 9606 Homo sapiens
## 77 9606 Homo sapiens
## 78 9606 Homo sapiens
## 79 9606 Homo sapiens
## 80 9606 Homo sapiens
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## 82 9606 Homo sapiens
## 83 9606 Homo sapiens
## 84 9606 Homo sapiens
## 85 9606 Homo sapiens
## 86 9606 Homo sapiens
## 87 9606 Homo sapiens
## 88 9606 Homo sapiens
## 89 9606 Homo sapiens
## 90 9606 Homo sapiens
## 91 9606 Homo sapiens
## 92 9606 Homo sapiens
## 93 9606 Homo sapiens
## 94 9606 Homo sapiens
## 95 9606 Homo sapiens
## 96 9606 Homo sapiens
## 97 9606 Homo sapiens
## 98 9606 Homo sapiens
## 99 9606 Homo sapiens
## 100 9606 Homo sapiens
## 101 9606 Homo sapiens
## 102 9606 Homo sapiens
## 103 9606 Homo sapiens
## 104 9606 Homo sapiens
## 105 9606 Homo sapiens
## 106 9606 Homo sapiens
## 107 9606 Homo sapiens
## 108 9606 Homo sapiens
## 109 9606 Homo sapiens
## 110 9606 Homo sapiens
## 111 9606 Homo sapiens
## 112 9606 Homo sapiens
## 113 9606 Homo sapiens
## 114 9606 Homo sapiens
## 115 9606 Homo sapiens
## 116 9606 Homo sapiens
## 117 9606 Homo sapiens
## 118 9606 Homo sapiens
## 119 9606 Homo sapiens
## 120 9606 Homo sapiens
## 121 9606 Homo sapiens
## 122 9606 Homo sapiens
## 123 9606 Homo sapiens
## 124 9606 Homo sapiens
## 125 9606 Homo sapiens
## 126 9606 Homo sapiens
## 127 9606 Homo sapiens
## 128 9606 Homo sapiens
## 129 9606 Homo sapiens
## 130 9606 Homo sapiens
## 131 9606 Homo sapiens
## 132 9606 Homo sapiens
## 133 9606 Homo sapiens
## 134 9606 Homo sapiens
## 135 9606 Homo sapiens
## 136 9606 Homo sapiens
## 137 9606 Homo sapiens
## 138 9606 Homo sapiens
## 139 9606 Homo sapiens
## 140 9606 Homo sapiens
## 141 9606 Homo sapiens
## 142 9606 Homo sapiens
## 143 9606 Homo sapiens
## 144 9606 Homo sapiens
## 145 9606 Homo sapiens
## 146 9606 Homo sapiens
## 147 9606 Homo sapiens
## 148 9606 Homo sapiens
## 149 9606 Homo sapiens
## 150 9606 Homo sapiens
## 151 9606 Homo sapiens
## 152 9606 Homo sapiens
## 153 9606 Homo sapiens
## 154 9606 Homo sapiens
## 155 9606 Homo sapiens
## 156 9606 Homo sapiens
## 157 9606 Homo sapiens
## 158 9606 Homo sapiens
## 159 9606 Homo sapiens
## 160 9606 Homo sapiens
## 161 9606 Homo sapiens
## 162 9606 Homo sapiens
## 163 9606 Homo sapiens
## 164 9606 Homo sapiens
## 165 9606 Homo sapiens
## 166 9606 Homo sapiens
## 167 9606 Homo sapiens
## 168 9606 Homo sapiens
## 169 9606 Homo sapiens
## 170 9606 Homo sapiens
## 171 9606 Homo sapiens
## 172 9606 Homo sapiens
## 173 9606 Homo sapiens
## 174 9606 Homo sapiens
## 175 9606 Homo sapiens
## 176 9606 Homo sapiens
## 177 9606 Homo sapiens
## 178 9606 Homo sapiens
## 179 9606 Homo sapiens
## 180 9606 Homo sapiens
## 181 9606 Homo sapiens
## 182 9606 Homo sapiens
## 183 9606 Homo sapiens
## 184 9606 Homo sapiens
## 185 9606 Homo sapiens
## 186 9606 Homo sapiens
## 187 9606 Homo sapiens
## 188 9606 Homo sapiens
## 189 9606 Homo sapiens
## 190 9606 Homo sapiens
## 191 9606 Homo sapiens
## 192 9606 Homo sapiens
## 193 9606 Homo sapiens
## 194 9606 Homo sapiens
## 195 9606 Homo sapiens
## 196 9606 Homo sapiens
## 197 9606 Homo sapiens
## 198 9606 Homo sapiens
## 199 9606 Homo sapiens
## 200 9606 Homo sapiens
## 201 9606 Homo sapiens
## 202 9606 Homo sapiens
## 203 9606 Homo sapiens
## 204 9606 Homo sapiens
## 205 9606 Homo sapiens
## 206 9606 Homo sapiens
## 207 9606 Homo sapiens
## 208 9606 Homo sapiens
## 209 9606 Homo sapiens
## 210 9606 Homo sapiens
## 211 9606 Homo sapiens
## 212 9606 Homo sapiens
## 213 9606 Homo sapiens
## 214 9606 Homo sapiens
## 215 9606 Homo sapiens
## 216 9606 Homo sapiens
## 217 9606 Homo sapiens
## 218 9606 Homo sapiens
## 219 9606 Homo sapiens
## 220 9606 Homo sapiens
## 221 9606 Homo sapiens
## 222 9606 Homo sapiens
## 223 9606 Homo sapiens
## 224 9606 Homo sapiens
## 225 9606 Homo sapiens
## 226 9606 Homo sapiens
## 227 9606 Homo sapiens
## 228 9606 Homo sapiens
## 229 9606 Homo sapiens
## 230 9606 Homo sapiens
## 231 9606 Homo sapiens
## 232 9606 Homo sapiens
## 233 9606 Homo sapiens
## 234 9606 Homo sapiens
## 235 9606 Homo sapiens
## 236 9606 Homo sapiens
## 237 9606 Homo sapiens
## 238 9606 Homo sapiens
## 239 9606 Homo sapiens
## 240 9606 Homo sapiens
## 241 9606 Homo sapiens
## 242 9606 Homo sapiens
## 243 9606 Homo sapiens
## 244 9606 Homo sapiens
## 245 9606 Homo sapiens
## 246 9606 Homo sapiens
## 247 9606 Homo sapiens
## 248 9606 Homo sapiens
## 249 9606 Homo sapiens
## 250 9606 Homo sapiens
## 251 9606 Homo sapiens
## 252 9606 Homo sapiens
## 253 9606 Homo sapiens
## 254 9606 Homo sapiens
## 255 9606 Homo sapiens
## 256 9606 Homo sapiens
## 257 9606 Homo sapiens
## 258 9606 Homo sapiens
## 259 9606 Homo sapiens
## 260 9606 Homo sapiens
## 261 9606 Homo sapiens
## 262 9606 Homo sapiens
## 263 9606 Homo sapiens
## 264 9606 Homo sapiens
## 265 9606 Homo sapiens
## 266 9606 Homo sapiens
## 267 9606 Homo sapiens
## 268 9606 Homo sapiens
## 269 9606 Homo sapiens
## 270 9606 Homo sapiens
## 271 9606 Homo sapiens
## 272 9606 Homo sapiens
## 273 9606 Homo sapiens
## 274 9606 Homo sapiens
## 275 9606 Homo sapiens
## 276 9606 Homo sapiens
## 277 9606 Homo sapiens
## 278 9606 Homo sapiens
## 279 9606 Homo sapiens
## 280 9606 Homo sapiens
## 281 9606 Homo sapiens
## 282 9606 Homo sapiens
## 283 9606 Homo sapiens
## 284 9606 Homo sapiens
## 285 9606 Homo sapiens
## 286 9606 Homo sapiens
## 287 9606 Homo sapiens
## 288 9606 Homo sapiens
## 289 9606 Homo sapiens
## 290 9606 Homo sapiens
## 291 9606 Homo sapiens
## 292 9606 Homo sapiens
## 293 9606 Homo sapiens
## 294 9606 Homo sapiens
## 295 9606 Homo sapiens
## 296 9606 Homo sapiens
## 297 9606 Homo sapiens
## 298 9606 Homo sapiens
## 299 9606 Homo sapiens
## 300 9606 Homo sapiens
## 301 9606 Homo sapiens
## 302 9606 Homo sapiens
## 303 9606 Homo sapiens
## 304 9606 Homo sapiens
## 305 9606 Homo sapiens
## 306 9606 Homo sapiens
## 307 9606 Homo sapiens
## 308 9606 Homo sapiens
## 309 9606 Homo sapiens
## 310 9606 Homo sapiens
## 311 9606 Homo sapiens
## 312 9606 Homo sapiens
## 313 9606 Homo sapiens
## 314 9606 Homo sapiens
## 315 9606 Homo sapiens
## 316 9606 Homo sapiens
## 317 9606 Homo sapiens
## 318 9606 Homo sapiens
## 319 9606 Homo sapiens
## 320 9606 Homo sapiens
## 321 9606 Homo sapiens
## 322 9606 Homo sapiens
## 323 9606 Homo sapiens
## 324 9606 Homo sapiens
## 325 9606 Homo sapiens
## 326 9606 Homo sapiens
## 327 9606 Homo sapiens
## 328 9606 Homo sapiens
## 329 9606 Homo sapiens
## 330 9606 Homo sapiens
## 331 9606 Homo sapiens
## 332 9606 Homo sapiens
## 333 9606 Homo sapiens
## 334 9606 Homo sapiens
## 335 9606 Homo sapiens
## 336 9606 Homo sapiens
## 337 9606 Homo sapiens
## 338 9606 Homo sapiens
## 339 9606 Homo sapiens
## 340 9606 Homo sapiens
## 341 9606 Homo sapiens
## 342 9606 Homo sapiens
## 343 9606 Homo sapiens
## 344 9606 Homo sapiens
## 345 9606 Homo sapiens
## 346 9606 Homo sapiens
## 347 9606 Homo sapiens
## 348 9606 Homo sapiens
## 349 9606 Homo sapiens
## 350 9606 Homo sapiens
## 351 9606 Homo sapiens
## 352 9606 Homo sapiens
## 353 9606 Homo sapiens
## 354 9606 Homo sapiens
## 355 9606 Homo sapiens
## 356 9606 Homo sapiens
## 357 9606 Homo sapiens
## 358 9606 Homo sapiens
## 359 9606 Homo sapiens
## 360 9606 Homo sapiens
## 361 9606 Homo sapiens
## 362 9606 Homo sapiens
## 363 9606 Homo sapiens
## 364 9606 Homo sapiens
## 365 9606 Homo sapiens
## 366 9606 Homo sapiens
## 367 9606 Homo sapiens
## 368 9606 Homo sapiens
## 369 9606 Homo sapiens
## 370 9606 Homo sapiens
## 371 9606 Homo sapiens
## 372 9606 Homo sapiens
## 373 9606 Homo sapiens
## Submitted.entities.found
## 1 PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 2 PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 3 UBE2C;PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;UBE2S;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 4 CCNB2;CCNB1;CENPF;WEE1;PLK1;CDC25C
## 5 PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;CCNB2;SGOL2;CENPF;KIF18A;CCNB1;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 6 PLK4;PLK1;CASC5;NCAPG;BUB1B;CDCA8;CENPA;SMC4;NDC80;SKA1;CDC20;CENPE;CCNB2;SGOL2;CENPF;KIF18A;CCNB1;NUF2;BIRC5;KIF2C;NEK2;BUB1;MAD2L1
## 7 UBE2C;PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;PTTG1;UBE2S;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 8 CDKN1C;TOP2A;CASC5;NCAPG;BUB1B;CDCA8;HMMR;CENPA;SMC4;SKA1;LMNB1;AURKA;CDC20;CCNB2;CCNB1;SGOL2;PTTG1;NUF2;NEK2;BUB1;LBR;GTSE1;PLK4;GINS2;UBE2C;PLK1;KIF23;CDC25C;NDC80;CCNA2;TPX2;CENPE;KIF18A;CENPF;WEE1;DBF4;CCNE2;UBE2S;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;KIF20A;MCM6;HIST1H4C;MAD2L1
## 9 CDCA8;CASC5;NCAPG;BUB1B;CENPA;SMC4;SKA1;LMNB1;CDC20;CCNB2;CCNB1;SGOL2;PTTG1;NUF2;NEK2;BUB1;LBR;PLK4;UBE2C;PLK1;KIF23;NDC80;CENPE;CENPF;KIF18A;UBE2S;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;KIF20A;HIST1H4C;MAD2L1
## 10 CDKN1C;TOP2A;PIF1;CASC5;NCAPG;BUB1B;CDCA8;HMMR;CENPA;SMC4;SKA1;LMNB1;AURKA;CDC20;CCNB2;CCNB1;SGOL2;PTTG1;NUF2;NEK2;BUB1;LBR;GTSE1;PLK4;GINS2;UBE2C;PLK1;KIF23;CDC25C;NDC80;CCNA2;TPX2;CENPE;KIF18A;CENPF;WEE1;DBF4;CCNE2;UBE2S;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;KIF20A;MCM6;HIST1H4C;MAD2L1
## 11 CDCA8;CASC5;BUB1B;CENPA;SKA1;CDC20;CCNB2;CCNB1;SGOL2;NUF2;BUB1;GTSE1;UBE2C;PLK1;CDC25C;NDC80;CCNA2;CENPE;CENPF;KIF18A;WEE1;DBF4;CCNE2;UBE2S;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;MCM6;HIST1H4C;MAD2L1
## 12 PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 13 UBE2C;PLK1;CDCA8;CASC5;BUB1B;CENPA;NDC80;SKA1;LMNB1;CDC20;CENPE;CCNB2;CENPF;KIF18A;CCNB1;SGOL2;PTTG1;UBE2S;NUF2;BIRC5;KIF2C;BUB1;LBR;MAD2L1
## 14 UBE2C;PLK1;CDCA8;CASC5;BUB1B;CENPA;NDC80;SKA1;LMNB1;CDC20;CENPE;CCNB2;CENPF;KIF18A;CCNB1;SGOL2;PTTG1;UBE2S;NUF2;BIRC5;KIF2C;BUB1;LBR;MAD2L1
## 15 PLK1;KIF14;CASC5;BUB1B;CDCA8;CDC25C;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;PRC1;NUF2;BIRC5;HIST1H4H;HIST1H2BH;KIF2C;HIST1H4C;BUB1;MAD2L1
## 16 ARHGAP11A;KIF14;CDCA8;CASC5;BUB1B;CENPA;SKA1;LMNB1;CDC20;SGOL2;RACGAP1;NUF2;RAC3;ECT2;BUB1;LBR;PLK1;CDC25C;NDC80;CENPE;ANLN;CENPF;KIF18A;DEPDC1B;PRC1;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;HIST1H4C;MAD2L1
## 17 PLK1;CASC5;BUB1B;CDCA8;CENPA;NDC80;SKA1;CDC20;CENPE;SGOL2;CENPF;KIF18A;NUF2;BIRC5;KIF2C;BUB1;MAD2L1
## 18 ARHGAP11A;KIF14;CDCA8;CASC5;BUB1B;CENPA;SKA1;LMNB1;CDC20;SGOL2;RACGAP1;NUF2;RAC3;ECT2;BUB1;LBR;PLK1;CDC25C;NDC80;CENPE;ANLN;CENPF;KIF18A;DEPDC1B;PRC1;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;HIST1H4C;MAD2L1
## 19 PLK4;PLK1;HMMR;CDC25C;AURKA;CCNA2;TPX2;CCNB2;WEE1;CCNB1;CENPF;NEK2;GTSE1
## 20 PLK4;PLK1;HMMR;CDC25C;AURKA;CCNA2;TPX2;CCNB2;WEE1;CCNB1;CENPF;NEK2;GTSE1
## 21 CDC20;CCNA2;CCNB1;PTTG1;UBE2C;UBE2S;PLK1;BUB1B;NEK2;BUB1;AURKA;MAD2L1
## 22 CDC20;CCNA2;CCNB1;PTTG1;UBE2C;UBE2S;PLK1;BUB1B;NEK2;BUB1;AURKA;MAD2L1
## 23 CCNA2;CCNE2;HIST1H1D;HIST1H1E;HIST1H4H;HIST1H2BH;HIST1H4C;HIST1H1A;HIST1H1B;LMNB1
## 24 CDC20;CCNA2;CCNB1;PTTG1;UBE2C;UBE2S;PLK1;BUB1B;NEK2;BUB1;MAD2L1
## 25 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 26 CCNA2;CCNB2;WEE1;CCNB1;PLK1;CDC25C
## 27 CDC20;CCNA2;CCNB1;PTTG1;UBE2C;UBE2S;BUB1B;NEK2;BUB1;MAD2L1
## 28 CCNB2;WEE1;CCNB1;DBF4;HIST1H4H;HIST1H2BH;MCM6;CDC25C;HIST1H4C;GTSE1
## 29 CCNA2;CCNE2;UBE2C;UBE2S;HIST1H1D;HIST1H1E;HIST1H4H;HIST1H2BH;HIST1H4C;HIST1H1A;HIST1H1B;LMNB1
## 30 CDC20;UBE2C;UBE2S;BUB1B;NEK2;BUB1;MAD2L1
## 31 HIST1H1D;HMGB2;HIST1H1E;HIST1H1A;HIST1H1B
## 32 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 33 HIST1H1D;HIST1H1E;HIST1H1A;HIST1H1B;LMNB1
## 34 CCNB2;WEE1;CCNB1
## 35 CDC20;CCNA2;CCNB1;UBE2C;UBE2S;PLK1;BUB1B;BUB1;MAD2L1
## 36 CDC20;UBE2C;UBE2S;BUB1B;BUB1;MAD2L1
## 37 CDC20;UBE2C;UBE2S;BUB1B;BUB1;MAD2L1
## 38 CCNA2;GINS2;DBF4;CCNE2;UBE2C;UBE2S;HIST1H4H;HIST1H2BH;MCM6;HIST1H4C
## 39 TOP2A;CCNA2;CDKN1C;WEE1;CCNB1;DBF4;CCNE2;MCM6
## 40 CDC20;CCNA2;UBE2C;UBE2S;BUB1B;NEK2;BUB1;MAD2L1
## 41 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 42 CENPE;KIF18A;WEE1;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 43 CCNB1;PLK1;HIST1H4H;HIST1H2BH;HIST1H4C;SMC4
## 44 HIST1H1D;HMGB2;HIST1H1E;HIST1H1A;HIST1H1B;LMNB1
## 45 CCNB2;CCNB1;NCAPG;SMC4
## 46 CCNB2;CCNB1;PLK1;HIST1H4H;HIST1H2BH;HIST1H4C;SMC4;LMNB1
## 47 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11
## 48 CCNA2;CCNB1;CCNE2;CDC25C;AURKA
## 49 TOP2A;CCNA2;CCNE2
## 50 CCNB1;UBE2C;UBE2S;PLK1
## 51 CCNB1;CDC25C;AURKA
## 52 CDC20;CCNA2;UBE2C;UBE2S;BUB1B;BUB1;MAD2L1
## 53 CDC20;PTTG1;UBE2C;UBE2S;PLK1;AURKA
## 54 PLK4;TPX2;PLK1;NEK2;HMMR;AURKA
## 55 CDC20;CCNB1;PLK1
## 56 CDC20;CCNB1;UBE2C;UBE2S
## 57 WEE1;CCNB1;HIST1H4H;HIST1H2BH;CDC25C;HIST1H4C
## 58 CCNB2;CCNB1;PLK1
## 59 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 60 CCNB2;CCNB1;LBR;LMNB1
## 61 CASC5;HIST1H4H;HIST1H2BH;HIST1H4C;CENPA
## 62 CASC5;HIST1H4H;HIST1H2BH;HIST1H4C;CENPA
## 63 CCNA2;UBE2C;UBE2S;HIST1H4H;HIST1H2BH;HIST1H4C
## 64 DBF4;UBE2C;UBE2S;HIST1H4H;HIST1H2BH;MCM6;HIST1H4C
## 65 PLK4;CCNB2;CCNB1;PLK1;NEK2;AURKA
## 66 CCNA2;PIF1;CASC5;HIST1H4H;HIST1H2BH;HIST1H4C;CENPA
## 67 CDKN1C;CCNE2;UBE2C;UBE2S
## 68 WEE1;CCNB1;CDC25C
## 69 PLK1;KIF23;KIF20A
## 70 CDKN1C;CCNE2;UBE2C;UBE2S
## 71 UBE2C;UBE2S;HIST1H4H;HIST1H2BH;MCM6;HIST1H4C
## 72 ARHGAP11A;KIF14;CDCA8;CASC5;BUB1B;CXXC5;CENPA;SKA1;LMNB1;CDC20;SGOL2;RACGAP1;NUF2;RAC3;ECT2;BUB1;LBR;DLGAP5;FGFBP1;PLK1;CDC25C;NDC80;CENPE;ANLN;DARC;CENPF;KIF18A;DEPDC1B;PRC1;NMU;TACC3;HIST1H4H;BIRC5;HIST1H2BH;KIF2C;HIST1H4C;MAD2L1
## 73 CCNB2;CCNB1;PLK1
## 74 HIST1H4H;HIST1H2BH;HIST1H4C;PHF19
## 75 CCNA2;GINS2;WEE1;CCNE2;UBE2C;UBE2S;MCM6
## 76 CCNA2;GINS2;CCNE2;UBE2C;UBE2S;MCM6
## 77 TOP2A;BIRC5;CDCA8;AURKA
## 78 CDC20;UBE2C;UBE2S
## 79 CCNA2;CCNE2;UBE2C;UBE2S;MCM6
## 80 HIST1H4H;HIST1H2BH;CDC25C;HIST1H4C;LMNB1
## 81 DEPDC1B;RACGAP1;LBR;LMNB1
## 82 CCNA2;WEE1;CCNB1;DBF4;CCNE2;MCM6
## 83 HIST1H4H;RAC3;HIST1H2BH;CXXC5;HIST1H4C
## 84 ARHGAP11A;ANLN;DEPDC1B;RACGAP1;ECT2;LBR
## 85 HIST1H4H;HIST1H2BH;HIST1H4C;LMNB1
## 86 CCNA2;PIF1;HIST1H4H;HIST1H2BH;HIST1H4C
## 87 HIST1H4H;HIST1H2BH;HIST1H4C
## 88 CCNB2;CCNB1;PLK1;LMNB1
## 89 CDC20;PTTG1;UBE2C;UBE2S
## 90 HIST1H4H;HIST1H2BH;HIST1H4C
## 91 HIST1H4H;HIST1H2BH;HIST1H4C
## 92 HIST1H4H;HIST1H2BH;HIST1H4C
## 93 ANLN;DEPDC1B;RACGAP1;ECT2
## 94 CCNA2;CCNE2;UBE2C;UBE2S
## 95 HIST1H4H;HIST1H2BH;HIST1H4C
## 96 HIST1H4H;HIST1H2BH;CDC25C;HIST1H4C
## 97 ANLN;DEPDC1B;RACGAP1;LBR
## 98 DBF4;MCM6;CDC25C
## 99 HIST1H4H;HIST1H2BH;HIST1H4C
## 100 GINS2;MCM6
## 101 HIST1H4H;HIST1H2BH;HIST1H4C
## 102 HIST1H1D;HMGB2;HIST1H1E;HIST1H1A;HIST1H1B;LMNB1
## 103 CCNB2;CCNB1;PLK1;GTSE1
## 104 UBE2C;UBE2S;HIST1H2BH
## 105 HIST1H4H;HIST1H2BH;HIST1H4C
## 106 HIST1H4H;HIST1H2BH;HIST1H4C
## 107 CCNB2;CCNB1;LBR;LMNB1
## 108 CCNA2;HIST1H4H;HIST1H2BH;HIST1H4C
## 109 HIST1H4H;HIST1H2BH;HIST1H4C
## 110 HIST1H4H;HIST1H2BH;HIST1H4C;LMNB1
## 111 HIST1H4H;HIST1H2BH;HIST1H4C
## 112 HIST1H4H;HIST1H2BH;HIST1H4C
## 113 HIST1H4H;HIST1H2BH;HIST1H4C
## 114 HIST1H4H;HIST1H2BH;HIST1H4C
## 115 CES1;MT1E
## 116 HIST1H4H;HIST1H2BH;HIST1H4C
## 117 HIST1H4H;HIST1H2BH;HIST1H4C
## 118 HIST1H4H;HIST1H2BH;HIST1H4C
## 119 CDKN1C;CCNE2
## 120 CDKN1C;CCNE2
## 121 DEPDC1B;RACGAP1;RAC3;LBR
## 122 HIST1H4H;HIST1H2BH;HIST1H4C
## 123 ARHGAP11A;ANLN;DEPDC1B;RACGAP1;KIF14;RAC3;ECT2;LBR;LMNB1
## 124 HIST1H4H;HIST1H2BH;HIST1H4C
## 125 UBE2C;UBE2S
## 126 CCNA2
## 127 CCNA2;CCNE2
## 128 HIST1H1D;HMGB2;HIST1H1E;HIST1H1A;HIST1H1B;LMNB1
## 129 HIST1H4H;HIST1H2BH;HIST1H4C
## 130 CES1;MT1E
## 131 HIST1H4H;HIST1H2BH;HIST1H4C
## 132 HIST1H4H;HIST1H2BH;HIST1H4C
## 133 HIST1H4H;RAC3;HIST1H2BH;HIST1H4C
## 134 HIST1H4H;RAC3;HIST1H2BH;HIST1H4C
## 135 HIST1H4H;HIST1H2BH;HIST1H4C
## 136 TACC3;DLGAP5
## 137 CCNA2;TPX2;CCNB1;CCNE2;BIRC5;CDC25C;AURKA
## 138 CCNB1;LMNB1
## 139 PRC1;KIF14
## 140 TOP2A;BIRC5;HIST1H4H;CDCA8;HIST1H4C;AURKA
## 141 HIST1H4H;HIST1H2BH;HIST1H4C
## 142 HIST1H4H;RAC3;HIST1H2BH;CXXC5;HIST1H4C
## 143 HIST1H4H;HIST1H2BH;HIST1H4C
## 144 TACC3;HIST1H4H;HIST1H2BH;HIST1H4C;DLGAP5
## 145 TOP2A
## 146 CCNA2;HIST1H4H;HIST1H2BH;HIST1H4C
## 147 UBE2C;LMNB1;CCNA2;CCNE2;UBE2S;HIST1H1D;HIST1H1E;HIST1H4H;HIST1H2BH;RPL22L1;HIST1H4C;HIST1H1A;HIST1H1B;CES1;MT1E
## 148 HIST1H4H;HIST1H2BH;HIST1H4C
## 149 TOP2A;BIRC5;HIST1H4H;CDCA8;HIST1H4C;AURKA
## 150 PLK4;PLK1;NEK2
## 151 PLK4;PLK1;NEK2
## 152 CCNA2;HIST1H4H;HIST1H2BH;HIST1H4C
## 153 BIRC5
## 154 HIST1H4H;HIST1H2BH;HIST1H4C
## 155 HIST1H4H;HIST1H2BH;HIST1H4C
## 156 HIST1H4H;BIRC5;HIST1H2BH;HIST1H4C
## 157 LMNB1
## 158 CDC25C;LMNB1
## 159 CDC25C;LMNB1
## 160 HIST1H4H;HIST1H2BH;HIST1H4C
## 161 HIST1H4H;HIST1H2BH;HIST1H4C
## 162 HIST1H4H;HIST1H2BH;HIST1H4C
## 163 PLK4;PLK1;NEK2
## 164 HIST1H4H;HIST1H2BH;HIST1H4C;LMNB1
## 165 PLK4;PLK1;NEK2
## 166 UBE2C;UBE2S
## 167 CDC25C;LMNB1
## 168 HIST1H4H;HIST1H2BH;HIST1H4C
## 169 CCNA2;PIF1
## 170 HIST1H4H;HIST1H2BH;HIST1H4C
## 171 AURKA
## 172 PLK1
## 173 UBE2C;CCNF;ITGB2;KIF23;KIF11;CDC20;CENPE;KIF18A;RACGAP1;UBE2S;KIF4A;KIF2C;KIF20A
## 174 CCNA2;WEE1;CCNE2
## 175 HIST1H4H;HIST1H2BH;HIST1H4C
## 176 HIST1H4H;HIST1H2BH;HIST1H4C
## 177 DBF4;MCM6
## 178 DLGAP5
## 179 HIST1H4H;HIST1H2BH;HIST1H4C
## 180 CCNA2;WEE1;CCNE2
## 181 DEPDC1B;RACGAP1;LBR
## 182 GINS2;MCM6
## 183 DEPDC1B;RACGAP1;ECT2;LBR
## 184 CCNA2
## 185 CCNA2;TPX2;AURKA
## 186 PLK4;PLK1;NEK2
## 187 PLK4;PLK1;NEK2
## 188 HIST1H4H;HIST1H2BH;HIST1H4C
## 189 CCNB2;CCNB1
## 190 CCNA2;HIST1H4H;HIST1H2BH;HIST1H4C
## 191 DEPDC1B;KIF14
## 192 CCNE2
## 193 IL1R1
## 194 DEPDC1B;KIF14
## 195 HIST1H4H;HIST1H2BH;HIST1H4C
## 196 CENPE;KIF18A;WEE1;RACGAP1;KIF4A;ITGB2;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 197 DEPDC1B;LMNB1
## 198 HIST1H4H;HIST1H2BH;HIST1H4C;PHF19
## 199 IL1R1
## 200 CCNA2
## 201 UBE2C;UBE2S
## 202 HIST1H4H;HIST1H2BH;HIST1H4C
## 203 HIST1H4H;HIST1H2BH;HIST1H4C
## 204 HIST1H4H;HIST1H2BH;HIST1H4C
## 205 UBE2C;LMNB1;CCNA2;CCNE2;UBE2S;HIST1H1D;HIST1H1E;HIST1H4H;HIST1H2BH;RPL22L1;HIST1H4C;HIST1H1A;HIST1H1B
## 206 CDKN1C;CCNE2
## 207 CDKN1C;CCNE2
## 208 DEPDC1B;RACGAP1;ECT2;LBR
## 209 HIST1H4H;HIST1H2BH;HIST1H4C
## 210 CCNB1
## 211 IL1R1;ITGB2;BIRC5;LMNB1
## 212 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 213 CDC20;CCNA2;HIST1H2BH
## 214 HIST1H2BH
## 215 HIST1H4H;RAC3;HIST1H2BH;CXXC5;HIST1H4C
## 216 ITGB2;BIRC5
## 217 CCNA2;CCNE2
## 218 CCNB1
## 219 UBE2C;UBE2S
## 220 CCNA2;PIF1
## 221 FGFBP1
## 222 CCNA2;CCNE2
## 223 CCNA2;CCNE2
## 224 CCNA2;CCNE2
## 225 CCNA2;MCM6
## 226 LMNB1
## 227 LBR
## 228 DEPDC1B;LBR
## 229 HMMR
## 230 CES1
## 231 BIRC5
## 232 LMNB1
## 233 IL1R1
## 234 CCNA2;TPX2;AURKA
## 235 HMMR
## 236 CCNB1
## 237 LMNB1
## 238 UBE2C;CDC25C;AURKA;CCNA2;TPX2;CCNB1;CCNE2;UBE2S;BIRC5;HIST1H4H;HIST1H2BH;HIST1H4C;LBR;CEP55
## 239 FGFBP1
## 240 CES1
## 241 CDC20;CCNA2;HIST1H2BH
## 242 CDC25C
## 243 TACC3
## 244 CENPE;KIF18A;RACGAP1;KIF4A;KIF23;KIF2C;KIF20A;KIF11;KIF20B
## 245 HIST1H4H;HIST1H4C
## 246 PLK4;PLK1;NEK2
## 247 CDC20;UBE2C;UBE2S;CCNF
## 248 HIST1H4H;HIST1H2BH;HIST1H4C
## 249 HIST1H4H;HIST1H2BH;HIST1H4C
## 250 IL1R1;ITGB2;BIRC5;CES1;LMNB1
## 251 LMNB1
## 252 HIST1H4H;RAC3;HIST1H2BH;HIST1H4C
## 253 DEPDC1B
## 254 LBR
## 255 CCNE2
## 256 UBE2C;CDC25C;AURKA;CCNA2;TPX2;CCNB1;CCNE2;UBE2S;BIRC5;HIST1H4H;HIST1H2BH;HIST1H4C;LBR;CEP55
## 257 DEPDC1B
## 258 CCNA2
## 259 DEPDC1B
## 260 CCNA2
## 261 BIRC5
## 262 HIST1H4H;HIST1H4C
## 263 HIST1H4H;HIST1H2BH;HIST1H4C
## 264 HIST1H4H;HIST1H2BH;HIST1H4C
## 265 UBE2C;CDC25C;AURKA;CCNA2;TPX2;CCNB1;CCNE2;UBE2S;BIRC5;HIST1H4H;HIST1H2BH;HIST1H4C;LBR;CEP55;PHF19
## 266 HIST1H4H;HIST1H2BH;HIST1H4C
## 267 UBE2C;IL1R1;CCNF;ITGB2;KIF23;KIF11;LMNB1;CDC20;CENPE;KIF18A;RACGAP1;UBE2S;KIF4A;BIRC5;KIF2C;KIF20A;CES1
## 268 HIST1H4H;HIST1H4C
## 269 CCNA2;HIST1H4H;HIST1H2BH;HIST1H4C
## 270 CDC20
## 271 AURKA
## 272 KIF4A
## 273 HIST1H4H;HIST1H2BH;HIST1H4C
## 274 TACC3
## 275 DEPDC1B
## 276 HIST1H4H;HIST1H4C
## 277 DEPDC1B
## 278 ECT2
## 279 HIST1H4H;HIST1H2BH;HIST1H4C
## 280 CDC20;UBE2C;UBE2S;CCNF
## 281 CES1
## 282 IL1R1
## 283 LBR
## 284 CES1
## 285 ECT2
## 286 DARC;NMU
## 287 CEP55
## 288 ITGB2
## 289 ECT2
## 290 PLK4;PLK1;NEK2
## 291 LBR
## 292 FGFBP1
## 293 TACC3
## 294 CCNE2
## 295 RPL22L1
## 296 RAC3
## 297 LBR
## 298 RPL22L1
## 299 RPL22L1
## 300 CCNE2
## 301 RPL22L1
## 302 RPL22L1
## 303 RAC3
## 304 RAC3
## 305 FGFBP1
## 306 ECT2
## 307 RPL22L1
## 308 RPL22L1
## 309 CCNF;BIRC5
## 310 RPL22L1
## 311 RPL22L1
## 312 RPL22L1
## 313 RPL22L1
## 314 RPL22L1
## 315 RPL22L1
## 316 IL1R1
## 317 CDC20;TOP2A;CCNA2;UBE2C;UBE2S;CCNF;BIRC5;HIST1H4H;CDCA8;HIST1H2BH;HIST1H4C;AURKA
## 318 RPL22L1
## 319 RPL22L1
## 320 KIF4A
## 321 CES1
## 322 CES1
## 323 CCNB1
## 324 ITGB2
## 325 RAC3
## 326 IL1R1
## 327 LBR
## 328 ECT2
## 329 RPL22L1
## 330 RAC3
## 331 RPL22L1
## 332 RAC3
## 333 RPL22L1
## 334 RPL22L1
## 335 HMMR
## 336 RPL22L1
## 337 TOP2A;UBE2C;CCNF;CDCA8;AURKA;CDC20;CCNA2;CCNE2;UBE2S;BIRC5;HIST1H4H;HIST1H2BH;RPL22L1;HIST1H4C;CES1
## 338 RPL22L1
## 339 ITGB2
## 340 RPL22L1
## 341 CES1
## 342 DARC;NMU
## 343 CES1
## 344 RPL22L1
## 345 CES1
## 346 RPL22L1
## 347 ITGB2
## 348 ITGB2
## 349 NMU
## 350 CES1
## 351 ITGB2
## 352 IL1R1;HIST1H4H;HIST1H2BH;RPL22L1;HIST1H4C
## 353 RPL22L1
## 354 KIF4A;RPL22L1
## 355 KIF4A;HIST1H4H;RAC3;BIRC5;HIST1H2BH;RPL22L1;HIST1H4C
## 356 RAC3
## 357 DARC;NMU
## 358 KIF4A;RPL22L1
## 359 NMU
## 360 DARC;NMU;ECT2
## 361 HMMR
## 362 ITGB2
## 363 CES1
## 364 NMU;ECT2
## 365 IL1R1
## 366 IL1R1;HIST1H4H;HIST1H2BH;RPL22L1;HIST1H4C
## 367 CDKN1C;CCNE2;UBE2C;UBE2S;IL1R1;HIST1H4H;HIST1H2BH;RPL22L1;CDC25C;HIST1H4C;LMNB1
## 368 FGFBP1
## 369 RPL22L1
## 370 RPL22L1
## 371 RAC3;LBR
## 372 ITGB2
## 373 RAC3;RPL22L1;HMMR;LBR;CES1
## Mapped.entities
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 NA
## 6 NA
## 7 NA
## 8 NA
## 9 NA
## 10 NA
## 11 NA
## 12 NA
## 13 NA
## 14 NA
## 15 NA
## 16 NA
## 17 NA
## 18 NA
## 19 NA
## 20 NA
## 21 NA
## 22 NA
## 23 NA
## 24 NA
## 25 NA
## 26 NA
## 27 NA
## 28 NA
## 29 NA
## 30 NA
## 31 NA
## 32 NA
## 33 NA
## 34 NA
## 35 NA
## 36 NA
## 37 NA
## 38 NA
## 39 NA
## 40 NA
## 41 NA
## 42 NA
## 43 NA
## 44 NA
## 45 NA
## 46 NA
## 47 NA
## 48 NA
## 49 NA
## 50 NA
## 51 NA
## 52 NA
## 53 NA
## 54 NA
## 55 NA
## 56 NA
## 57 NA
## 58 NA
## 59 NA
## 60 NA
## 61 NA
## 62 NA
## 63 NA
## 64 NA
## 65 NA
## 66 NA
## 67 NA
## 68 NA
## 69 NA
## 70 NA
## 71 NA
## 72 NA
## 73 NA
## 74 NA
## 75 NA
## 76 NA
## 77 NA
## 78 NA
## 79 NA
## 80 NA
## 81 NA
## 82 NA
## 83 NA
## 84 NA
## 85 NA
## 86 NA
## 87 NA
## 88 NA
## 89 NA
## 90 NA
## 91 NA
## 92 NA
## 93 NA
## 94 NA
## 95 NA
## 96 NA
## 97 NA
## 98 NA
## 99 NA
## 100 NA
## 101 NA
## 102 NA
## 103 NA
## 104 NA
## 105 NA
## 106 NA
## 107 NA
## 108 NA
## 109 NA
## 110 NA
## 111 NA
## 112 NA
## 113 NA
## 114 NA
## 115 NA
## 116 NA
## 117 NA
## 118 NA
## 119 NA
## 120 NA
## 121 NA
## 122 NA
## 123 NA
## 124 NA
## 125 NA
## 126 NA
## 127 NA
## 128 NA
## 129 NA
## 130 NA
## 131 NA
## 132 NA
## 133 NA
## 134 NA
## 135 NA
## 136 NA
## 137 NA
## 138 NA
## 139 NA
## 140 NA
## 141 NA
## 142 NA
## 143 NA
## 144 NA
## 145 NA
## 146 NA
## 147 NA
## 148 NA
## 149 NA
## 150 NA
## 151 NA
## 152 NA
## 153 NA
## 154 NA
## 155 NA
## 156 NA
## 157 NA
## 158 NA
## 159 NA
## 160 NA
## 161 NA
## 162 NA
## 163 NA
## 164 NA
## 165 NA
## 166 NA
## 167 NA
## 168 NA
## 169 NA
## 170 NA
## 171 NA
## 172 NA
## 173 NA
## 174 NA
## 175 NA
## 176 NA
## 177 NA
## 178 NA
## 179 NA
## 180 NA
## 181 NA
## 182 NA
## 183 NA
## 184 NA
## 185 NA
## 186 NA
## 187 NA
## 188 NA
## 189 NA
## 190 NA
## 191 NA
## 192 NA
## 193 NA
## 194 NA
## 195 NA
## 196 NA
## 197 NA
## 198 NA
## 199 NA
## 200 NA
## 201 NA
## 202 NA
## 203 NA
## 204 NA
## 205 NA
## 206 NA
## 207 NA
## 208 NA
## 209 NA
## 210 NA
## 211 NA
## 212 NA
## 213 NA
## 214 NA
## 215 NA
## 216 NA
## 217 NA
## 218 NA
## 219 NA
## 220 NA
## 221 NA
## 222 NA
## 223 NA
## 224 NA
## 225 NA
## 226 NA
## 227 NA
## 228 NA
## 229 NA
## 230 NA
## 231 NA
## 232 NA
## 233 NA
## 234 NA
## 235 NA
## 236 NA
## 237 NA
## 238 NA
## 239 NA
## 240 NA
## 241 NA
## 242 NA
## 243 NA
## 244 NA
## 245 NA
## 246 NA
## 247 NA
## 248 NA
## 249 NA
## 250 NA
## 251 NA
## 252 NA
## 253 NA
## 254 NA
## 255 NA
## 256 NA
## 257 NA
## 258 NA
## 259 NA
## 260 NA
## 261 NA
## 262 NA
## 263 NA
## 264 NA
## 265 NA
## 266 NA
## 267 NA
## 268 NA
## 269 NA
## 270 NA
## 271 NA
## 272 NA
## 273 NA
## 274 NA
## 275 NA
## 276 NA
## 277 NA
## 278 NA
## 279 NA
## 280 NA
## 281 NA
## 282 NA
## 283 NA
## 284 NA
## 285 NA
## 286 NA
## 287 NA
## 288 NA
## 289 NA
## 290 NA
## 291 NA
## 292 NA
## 293 NA
## 294 NA
## 295 NA
## 296 NA
## 297 NA
## 298 NA
## 299 NA
## 300 NA
## 301 NA
## 302 NA
## 303 NA
## 304 NA
## 305 NA
## 306 NA
## 307 NA
## 308 NA
## 309 NA
## 310 NA
## 311 NA
## 312 NA
## 313 NA
## 314 NA
## 315 NA
## 316 NA
## 317 NA
## 318 NA
## 319 NA
## 320 NA
## 321 NA
## 322 NA
## 323 NA
## 324 NA
## 325 NA
## 326 NA
## 327 NA
## 328 NA
## 329 NA
## 330 NA
## 331 NA
## 332 NA
## 333 NA
## 334 NA
## 335 NA
## 336 NA
## 337 NA
## 338 NA
## 339 NA
## 340 NA
## 341 NA
## 342 NA
## 343 NA
## 344 NA
## 345 NA
## 346 NA
## 347 NA
## 348 NA
## 349 NA
## 350 NA
## 351 NA
## 352 NA
## 353 NA
## 354 NA
## 355 NA
## 356 NA
## 357 NA
## 358 NA
## 359 NA
## 360 NA
## 361 NA
## 362 NA
## 363 NA
## 364 NA
## 365 NA
## 366 NA
## 367 NA
## 368 NA
## 369 NA
## 370 NA
## 371 NA
## 372 NA
## 373 NA
## Found.reaction.identifiers
## 1 R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439
## 2 R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439
## 3 R-HSA-141409;R-HSA-141431;R-HSA-141429;R-HSA-141422;R-HSA-141439;R-HSA-141423;R-HSA-141437
## 4 R-HSA-162657;R-HSA-156678;R-HSA-4088441;R-HSA-4088439;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-4088305;R-HSA-4088298;R-HSA-4088299;R-HSA-4088134;R-HSA-156699;R-HSA-4088130
## 5 R-HSA-2468293;R-HSA-2466068;R-HSA-2484822;R-HSA-1638803;R-HSA-2468287;R-HSA-1638821
## 6 R-HSA-2514854;R-HSA-2468293;R-HSA-9648114;R-HSA-375302;R-HSA-156682;R-HSA-1638803;R-HSA-2529015;R-HSA-2466068;R-HSA-2484822;R-HSA-2520883;R-HSA-380316;R-HSA-380508;R-HSA-2529020;R-HSA-2468287;R-HSA-1638821
## 7 R-HSA-174144;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121
## 8 R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-156682;R-HSA-174088;R-HSA-187916;R-HSA-156699;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-380455;R-HSA-187937;R-HSA-174119;R-HSA-9018017;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-170044;R-HSA-2245218;R-HSA-174144;R-HSA-170055;R-HSA-69191;R-HSA-4088441;R-HSA-4088439;R-HSA-69195;R-HSA-170057;R-HSA-9624798;R-HSA-174159;R-HSA-69199;R-HSA-174157;R-HSA-170070;R-HSA-174164;R-HSA-174171;R-HSA-380508;R-HSA-170072;R-HSA-8942803;R-HSA-174174;R-HSA-170076;R-HSA-2430533;R-HSA-170087;R-HSA-170084;R-HSA-69227;R-HSA-170088;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-8942836;R-HSA-69756;R-HSA-141437;R-HSA-187520;R-HSA-174209;R-HSA-170116;R-HSA-8942607;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-174235;R-HSA-8854044;R-HSA-174238;R-HSA-2995376;R-HSA-8854041;R-HSA-187552;R-HSA-170149;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-174255;R-HSA-170159;R-HSA-5244669;R-HSA-170156;R-HSA-170161;R-HSA-187574;R-HSA-4086410;R-HSA-187575;R-HSA-163010;R-HSA-174273;R-HSA-5229194;R-HSA-5195402;R-HSA-2993898;R-HSA-157906;R-HSA-179410;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-2172666;R-HSA-179421;R-HSA-4088024;R-HSA-2172194;R-HSA-8852354;R-HSA-8852362;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-2294580;R-HSA-8853405;R-HSA-188191;R-HSA-2294590;R-HSA-2172678;R-HSA-9686969;R-HSA-176942;R-HSA-8853419;R-HSA-2984220;R-HSA-2466068;R-HSA-2429719;R-HSA-8853429;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2301205;R-HSA-68919;R-HSA-2172183;R-HSA-68918;R-HSA-8964531;R-HSA-176956;R-HSA-8853444;R-HSA-68940;R-HSA-68944;R-HSA-9686980;R-HSA-68954;R-HSA-9648114;R-HSA-68960;R-HSA-162657;R-HSA-8964588;R-HSA-2314566;R-HSA-1363314;R-HSA-2294600;R-HSA-8964580;R-HSA-1363303;R-HSA-380278;R-HSA-380272;R-HSA-4088134;R-HSA-1363311;R-HSA-1226094;R-HSA-4088130;R-HSA-1226095;R-HSA-1363306;R-HSA-380283;R-HSA-8853496;R-HSA-2514854;R-HSA-380294;R-HSA-3002798;R-HSA-1638803;R-HSA-380303;R-HSA-69005;R-HSA-380311;R-HSA-69015;R-HSA-3002811;R-HSA-380316;R-HSA-2468287;R-HSA-69019;R-HSA-69562;R-HSA-1638821;R-HSA-188350;R-HSA-8852280;R-HSA-2288097;R-HSA-2467809;R-HSA-2467811;R-HSA-4088309;R-HSA-4088306;R-HSA-8852298;R-HSA-4088307;R-HSA-4088305;R-HSA-188371;R-HSA-3000319;R-HSA-8941915;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-8852317;R-HSA-2574845;R-HSA-3000310;R-HSA-2574840;R-HSA-188386;R-HSA-2468293;R-HSA-8852324;R-HSA-188390;R-HSA-174054;R-HSA-113638;R-HSA-174058;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-2467798;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-8852351;R-HSA-2562526;R-HSA-174079;R-HSA-169468
## 9 R-HSA-2514854;R-HSA-375302;R-HSA-156673;R-HSA-2172194;R-HSA-156682;R-HSA-1638803;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-2294580;R-HSA-380316;R-HSA-2468287;R-HSA-2294590;R-HSA-2995376;R-HSA-2172678;R-HSA-174121;R-HSA-5244669;R-HSA-2984220;R-HSA-2466068;R-HSA-156723;R-HSA-2429719;R-HSA-2301205;R-HSA-2172183;R-HSA-1638821;R-HSA-2245218;R-HSA-163010;R-HSA-174144;R-HSA-2288097;R-HSA-2467809;R-HSA-5229194;R-HSA-5195402;R-HSA-2467811;R-HSA-2993898;R-HSA-9624798;R-HSA-2529015;R-HSA-380508;R-HSA-2529020;R-HSA-2172666;R-HSA-2468293;R-HSA-2430533;R-HSA-9648114;R-HSA-2314566;R-HSA-2294600;R-HSA-2214351;R-HSA-9624800;R-HSA-2484822;R-HSA-2467798;R-HSA-380278;R-HSA-174202
## 10 R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-156682;R-HSA-174088;R-HSA-187916;R-HSA-912408;R-HSA-156699;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-75809;R-HSA-380455;R-HSA-187937;R-HSA-174119;R-HSA-9018017;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-176700;R-HSA-170044;R-HSA-2245218;R-HSA-5683735;R-HSA-174144;R-HSA-170055;R-HSA-69191;R-HSA-606287;R-HSA-912458;R-HSA-4088441;R-HSA-4088439;R-HSA-69195;R-HSA-170057;R-HSA-9624798;R-HSA-174159;R-HSA-69199;R-HSA-174157;R-HSA-912450;R-HSA-170070;R-HSA-174164;R-HSA-606289;R-HSA-174171;R-HSA-380508;R-HSA-170072;R-HSA-912470;R-HSA-8942803;R-HSA-174174;R-HSA-912467;R-HSA-170076;R-HSA-2430533;R-HSA-141409;R-HSA-170087;R-HSA-170084;R-HSA-69227;R-HSA-170088;R-HSA-141422;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-141431;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-912503;R-HSA-8942836;R-HSA-141439;R-HSA-912496;R-HSA-69756;R-HSA-141437;R-HSA-606326;R-HSA-187520;R-HSA-174209;R-HSA-606349;R-HSA-170116;R-HSA-8942607;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-9670149;R-HSA-174235;R-HSA-8854044;R-HSA-174238;R-HSA-2995376;R-HSA-8854041;R-HSA-187552;R-HSA-170149;R-HSA-176298;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-174255;R-HSA-170159;R-HSA-5244669;R-HSA-170156;R-HSA-170161;R-HSA-187574;R-HSA-4086410;R-HSA-187575;R-HSA-176318;R-HSA-163010;R-HSA-174273;R-HSA-5229194;R-HSA-5195402;R-HSA-2993898;R-HSA-181450;R-HSA-157906;R-HSA-179410;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-2172666;R-HSA-179421;R-HSA-4088024;R-HSA-1214188;R-HSA-69891;R-HSA-75010;R-HSA-2172194;R-HSA-8852354;R-HSA-75016;R-HSA-8852362;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-75028;R-HSA-2294580;R-HSA-8853405;R-HSA-163096;R-HSA-188191;R-HSA-2294590;R-HSA-2172678;R-HSA-9686969;R-HSA-176942;R-HSA-8853419;R-HSA-2984220;R-HSA-2466068;R-HSA-2429719;R-HSA-8853429;R-HSA-163120;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2301205;R-HSA-68919;R-HSA-2172183;R-HSA-68918;R-HSA-8964531;R-HSA-176956;R-HSA-8853444;R-HSA-9670101;R-HSA-68940;R-HSA-68944;R-HSA-9686980;R-HSA-68954;R-HSA-9648114;R-HSA-68960;R-HSA-162657;R-HSA-8964588;R-HSA-2314566;R-HSA-1363314;R-HSA-9686521;R-HSA-2294600;R-HSA-8964580;R-HSA-9670114;R-HSA-1363303;R-HSA-380278;R-HSA-380272;R-HSA-4088134;R-HSA-1363311;R-HSA-1226094;R-HSA-4088130;R-HSA-1226095;R-HSA-1363306;R-HSA-380283;R-HSA-8853496;R-HSA-2514854;R-HSA-380294;R-HSA-3002798;R-HSA-1638803;R-HSA-380303;R-HSA-69005;R-HSA-380311;R-HSA-69015;R-HSA-3002811;R-HSA-380316;R-HSA-2468287;R-HSA-69019;R-HSA-69562;R-HSA-1638821;R-HSA-188350;R-HSA-8852280;R-HSA-2288097;R-HSA-2467809;R-HSA-2467811;R-HSA-4088309;R-HSA-4088306;R-HSA-8852298;R-HSA-4088307;R-HSA-4088305;R-HSA-188371;R-HSA-3000319;R-HSA-8941915;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-8852317;R-HSA-2574845;R-HSA-3000310;R-HSA-2574840;R-HSA-188386;R-HSA-2468293;R-HSA-8852324;R-HSA-188390;R-HSA-174054;R-HSA-113638;R-HSA-174058;R-HSA-9029987;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-2467798;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-8852351;R-HSA-2562526;R-HSA-174079;R-HSA-169468
## 11 R-HSA-75809;R-HSA-5683735;R-HSA-69891;R-HSA-141409;R-HSA-75010;R-HSA-8852354;R-HSA-170055;R-HSA-176298;R-HSA-75016;R-HSA-9029987;R-HSA-141422;R-HSA-141423;R-HSA-170070;R-HSA-141431;R-HSA-75028;R-HSA-8852337;R-HSA-141429;R-HSA-8852351;R-HSA-69562;R-HSA-176318;R-HSA-187934;R-HSA-141439;R-HSA-141437
## 12 R-HSA-9648114;R-HSA-156682
## 13 R-HSA-163010;R-HSA-174144;R-HSA-9624800;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121;R-HSA-9624798;R-HSA-2995376
## 14 R-HSA-174144;R-HSA-9624800;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-174121;R-HSA-9624798;R-HSA-2995376
## 15 R-HSA-5666160;R-HSA-5666129;R-HSA-75016;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883;R-HSA-5666169;R-HSA-5671737;R-HSA-5625797;R-HSA-5625796;R-HSA-5671749;R-HSA-5671970;R-HSA-5625870;R-HSA-5625774
## 16 R-HSA-9013004;R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-8981637;R-HSA-5625797;R-HSA-9013145;R-HSA-9013144;R-HSA-5625796;R-HSA-9714694;R-HSA-5671749;R-HSA-9013023;R-HSA-9013022;R-HSA-9714691;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-9692809;R-HSA-9696271;R-HSA-9693198;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-9714481;R-HSA-5666160;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-5625849;R-HSA-9013157;R-HSA-5625848;R-HSA-9714361;R-HSA-9013159;R-HSA-5666169;R-HSA-9018808;R-HSA-9013437;R-HSA-9691174;R-HSA-9013438;R-HSA-9014449;R-HSA-9018804;R-HSA-9018807;R-HSA-9018806;R-HSA-9014467;R-HSA-5625883;R-HSA-9693125;R-HSA-8980691;R-HSA-5625870;R-HSA-5625784;R-HSA-5671737;R-HSA-9018745;R-HSA-9693282;R-HSA-9018746;R-HSA-5671970;R-HSA-5625774;R-HSA-9013111;R-HSA-9013110
## 17 R-HSA-5666160;R-HSA-5666129;R-HSA-5666169
## 18 R-HSA-9013004;R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-8981637;R-HSA-5625797;R-HSA-9013145;R-HSA-9013144;R-HSA-5625796;R-HSA-9714694;R-HSA-5671749;R-HSA-9013023;R-HSA-9013022;R-HSA-9714691;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-9692809;R-HSA-9696271;R-HSA-9693198;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-9714481;R-HSA-5666160;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-5625849;R-HSA-9013157;R-HSA-5625848;R-HSA-9714361;R-HSA-9013159;R-HSA-5666169;R-HSA-9018808;R-HSA-9013437;R-HSA-9691174;R-HSA-9013438;R-HSA-9014449;R-HSA-9018804;R-HSA-9018807;R-HSA-9018806;R-HSA-9014467;R-HSA-5625883;R-HSA-9693125;R-HSA-8980691;R-HSA-5625870;R-HSA-5625784;R-HSA-5671737;R-HSA-9018745;R-HSA-9693282;R-HSA-9018746;R-HSA-5671970;R-HSA-5625774;R-HSA-9013111;R-HSA-9013110
## 19 R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-8854044;R-HSA-8854041;R-HSA-380455;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-8853429;R-HSA-170161;R-HSA-4086410;R-HSA-170044;R-HSA-8852280;R-HSA-8853444;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-8852298;R-HSA-4088307;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-8852317;R-HSA-2574845;R-HSA-170072;R-HSA-3000310;R-HSA-170076;R-HSA-2574840;R-HSA-8852324;R-HSA-162657;R-HSA-170087;R-HSA-4088024;R-HSA-170084;R-HSA-170088;R-HSA-8852331;R-HSA-380272;R-HSA-8852337;R-HSA-8852351;R-HSA-4088134;R-HSA-2562526;R-HSA-4088130;R-HSA-69756;R-HSA-380283;R-HSA-8853496
## 20 R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-8854044;R-HSA-8854041;R-HSA-380455;R-HSA-187937;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-8853429;R-HSA-170161;R-HSA-4086410;R-HSA-187959;R-HSA-170044;R-HSA-8852280;R-HSA-8853444;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-8852298;R-HSA-4088307;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-8852317;R-HSA-2574845;R-HSA-170072;R-HSA-3000310;R-HSA-170076;R-HSA-2574840;R-HSA-8852324;R-HSA-162657;R-HSA-170087;R-HSA-4088024;R-HSA-170084;R-HSA-170088;R-HSA-8852331;R-HSA-380272;R-HSA-8852337;R-HSA-8852351;R-HSA-4088134;R-HSA-2562526;R-HSA-4088130;R-HSA-69756;R-HSA-380283;R-HSA-8853496
## 21 R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174058;R-HSA-174122;R-HSA-174251;R-HSA-9686969;R-HSA-174120;R-HSA-174121;R-HSA-174057;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437
## 22 R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174058;R-HSA-174122;R-HSA-174251;R-HSA-9686969;R-HSA-174120;R-HSA-174121;R-HSA-174057;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437
## 23 R-HSA-3785711;R-HSA-69562;R-HSA-187934;R-HSA-4647594
## 24 R-HSA-174144;R-HSA-174119;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174132;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421
## 25 R-HSA-984671;R-HSA-984606;R-HSA-983259;R-HSA-990489;R-HSA-984648;R-HSA-983266;R-HSA-984609;R-HSA-984689
## 26 R-HSA-170055;R-HSA-170087;R-HSA-170116;R-HSA-4088024;R-HSA-170084;R-HSA-170149;R-HSA-170088;R-HSA-170153;R-HSA-170057;R-HSA-170158;R-HSA-170126;R-HSA-170159;R-HSA-170156;R-HSA-170131;R-HSA-170161;R-HSA-170070;R-HSA-170072;R-HSA-69756;R-HSA-170076;R-HSA-170044
## 27 R-HSA-174144;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421
## 28 R-HSA-75809;R-HSA-5683735;R-HSA-69891;R-HSA-75010;R-HSA-8852354;R-HSA-170055;R-HSA-176298;R-HSA-75016;R-HSA-9029987;R-HSA-170070;R-HSA-75028;R-HSA-8852337;R-HSA-8852351;R-HSA-176318
## 29 R-HSA-3790137;R-HSA-3790130;R-HSA-3788725;R-HSA-4647594;R-HSA-3788724;R-HSA-3788745;R-HSA-3229089;R-HSA-3222593;R-HSA-3223200;R-HSA-3788748;R-HSA-3785711;R-HSA-3240295;R-HSA-3788705;R-HSA-69562;R-HSA-187934;R-HSA-3788708;R-HSA-3229102
## 30 R-HSA-179410;R-HSA-179417;R-HSA-179421
## 31 R-HSA-211239;R-HSA-266204;R-HSA-211247
## 32 R-HSA-6811426;R-HSA-6811423
## 33 R-HSA-4647594
## 34 R-HSA-170070;R-HSA-170055
## 35 R-HSA-174209;R-HSA-174122;R-HSA-174251;R-HSA-141423;R-HSA-174159;R-HSA-188371;R-HSA-141429;R-HSA-174139;R-HSA-174203;R-HSA-174235;R-HSA-174174;R-HSA-174079;R-HSA-141437
## 36 R-HSA-141429;R-HSA-141423;R-HSA-141437
## 37 R-HSA-141423;R-HSA-141437
## 38 R-HSA-69005;R-HSA-68940;R-HSA-68944;R-HSA-9749253;R-HSA-69015;R-HSA-9749197;R-HSA-69019;R-HSA-68954;R-HSA-9749320;R-HSA-9757257;R-HSA-9757258;R-HSA-68960;R-HSA-68712;R-HSA-176942;R-HSA-9749350;R-HSA-9749286;R-HSA-68914;R-HSA-9749351;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-176956;R-HSA-9749098;R-HSA-169468
## 39 R-HSA-187520;R-HSA-69191;R-HSA-8942607;R-HSA-69195;R-HSA-68940;R-HSA-69199;R-HSA-157906;R-HSA-8941915;R-HSA-68954;R-HSA-8942803;R-HSA-188386;R-HSA-68960;R-HSA-187552;R-HSA-188390;R-HSA-8964588;R-HSA-1363314;R-HSA-113638;R-HSA-9018017;R-HSA-69227;R-HSA-8964580;R-HSA-68914;R-HSA-1363303;R-HSA-8964475;R-HSA-68917;R-HSA-187574;R-HSA-68916;R-HSA-187575;R-HSA-68919;R-HSA-68918;R-HSA-1363311;R-HSA-69562;R-HSA-8964531;R-HSA-188350;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095;R-HSA-1363306
## 40 R-HSA-179410;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174255;R-HSA-179421
## 41 R-HSA-6811426;R-HSA-6811423
## 42 R-HSA-984671;R-HSA-984606;R-HSA-983259;R-HSA-990489;R-HSA-1013881;R-HSA-984648;R-HSA-983266;R-HSA-984609;R-HSA-984689
## 43 R-HSA-2245218;R-HSA-2429719;R-HSA-2288097;R-HSA-2301205;R-HSA-2294580;R-HSA-2172678;R-HSA-2294600;R-HSA-2172666;R-HSA-2294574;R-HSA-2294590
## 44 R-HSA-264871;R-HSA-211239;R-HSA-266204;R-HSA-211247
## 45 R-HSA-2514854;R-HSA-2529015;R-HSA-2520883;R-HSA-2529020
## 46 R-HSA-2245218;R-HSA-2430533;R-HSA-2288097;R-HSA-2172194;R-HSA-5229194;R-HSA-2314566;R-HSA-5195402;R-HSA-2172678;R-HSA-2993898;R-HSA-2294600;R-HSA-2294574;R-HSA-5244669;R-HSA-2214351;R-HSA-2990882;R-HSA-2984226;R-HSA-2984220;R-HSA-2429719;R-HSA-380278;R-HSA-2301205;R-HSA-2172183;R-HSA-2294580;R-HSA-2172666;R-HSA-2294590
## 47 R-HSA-2213248
## 48 R-HSA-6791235;R-HSA-6803875;R-HSA-6802973;R-HSA-69562;R-HSA-6798268;R-HSA-187934;R-HSA-6798282
## 49 R-HSA-1363303;R-HSA-8964475;R-HSA-8964588;R-HSA-1363314;R-HSA-1363311;R-HSA-8964531;R-HSA-8964580;R-HSA-1363306
## 50 R-HSA-174119;R-HSA-174132
## 51 R-HSA-6791235;R-HSA-6803875;R-HSA-6798268;R-HSA-6798282
## 52 R-HSA-174171;R-HSA-174104;R-HSA-174255
## 53 R-HSA-174195;R-HSA-9686980;R-HSA-174088;R-HSA-9686969;R-HSA-174105;R-HSA-188191
## 54 R-HSA-8853405;R-HSA-8853419
## 55 R-HSA-174122;R-HSA-174174
## 56 R-HSA-174227;R-HSA-174120;R-HSA-174157
## 57 R-HSA-75809;R-HSA-5683735;R-HSA-69891;R-HSA-170070;R-HSA-75028;R-HSA-75016;R-HSA-9029987
## 58 R-HSA-2984220;R-HSA-2984226
## 59 R-HSA-6811426;R-HSA-6811423
## 60 R-HSA-9624800;R-HSA-9624798;R-HSA-2995376
## 61 R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326
## 62 R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326
## 63 R-HSA-3790137;R-HSA-3788745;R-HSA-3788748;R-HSA-3788705;R-HSA-3790130;R-HSA-3788725;R-HSA-3788724;R-HSA-3788708
## 64 R-HSA-68960;R-HSA-68712;R-HSA-68940;R-HSA-9749253;R-HSA-9749350;R-HSA-9749286;R-HSA-68914;R-HSA-9749351;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-9749197;R-HSA-68954;R-HSA-9749320;R-HSA-9757257;R-HSA-9749098;R-HSA-9757258
## 65 R-HSA-3000319;R-HSA-3002798;R-HSA-4086410;R-HSA-3002811;R-HSA-2562526;R-HSA-2574845;R-HSA-3000327;R-HSA-3000310;R-HSA-2574840
## 66 R-HSA-9670114;R-HSA-163120;R-HSA-606349;R-HSA-606287;R-HSA-9670101;R-HSA-9670149;R-HSA-181450;R-HSA-606289;R-HSA-9686521;R-HSA-163096;R-HSA-176700;R-HSA-606326
## 67 R-HSA-9687377;R-HSA-9659782
## 68 R-HSA-75809;R-HSA-170070;R-HSA-75028;R-HSA-75016;R-HSA-9029987
## 69 R-HSA-156723;R-HSA-156673
## 70 R-HSA-9687377;R-HSA-9659782
## 71 R-HSA-9749253;R-HSA-9749350;R-HSA-9749286;R-HSA-9749351;R-HSA-68712;R-HSA-9749197;R-HSA-9749320;R-HSA-9757257;R-HSA-9749098;R-HSA-9757258
## 72 R-HSA-5666129;R-HSA-9018766;R-HSA-75016;R-HSA-9008258;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-3858475;R-HSA-5671749;R-HSA-9008285;R-HSA-9017488;R-HSA-9692809;R-HSA-9013143;R-HSA-9013161;R-HSA-9009065;R-HSA-9018794;R-HSA-9018538;R-HSA-5666160;R-HSA-9018542;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-9714361;R-HSA-9013159;R-HSA-5666169;R-HSA-9018808;R-HSA-9008315;R-HSA-9013437;R-HSA-190260;R-HSA-9013438;R-HSA-9014449;R-HSA-9018804;R-HSA-9018807;R-HSA-9018806;R-HSA-3451147;R-HSA-9014467;R-HSA-9604831;R-HSA-5625883;R-HSA-9604829;R-HSA-5656070;R-HSA-9009371;R-HSA-9693125;R-HSA-9018334;R-HSA-419166;R-HSA-8980691;R-HSA-5625870;R-HSA-9018325;R-HSA-9011949;R-HSA-5687090;R-HSA-9011950;R-HSA-9009378;R-HSA-9011941;R-HSA-5687099;R-HSA-5671737;R-HSA-5687097;R-HSA-9604834;R-HSA-5671970;R-HSA-9017855;R-HSA-9011966;R-HSA-9011952;R-HSA-749448;R-HSA-9011981;R-HSA-749454;R-HSA-9013004;R-HSA-9011983;R-HSA-749452;R-HSA-3364026;R-HSA-9011975;R-HSA-5625797;R-HSA-5625796;R-HSA-9714694;R-HSA-9013023;R-HSA-9013022;R-HSA-9714691;R-HSA-9011985;R-HSA-9013009;R-HSA-9011984;R-HSA-9696266;R-HSA-749456;R-HSA-9696271;R-HSA-9693198;R-HSA-9014295;R-HSA-9014294;R-HSA-9696268;R-HSA-9714481;R-HSA-9012000;R-HSA-9013024;R-HSA-380073;R-HSA-5625849;R-HSA-379048;R-HSA-5625848;R-HSA-9691174;R-HSA-964800;R-HSA-9604675;R-HSA-9023840;R-HSA-205039;R-HSA-5625784;R-HSA-374251;R-HSA-9023846;R-HSA-9018745;R-HSA-9693282;R-HSA-9018746;R-HSA-9023859;R-HSA-5625774;R-HSA-9023860;R-HSA-9013111;R-HSA-9013110
## 73 R-HSA-2172194;R-HSA-2314566;R-HSA-2172183;R-HSA-2214351
## 74 R-HSA-212263;R-HSA-212222;R-HSA-212269;R-HSA-212252
## 75 R-HSA-187552;R-HSA-187520;R-HSA-174273;R-HSA-174054;R-HSA-176942;R-HSA-69005;R-HSA-187948;R-HSA-187916;R-HSA-187949;R-HSA-68944;R-HSA-187574;R-HSA-187575;R-HSA-69015;R-HSA-174164;R-HSA-69019;R-HSA-187934;R-HSA-174110;R-HSA-176956;R-HSA-169468
## 76 R-HSA-68944;R-HSA-69015;R-HSA-69019;R-HSA-176942;R-HSA-69005;R-HSA-176956;R-HSA-169468
## 77 R-HSA-4641350;R-HSA-5228525;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355
## 78 R-HSA-174224;R-HSA-174070
## 79 R-HSA-68944;R-HSA-69015;R-HSA-69019;R-HSA-69005
## 80 R-HSA-8868340;R-HSA-8863011;R-HSA-8863674;R-HSA-9710490
## 81 R-HSA-9013437;R-HSA-9013438;R-HSA-9693198
## 82 R-HSA-188386;R-HSA-68960;R-HSA-187552;R-HSA-187520;R-HSA-188390;R-HSA-69191;R-HSA-113638;R-HSA-69195;R-HSA-68940;R-HSA-69199;R-HSA-157906;R-HSA-68914;R-HSA-68917;R-HSA-187574;R-HSA-68916;R-HSA-187575;R-HSA-68919;R-HSA-68918;R-HSA-68954;R-HSA-69562;R-HSA-188350
## 83 R-HSA-9009065;R-HSA-9011981;R-HSA-9011949;R-HSA-9011983;R-HSA-9011950;R-HSA-9012000;R-HSA-9023840;R-HSA-9009378;R-HSA-9008258;R-HSA-9011941;R-HSA-9011975;R-HSA-9023846;R-HSA-9009371;R-HSA-9008315;R-HSA-9008285;R-HSA-9018334;R-HSA-9011966;R-HSA-9011985;R-HSA-9011952;R-HSA-9011984;R-HSA-9023859;R-HSA-9018325;R-HSA-9023860
## 84 R-HSA-9013004;R-HSA-9013009;R-HSA-8980691;R-HSA-8981637
## 85 R-HSA-912408;R-HSA-912470;R-HSA-912467;R-HSA-912450
## 86 R-HSA-9670114;R-HSA-163120;R-HSA-9670149;R-HSA-9670101;R-HSA-181450;R-HSA-163096;R-HSA-9686521;R-HSA-176700
## 87 R-HSA-9822185
## 88 R-HSA-2984220;R-HSA-5229194;R-HSA-5195402;R-HSA-2993898;R-HSA-5244669;R-HSA-2990882;R-HSA-2984226
## 89 R-HSA-174144;R-HSA-174202;R-HSA-174121
## 90 R-HSA-181450;R-HSA-176700
## 91 R-HSA-73718
## 92 R-HSA-5334097;R-HSA-5334160;R-HSA-5334099;R-HSA-5334179;R-HSA-5334164;R-HSA-5334151;R-HSA-5334152
## 93 R-HSA-9013023;R-HSA-9013022;R-HSA-9013024
## 94 R-HSA-69015;R-HSA-69005
## 95 R-HSA-9629195;R-HSA-9629373
## 96 R-HSA-5625797;R-HSA-5625796;R-HSA-5671749;R-HSA-75016;R-HSA-5625870;R-HSA-5625774;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883;R-HSA-5671737
## 97 R-HSA-9714361;R-HSA-9013111;R-HSA-9013110
## 98 R-HSA-75010;R-HSA-176298;R-HSA-176318
## 99 R-HSA-9749197;R-HSA-9749098
## 100 R-HSA-176942;R-HSA-176956;R-HSA-169468
## 101 R-HSA-9629372
## 102 R-HSA-264871;R-HSA-211239;R-HSA-266204;R-HSA-211247
## 103 R-HSA-8852324;R-HSA-8852306;R-HSA-8852354;R-HSA-8852337;R-HSA-8852351;R-HSA-8852317;R-HSA-8852331;R-HSA-8852362;R-HSA-8852298;R-HSA-8852280
## 104 R-HSA-8852130;R-HSA-8852129;R-HSA-8852127;R-HSA-8942099;R-HSA-8942101
## 105 R-HSA-427527;R-HSA-427514;R-HSA-427528
## 106 R-HSA-9629216;R-HSA-9629483
## 107 R-HSA-9624800;R-HSA-9624798;R-HSA-2995376
## 108 R-HSA-5684071;R-HSA-5684052;R-HSA-5684096;R-HSA-5684081
## 109 R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9629373
## 110 R-HSA-912408;R-HSA-912458;R-HSA-912503;R-HSA-912470;R-HSA-912496;R-HSA-912467;R-HSA-1214188;R-HSA-912450
## 111 R-HSA-9670114;R-HSA-9670149;R-HSA-9670101
## 112 R-HSA-427383;R-HSA-427336
## 113 R-HSA-5625797;R-HSA-5625796;R-HSA-5625870;R-HSA-5625774;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883
## 114 R-HSA-9822597;R-HSA-9817458;R-HSA-9822591;R-HSA-9817471;R-HSA-9817513;R-HSA-9817512
## 115 R-HSA-5662614;R-HSA-5662598;R-HSA-5662595;R-HSA-5662608;R-HSA-5662986
## 116 R-HSA-9629497
## 117 R-HSA-9629497;R-HSA-9629372
## 118 R-HSA-9710490
## 119 R-HSA-9659782
## 120 R-HSA-9659782
## 121 R-HSA-9018808;R-HSA-9714694;R-HSA-9714691;R-HSA-9018804;R-HSA-9018807;R-HSA-9018806
## 122 R-HSA-5686900;R-HSA-5686704;R-HSA-5693599;R-HSA-5686685
## 123 R-HSA-9013004;R-HSA-9018766;R-HSA-9014467;R-HSA-8981637;R-HSA-9013145;R-HSA-9013144;R-HSA-9714694;R-HSA-9013023;R-HSA-9693125;R-HSA-9013022;R-HSA-9714691;R-HSA-9013009;R-HSA-9017488;R-HSA-9696266;R-HSA-8980691;R-HSA-9692809;R-HSA-9696271;R-HSA-9693198;R-HSA-9014295;R-HSA-9013143;R-HSA-9014294;R-HSA-9696268;R-HSA-9013161;R-HSA-9018794;R-HSA-9714481;R-HSA-9013024;R-HSA-9017507;R-HSA-9014434;R-HSA-9013157;R-HSA-9714361;R-HSA-9013159;R-HSA-9018745;R-HSA-9018808;R-HSA-9693282;R-HSA-9018746;R-HSA-9013437;R-HSA-9691174;R-HSA-9013438;R-HSA-9014449;R-HSA-9018804;R-HSA-9013111;R-HSA-9018807;R-HSA-9018806;R-HSA-9013110
## 124 R-HSA-912458;R-HSA-912503;R-HSA-912496;R-HSA-1214188
## 125 R-HSA-9687377
## 126 R-HSA-8964588;R-HSA-8964580
## 127 R-HSA-69562;R-HSA-187934
## 128 R-HSA-264871;R-HSA-211239;R-HSA-266204;R-HSA-211247
## 129 R-HSA-74986
## 130 R-HSA-5662614;R-HSA-5662598;R-HSA-5662595;R-HSA-5662608;R-HSA-5662986
## 131 R-HSA-5250938
## 132 R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9629497;R-HSA-9629372;R-HSA-9629373
## 133 R-HSA-5617877;R-HSA-5617492;R-HSA-5617431;R-HSA-5621010;R-HSA-5617874;R-HSA-6810159;R-HSA-6810158;R-HSA-5617887;R-HSA-5617862;R-HSA-6810161;R-HSA-5617859;R-HSA-5617484;R-HSA-5617676;R-HSA-5693644;R-HSA-5617486;R-HSA-5617672;R-HSA-5617483;R-HSA-5617867;R-HSA-5621002;R-HSA-5617866;R-HSA-5617462;R-HSA-5617650;R-HSA-5617661;R-HSA-5617471;R-HSA-5617445;R-HSA-5617452;R-HSA-5617454;R-HSA-6810139;R-HSA-5617641;R-HSA-5617896;R-HSA-5617642
## 134 R-HSA-5617877;R-HSA-5617492;R-HSA-5617431;R-HSA-5621010;R-HSA-5617874;R-HSA-6810159;R-HSA-6810158;R-HSA-5617887;R-HSA-5617862;R-HSA-6810161;R-HSA-5617859;R-HSA-5617484;R-HSA-5617676;R-HSA-5693644;R-HSA-5617486;R-HSA-5617672;R-HSA-5617483;R-HSA-5617867;R-HSA-5621002;R-HSA-5617866;R-HSA-5617462;R-HSA-5617650;R-HSA-5617661;R-HSA-5617471;R-HSA-5617445;R-HSA-5617452;R-HSA-5617454;R-HSA-6810139;R-HSA-5617641;R-HSA-5617896;R-HSA-5617642
## 135 R-HSA-3777129;R-HSA-3782637;R-HSA-3782655;R-HSA-3769447
## 136 R-HSA-9018538;R-HSA-9017855;R-HSA-9018542
## 137 R-HSA-6797766;R-HSA-6805109;R-HSA-6797763;R-HSA-6791235;R-HSA-6803875;R-HSA-6805103;R-HSA-6802973;R-HSA-6793661;R-HSA-69562;R-HSA-6798268;R-HSA-187934;R-HSA-6798282
## 138 R-HSA-5229194;R-HSA-5195402;R-HSA-5244669
## 139 R-HSA-5671970
## 140 R-HSA-4570485;R-HSA-4641350;R-HSA-5228525;R-HSA-4570496;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355
## 141 R-HSA-3364026;R-HSA-3451147
## 142 R-HSA-9009065;R-HSA-9011981;R-HSA-9011949;R-HSA-9011983;R-HSA-9011950;R-HSA-9012000;R-HSA-9023840;R-HSA-9009378;R-HSA-9008258;R-HSA-9011941;R-HSA-9011975;R-HSA-9023846;R-HSA-9009371;R-HSA-9008315;R-HSA-9008285;R-HSA-9018334;R-HSA-9011966;R-HSA-9011985;R-HSA-9011952;R-HSA-9011984;R-HSA-9023859;R-HSA-9018325;R-HSA-9023860
## 143 R-HSA-5683735;R-HSA-5682967;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5682588;R-HSA-5682586;R-HSA-5683930;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5693583;R-HSA-5683405;R-HSA-5682992;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5682983;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-5693549;R-HSA-5682858
## 144 R-HSA-9604834;R-HSA-9604675;R-HSA-9018538;R-HSA-9017855;R-HSA-9018542;R-HSA-9604831;R-HSA-9604829
## 145 R-HSA-8964475;R-HSA-8964531
## 146 R-HSA-5684071;R-HSA-5684052;R-HSA-5684096;R-HSA-5684081
## 147 R-HSA-5662614;R-HSA-3790137;R-HSA-5662608;R-HSA-3790130;R-HSA-3788725;R-HSA-3788724;R-HSA-3229089;R-HSA-5662598;R-HSA-3223200;R-HSA-5662595;R-HSA-3785711;R-HSA-3240295;R-HSA-3788705;R-HSA-187934;R-HSA-9633742;R-HSA-5662986;R-HSA-3788708;R-HSA-3229102;R-HSA-9633008;R-HSA-4647594;R-HSA-3788745;R-HSA-3222593;R-HSA-3788748;R-HSA-69562;R-HSA-9634669;R-HSA-9633005
## 148 R-HSA-8865505
## 149 R-HSA-4570485;R-HSA-4641350;R-HSA-5228525;R-HSA-4570496;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355
## 150 R-HSA-380294;R-HSA-380272;R-HSA-380303
## 151 R-HSA-380272;R-HSA-380303
## 152 R-HSA-5684071;R-HSA-5684052;R-HSA-5684096;R-HSA-5684081
## 153 R-HSA-6797766;R-HSA-6797763
## 154 R-HSA-5683735;R-HSA-5682967;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5682588;R-HSA-5682586;R-HSA-5683930;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5693583;R-HSA-5683405;R-HSA-5682992;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5682983;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-5693549;R-HSA-5682858
## 155 R-HSA-8936584;R-HSA-8936616;R-HSA-8937097;R-HSA-8937037;R-HSA-8936621;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-8937016;R-HSA-8937113;R-HSA-8937050;R-HSA-8935740;R-HSA-8936989;R-HSA-8937118;R-HSA-8937022;R-HSA-8935730;R-HSA-8936979;R-HSA-8935731;R-HSA-8936628;R-HSA-8936599
## 156 R-HSA-9822597;R-HSA-9819200;R-HSA-9817458;R-HSA-9822591;R-HSA-9817471;R-HSA-9822335;R-HSA-9817513;R-HSA-9822185;R-HSA-9817512
## 157 R-HSA-264871
## 158 R-HSA-8868340;R-HSA-8863011;R-HSA-8863674
## 159 R-HSA-8868340;R-HSA-8863011;R-HSA-8863674
## 160 R-HSA-5227490;R-HSA-433672;R-HSA-427337
## 161 R-HSA-427383;R-HSA-5250938;R-HSA-427336
## 162 R-HSA-5578742
## 163 R-HSA-380311;R-HSA-380455;R-HSA-380283
## 164 R-HSA-912408;R-HSA-912458;R-HSA-912503;R-HSA-912470;R-HSA-912496;R-HSA-912467;R-HSA-1214188;R-HSA-912450
## 165 R-HSA-380311;R-HSA-380455;R-HSA-380294;R-HSA-380272;R-HSA-380303;R-HSA-380283
## 166 R-HSA-8852130;R-HSA-8852129;R-HSA-8852127
## 167 R-HSA-8868340;R-HSA-8863011;R-HSA-8863674
## 168 R-HSA-73718;R-HSA-74986
## 169 R-HSA-163120;R-HSA-163096;R-HSA-9686521
## 170 R-HSA-73718;R-HSA-74986
## 171 R-HSA-8853429;R-HSA-8853444
## 172 R-HSA-163010
## 173 R-HSA-2213248;R-HSA-983147;R-HSA-199050;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 174 R-HSA-188386;R-HSA-157906;R-HSA-187552;R-HSA-187520;R-HSA-188390;R-HSA-187574;R-HSA-187575;R-HSA-69191;R-HSA-69195;R-HSA-69562;R-HSA-188350;R-HSA-69199
## 175 R-HSA-427527;R-HSA-427514;R-HSA-5227490;R-HSA-433672;R-HSA-427528;R-HSA-427337
## 176 R-HSA-9604834;R-HSA-9604831;R-HSA-9604829
## 177 R-HSA-68960;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-68954;R-HSA-68940
## 178 R-HSA-9018538;R-HSA-9018542
## 179 R-HSA-977224
## 180 R-HSA-187552;R-HSA-187520;R-HSA-174273;R-HSA-174054;R-HSA-187574;R-HSA-187575;R-HSA-174164;R-HSA-187934;R-HSA-174110;R-HSA-187948;R-HSA-187916;R-HSA-187949
## 181 R-HSA-9714481;R-HSA-9014295;R-HSA-9014294
## 182 R-HSA-176942;R-HSA-176956;R-HSA-169468
## 183 R-HSA-9013161;R-HSA-9692809;R-HSA-9013157;R-HSA-9013159
## 184 R-HSA-69756
## 185 R-HSA-6805109;R-HSA-6805103
## 186 R-HSA-380316;R-HSA-380508
## 187 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 188 R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9629497;R-HSA-9629372;R-HSA-9629373
## 189 R-HSA-2990882
## 190 R-HSA-5683735;R-HSA-5682967;R-HSA-5684052;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5693599;R-HSA-5682588;R-HSA-5686685;R-HSA-5682586;R-HSA-5683930;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5684096;R-HSA-5693583;R-HSA-5683405;R-HSA-5686900;R-HSA-5686704;R-HSA-5682992;R-HSA-5684081;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5684071;R-HSA-5682983;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-5693549;R-HSA-5682858
## 191 R-HSA-9696271
## 192 R-HSA-188390
## 193 R-HSA-9007901
## 194 R-HSA-9696266
## 195 R-HSA-8865491;R-HSA-8865505;R-HSA-8865498
## 196 R-HSA-984671;R-HSA-984606;R-HSA-202704;R-HSA-202727;R-HSA-983259;R-HSA-990489;R-HSA-1013881;R-HSA-984648;R-HSA-983266;R-HSA-202718;R-HSA-984609;R-HSA-984689
## 197 R-HSA-9693282;R-HSA-9693125
## 198 R-HSA-5334097;R-HSA-427527;R-HSA-5334160;R-HSA-5334099;R-HSA-212263;R-HSA-5334164;R-HSA-5250938;R-HSA-5227490;R-HSA-433672;R-HSA-212269;R-HSA-427528;R-HSA-427336;R-HSA-427337;R-HSA-427383;R-HSA-5334179;R-HSA-5334151;R-HSA-5334152;R-HSA-427514;R-HSA-212222;R-HSA-212252
## 199 R-HSA-8848316;R-HSA-8848314;R-HSA-8940998
## 200 R-HSA-187937;R-HSA-187959
## 201 R-HSA-3790130
## 202 R-HSA-5144542;R-HSA-3301345;R-HSA-3321975;R-HSA-3662335;R-HSA-3697008;R-HSA-3697920;R-HSA-3321883;R-HSA-3662318;R-HSA-3318415;R-HSA-3321805
## 203 R-HSA-3229089;R-HSA-3222593;R-HSA-3223200;R-HSA-3240295;R-HSA-3229102
## 204 R-HSA-9604834;R-HSA-9604831;R-HSA-9604829
## 205 R-HSA-3790137;R-HSA-9633008;R-HSA-3790130;R-HSA-3788725;R-HSA-4647594;R-HSA-3788724;R-HSA-3788745;R-HSA-3229089;R-HSA-3222593;R-HSA-3223200;R-HSA-3788748;R-HSA-3785711;R-HSA-3240295;R-HSA-3788705;R-HSA-69562;R-HSA-187934;R-HSA-9633742;R-HSA-3788708;R-HSA-9634669;R-HSA-3229102;R-HSA-9633005
## 206 R-HSA-8941915;R-HSA-8942607;R-HSA-9018017;R-HSA-69227;R-HSA-8942803;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095
## 207 R-HSA-8941915;R-HSA-8942607;R-HSA-9018017;R-HSA-69227;R-HSA-8942803;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095
## 208 R-HSA-9013145;R-HSA-9013144;R-HSA-9691174;R-HSA-9013143
## 209 R-HSA-5578742
## 210 R-HSA-113638
## 211 R-HSA-446694;R-HSA-446692;R-HSA-446862;R-HSA-446894;R-HSA-446701;R-HSA-446634;R-HSA-8940998;R-HSA-8937656;R-HSA-9681763;R-HSA-8950681;R-HSA-446868;R-HSA-450133;R-HSA-6790036;R-HSA-9007901;R-HSA-446684;R-HSA-445757;R-HSA-8848316;R-HSA-6788346;R-HSA-8848314;R-HSA-445752;R-HSA-446648;R-HSA-445753
## 212 R-HSA-6811426;R-HSA-6811423
## 213 R-HSA-5696960;R-HSA-5690080;R-HSA-5697009;R-HSA-5696958
## 214 R-HSA-8942099;R-HSA-8942101
## 215 R-HSA-9009065;R-HSA-9011981;R-HSA-9011949;R-HSA-9011983;R-HSA-9011950;R-HSA-9012000;R-HSA-9023840;R-HSA-9009378;R-HSA-9008258;R-HSA-9011941;R-HSA-9011975;R-HSA-9023846;R-HSA-9009371;R-HSA-9008315;R-HSA-9008285;R-HSA-9018334;R-HSA-9011966;R-HSA-9011985;R-HSA-9011952;R-HSA-9011984;R-HSA-9023859;R-HSA-9018325;R-HSA-9023860
## 216 R-HSA-6790036;R-HSA-6788346
## 217 R-HSA-187552;R-HSA-187520;R-HSA-187574;R-HSA-187575
## 218 R-HSA-2430533
## 219 R-HSA-174058;R-HSA-174057
## 220 R-HSA-163120;R-HSA-163096;R-HSA-9686521
## 221 R-HSA-5656070;R-HSA-190260
## 222 R-HSA-69562;R-HSA-187934
## 223 R-HSA-69562;R-HSA-187934
## 224 R-HSA-69562;R-HSA-187934
## 225 R-HSA-68944
## 226 R-HSA-8950681
## 227 R-HSA-194674;R-HSA-194698
## 228 R-HSA-9014449;R-HSA-9014467;R-HSA-9014434
## 229 R-HSA-2160915;R-HSA-2160884;R-HSA-2160892
## 230 R-HSA-9727567
## 231 R-HSA-6797766;R-HSA-6797763
## 232 R-HSA-8950681
## 233 R-HSA-8937656
## 234 R-HSA-6805109;R-HSA-6805103;R-HSA-6793661
## 235 R-HSA-2160915;R-HSA-2160884;R-HSA-2160892
## 236 R-HSA-113638
## 237 R-HSA-8950681
## 238 R-HSA-8936584;R-HSA-8937097;R-HSA-6803875;R-HSA-8937037;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-8937113;R-HSA-8937050;R-HSA-6805109;R-HSA-8865491;R-HSA-8936989;R-HSA-382096;R-HSA-8937118;R-HSA-6793661;R-HSA-6798268;R-HSA-8936979;R-HSA-187934;R-HSA-8865498;R-HSA-8936599;R-HSA-8936616;R-HSA-6797766;R-HSA-6797763;R-HSA-6791235;R-HSA-8936621;R-HSA-8865505;R-HSA-376419;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-9018594;R-HSA-6798282;R-HSA-8937016;R-HSA-8935740;R-HSA-8937022;R-HSA-6802973;R-HSA-8935730;R-HSA-69562;R-HSA-8935731;R-HSA-8936628
## 239 R-HSA-5656070;R-HSA-190260
## 240 R-HSA-9619024
## 241 R-HSA-5696960;R-HSA-5690080;R-HSA-5697009;R-HSA-5696958
## 242 R-HSA-6802973
## 243 R-HSA-9017855
## 244 R-HSA-6811426;R-HSA-6811423
## 245 R-HSA-5661124;R-HSA-5661125;R-HSA-5423117
## 246 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 247 R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 248 R-HSA-9614816;R-HSA-9621073;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096
## 249 R-HSA-3364026;R-HSA-3451147
## 250 R-HSA-446694;R-HSA-446692;R-HSA-446862;R-HSA-446894;R-HSA-446701;R-HSA-1031716;R-HSA-446634;R-HSA-8940998;R-HSA-1031713;R-HSA-8937656;R-HSA-9681763;R-HSA-8950681;R-HSA-446868;R-HSA-450133;R-HSA-6790036;R-HSA-9007901;R-HSA-446684;R-HSA-445757;R-HSA-8848316;R-HSA-6788346;R-HSA-8848314;R-HSA-445752;R-HSA-446648;R-HSA-445753
## 251 R-HSA-264871
## 252 R-HSA-3858475;R-HSA-3364026;R-HSA-3451147
## 253 R-HSA-9018794
## 254 R-HSA-9018594
## 255 R-HSA-390470
## 256 R-HSA-8936584;R-HSA-8937097;R-HSA-6803875;R-HSA-8937037;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-8937113;R-HSA-8937050;R-HSA-6805109;R-HSA-8865491;R-HSA-8936989;R-HSA-382096;R-HSA-8937118;R-HSA-6793661;R-HSA-6798268;R-HSA-8936979;R-HSA-187934;R-HSA-8865498;R-HSA-8936599;R-HSA-8936616;R-HSA-6797766;R-HSA-6797763;R-HSA-6791235;R-HSA-8936621;R-HSA-8865505;R-HSA-376419;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-9018594;R-HSA-6798282;R-HSA-8937016;R-HSA-8935740;R-HSA-8937022;R-HSA-6802973;R-HSA-8935730;R-HSA-69562;R-HSA-8935731;R-HSA-8936628
## 257 R-HSA-9696268
## 258 R-HSA-6793661
## 259 R-HSA-9018766
## 260 R-HSA-6793661
## 261 R-HSA-9819200;R-HSA-9822335
## 262 R-HSA-5651654;R-HSA-5423038;R-HSA-5651657
## 263 R-HSA-3321975;R-HSA-3782655;R-HSA-5212679;R-HSA-3662335;R-HSA-3697008;R-HSA-5205798;R-HSA-3321883;R-HSA-5205861;R-HSA-5423038;R-HSA-5661126;R-HSA-3777129;R-HSA-5144542;R-HSA-5651654;R-HSA-5661124;R-HSA-5661125;R-HSA-3301345;R-HSA-3782637;R-HSA-3697920;R-HSA-3662318;R-HSA-3318415;R-HSA-3769447;R-HSA-5423117;R-HSA-5651657;R-HSA-3321805
## 264 R-HSA-3321975;R-HSA-3782655;R-HSA-5212679;R-HSA-3662335;R-HSA-3697008;R-HSA-5205798;R-HSA-3321883;R-HSA-5205861;R-HSA-5423038;R-HSA-5661126;R-HSA-3777129;R-HSA-5144542;R-HSA-5651654;R-HSA-5661124;R-HSA-5661125;R-HSA-3301345;R-HSA-3782637;R-HSA-3697920;R-HSA-3662318;R-HSA-3318415;R-HSA-3769447;R-HSA-5423117;R-HSA-5651657;R-HSA-3321805
## 265 R-HSA-8936584;R-HSA-5334097;R-HSA-8937097;R-HSA-427527;R-HSA-5334099;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-433672;R-HSA-427528;R-HSA-8937113;R-HSA-6805109;R-HSA-8936989;R-HSA-382096;R-HSA-8937118;R-HSA-8936979;R-HSA-187934;R-HSA-8936599;R-HSA-212252;R-HSA-8936616;R-HSA-6797766;R-HSA-5578742;R-HSA-212263;R-HSA-6797763;R-HSA-6791235;R-HSA-8936621;R-HSA-8936608;R-HSA-8936481;R-HSA-5250938;R-HSA-8936995;R-HSA-5227490;R-HSA-6798282;R-HSA-212269;R-HSA-8937016;R-HSA-8935740;R-HSA-8937022;R-HSA-8935730;R-HSA-69562;R-HSA-8935731;R-HSA-8936628;R-HSA-5334160;R-HSA-6803875;R-HSA-8937037;R-HSA-5334164;R-HSA-427336;R-HSA-427337;R-HSA-8937050;R-HSA-8865491;R-HSA-5334151;R-HSA-5334152;R-HSA-6793661;R-HSA-6798268;R-HSA-8865498;R-HSA-8865505;R-HSA-376419;R-HSA-74986;R-HSA-9018594;R-HSA-427383;R-HSA-5334179;R-HSA-73718;R-HSA-6802973;R-HSA-427514;R-HSA-212222
## 266 R-HSA-8936584;R-HSA-8936616;R-HSA-8937097;R-HSA-8937037;R-HSA-8936621;R-HSA-8865505;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-8937016;R-HSA-8937113;R-HSA-8937050;R-HSA-8935740;R-HSA-8865491;R-HSA-8936989;R-HSA-8937118;R-HSA-8937022;R-HSA-8935730;R-HSA-8936979;R-HSA-8935731;R-HSA-8936628;R-HSA-8865498;R-HSA-8936599
## 267 R-HSA-446862;R-HSA-199050;R-HSA-6800426;R-HSA-8940998;R-HSA-6799350;R-HSA-8950681;R-HSA-446868;R-HSA-450133;R-HSA-9007901;R-HSA-446684;R-HSA-6788346;R-HSA-446694;R-HSA-2213248;R-HSA-446692;R-HSA-983147;R-HSA-2559439;R-HSA-446894;R-HSA-983140;R-HSA-446701;R-HSA-1031716;R-HSA-446634;R-HSA-1031713;R-HSA-8937656;R-HSA-9681763;R-HSA-6790036;R-HSA-983157;R-HSA-983156;R-HSA-445757;R-HSA-8848316;R-HSA-6798747;R-HSA-8848314;R-HSA-445752;R-HSA-446648;R-HSA-983152;R-HSA-445753
## 268 R-HSA-5661126;R-HSA-5212679;R-HSA-5205798;R-HSA-5205861
## 269 R-HSA-5683735;R-HSA-5682967;R-HSA-5684052;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5693599;R-HSA-5682588;R-HSA-5686685;R-HSA-5682586;R-HSA-5683930;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5684096;R-HSA-5693583;R-HSA-9629195;R-HSA-5683405;R-HSA-5686900;R-HSA-5686704;R-HSA-5682992;R-HSA-5684081;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-9629497;R-HSA-5683384;R-HSA-9629372;R-HSA-5683385;R-HSA-9629373;R-HSA-5682598;R-HSA-5684071;R-HSA-5682983;R-HSA-9629216;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-9629483;R-HSA-5693549;R-HSA-5682858
## 270 R-HSA-174209;R-HSA-174203;R-HSA-174159
## 271 R-HSA-8854044;R-HSA-8854041;R-HSA-8853496
## 272 R-HSA-445077;R-HSA-445071
## 273 R-HSA-9614816;R-HSA-9621073;R-HSA-9698928;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096
## 274 R-HSA-9604675
## 275 R-HSA-9017488;R-HSA-9017507
## 276 R-HSA-4570485;R-HSA-4570496
## 277 R-HSA-9018745;R-HSA-9018746
## 278 R-HSA-205039
## 279 R-HSA-9698928
## 280 R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152
## 281 R-HSA-1031716;R-HSA-1031713
## 282 R-HSA-446694;R-HSA-446692;R-HSA-446862;R-HSA-446894;R-HSA-446701;R-HSA-446634;R-HSA-8940998;R-HSA-9681763;R-HSA-446868;R-HSA-450133;R-HSA-9007901;R-HSA-446684;R-HSA-445757;R-HSA-8848316;R-HSA-8848314;R-HSA-445752;R-HSA-446648;R-HSA-445753
## 283 R-HSA-1655833
## 284 R-HSA-9749792
## 285 R-HSA-205039
## 286 R-HSA-374251;R-HSA-964800
## 287 R-HSA-382096;R-HSA-376419
## 288 R-HSA-216082;R-HSA-202704;R-HSA-202727;R-HSA-216069;R-HSA-199050;R-HSA-202718
## 289 R-HSA-419166
## 290 R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009
## 291 R-HSA-1655833
## 292 R-HSA-5656070;R-HSA-190260
## 293 R-HSA-9604675
## 294 R-HSA-390470
## 295 R-HSA-156915;R-HSA-156912;R-HSA-156923;R-HSA-156907
## 296 R-HSA-3858475
## 297 R-HSA-9018594
## 298 R-HSA-927789
## 299 R-HSA-156915;R-HSA-156912;R-HSA-156923;R-HSA-156907
## 300 R-HSA-390470
## 301 R-HSA-141671;R-HSA-141691;R-HSA-141673
## 302 R-HSA-72673
## 303 R-HSA-5687090;R-HSA-5687099;R-HSA-5687097
## 304 R-HSA-1183058;R-HSA-560472;R-HSA-560473;R-HSA-560491;R-HSA-560493;R-HSA-560510;R-HSA-381309;R-HSA-1183003;R-HSA-560498;R-HSA-560517
## 305 R-HSA-5656070;R-HSA-190260
## 306 R-HSA-205039
## 307 R-HSA-2408529;R-HSA-5333615
## 308 R-HSA-192704;R-HSA-192841
## 309 R-HSA-8956040;R-HSA-8956200;R-HSA-8955289;R-HSA-8955241;R-HSA-8952618;R-HSA-8956026;R-HSA-8952620
## 310 R-HSA-9633008;R-HSA-9633742;R-HSA-9634669;R-HSA-9633005
## 311 R-HSA-1799326;R-HSA-1799330;R-HSA-1799329;R-HSA-1799335;R-HSA-1799332
## 312 R-HSA-72672;R-HSA-72671
## 313 R-HSA-156826
## 314 R-HSA-927836;R-HSA-927789;R-HSA-927832;R-HSA-927813;R-HSA-927889
## 315 R-HSA-927836;R-HSA-927832;R-HSA-927813;R-HSA-927889
## 316 R-HSA-446694;R-HSA-446692;R-HSA-446862;R-HSA-446894;R-HSA-446701;R-HSA-446634;R-HSA-9681763;R-HSA-446868;R-HSA-450133;R-HSA-446684;R-HSA-445757;R-HSA-445752;R-HSA-446648;R-HSA-445753
## 317 R-HSA-8956040;R-HSA-8956200;R-HSA-4641350;R-HSA-8955241;R-HSA-8952618;R-HSA-5228525;R-HSA-8952620;R-HSA-8852130;R-HSA-4570496;R-HSA-8852129;R-HSA-5697009;R-HSA-5696958;R-HSA-4655404;R-HSA-4570485;R-HSA-8955289;R-HSA-8956026;R-HSA-5696960;R-HSA-5690080;R-HSA-8852127;R-HSA-4641342;R-HSA-8942099;R-HSA-4655355;R-HSA-8942101
## 318 R-HSA-72673;R-HSA-72672;R-HSA-156826;R-HSA-72671
## 319 R-HSA-72673;R-HSA-72672;R-HSA-72671
## 320 R-HSA-445077;R-HSA-445071
## 321 R-HSA-9619024
## 322 R-HSA-9727567
## 323 R-HSA-9009282
## 324 R-HSA-2559439
## 325 R-HSA-3858475
## 326 R-HSA-9681763
## 327 R-HSA-1655833;R-HSA-194674;R-HSA-194698
## 328 R-HSA-205039
## 329 R-HSA-192704;R-HSA-192841
## 330 R-HSA-560473;R-HSA-560517
## 331 R-HSA-9633008;R-HSA-9633742;R-HSA-9634669;R-HSA-9633005
## 332 R-HSA-560473;R-HSA-560517
## 333 R-HSA-2408529;R-HSA-5333615
## 334 R-HSA-9014652;R-HSA-9014610
## 335 R-HSA-2160915;R-HSA-2160884;R-HSA-2160892
## 336 R-HSA-6791218
## 337 R-HSA-8956040;R-HSA-4641350;R-HSA-9619024;R-HSA-390470;R-HSA-4570496;R-HSA-1799326;R-HSA-977224;R-HSA-8955289;R-HSA-5696960;R-HSA-8852127;R-HSA-156826;R-HSA-8942099;R-HSA-8942101;R-HSA-72671;R-HSA-8956200;R-HSA-72673;R-HSA-8955241;R-HSA-72672;R-HSA-8952618;R-HSA-5228525;R-HSA-8952620;R-HSA-8852130;R-HSA-141671;R-HSA-8852129;R-HSA-5697009;R-HSA-5696958;R-HSA-156907;R-HSA-141673;R-HSA-4655404;R-HSA-4570485;R-HSA-156915;R-HSA-156912;R-HSA-8956026;R-HSA-5690080;R-HSA-4641342;R-HSA-156923;R-HSA-1799330;R-HSA-141691;R-HSA-1799329;R-HSA-4655355;R-HSA-1799335;R-HSA-1799332
## 338 R-HSA-192704;R-HSA-192841
## 339 R-HSA-2559439
## 340 R-HSA-6791218
## 341 R-HSA-1031716;R-HSA-1031713
## 342 R-HSA-374251;R-HSA-964800
## 343 R-HSA-9727567
## 344 R-HSA-9014652;R-HSA-9014610
## 345 R-HSA-9749792
## 346 R-HSA-6791218
## 347 R-HSA-199050
## 348 R-HSA-202704;R-HSA-202727;R-HSA-202718
## 349 R-HSA-749448;R-HSA-749452;R-HSA-379048
## 350 R-HSA-5693691
## 351 R-HSA-216082;R-HSA-202704;R-HSA-202727;R-HSA-216069;R-HSA-199050;R-HSA-202718
## 352 R-HSA-9681763;R-HSA-9614816;R-HSA-192704;R-HSA-9621073;R-HSA-9698928;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-192841
## 353 R-HSA-72673;R-HSA-72672;R-HSA-1799326;R-HSA-141671;R-HSA-156907;R-HSA-141673;R-HSA-156915;R-HSA-156912;R-HSA-156826;R-HSA-156923;R-HSA-1799330;R-HSA-141691;R-HSA-1799329;R-HSA-1799335;R-HSA-72671;R-HSA-1799332
## 354 R-HSA-445077;R-HSA-9014652;R-HSA-445071;R-HSA-9014610
## 355 R-HSA-5617877;R-HSA-5617492;R-HSA-5617874;R-HSA-445071;R-HSA-1183003;R-HSA-5617887;R-HSA-560517;R-HSA-9822597;R-HSA-5617862;R-HSA-445077;R-HSA-5617859;R-HSA-5617484;R-HSA-5693644;R-HSA-5617486;R-HSA-5617483;R-HSA-5617867;R-HSA-5617866;R-HSA-5617650;R-HSA-5617661;R-HSA-5617641;R-HSA-9817513;R-HSA-5617896;R-HSA-9817512;R-HSA-5617642;R-HSA-1183058;R-HSA-5617431;R-HSA-5621010;R-HSA-6810159;R-HSA-6810158;R-HSA-560472;R-HSA-560473;R-HSA-9819200;R-HSA-6810161;R-HSA-5617676;R-HSA-9014610;R-HSA-5617672;R-HSA-5621002;R-HSA-5617462;R-HSA-560491;R-HSA-560493;R-HSA-8865505;R-HSA-9817458;R-HSA-5617471;R-HSA-9822591;R-HSA-9817471;R-HSA-9822335;R-HSA-5617445;R-HSA-9014652;R-HSA-560510;R-HSA-381309;R-HSA-5617452;R-HSA-560498;R-HSA-5617454;R-HSA-6810139;R-HSA-9822185
## 356 R-HSA-5687090;R-HSA-5687099;R-HSA-5687097
## 357 R-HSA-374251;R-HSA-964800
## 358 R-HSA-445077;R-HSA-9014652;R-HSA-445071;R-HSA-9014610
## 359 R-HSA-749454;R-HSA-749456;R-HSA-380073
## 360 R-HSA-749448;R-HSA-749454;R-HSA-749452;R-HSA-419166;R-HSA-749456;R-HSA-380073;R-HSA-379048;R-HSA-374251;R-HSA-964800
## 361 R-HSA-2160915;R-HSA-2160884;R-HSA-2160892
## 362 R-HSA-6799350;R-HSA-6798747;R-HSA-6800426
## 363 R-HSA-5693691
## 364 R-HSA-749448;R-HSA-749454;R-HSA-749452;R-HSA-419166;R-HSA-749456;R-HSA-380073;R-HSA-379048
## 365 R-HSA-9681763
## 366 R-HSA-9681763;R-HSA-9614816;R-HSA-192704;R-HSA-9621073;R-HSA-9698928;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-192841
## 367 R-HSA-9687377;R-HSA-192704;R-HSA-9621073;R-HSA-9698928;R-HSA-8863011;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-192841;R-HSA-9710490;R-HSA-9681763;R-HSA-9614816;R-HSA-8868340;R-HSA-9659782;R-HSA-8863674
## 368 R-HSA-5656070;R-HSA-190260
## 369 R-HSA-2408529;R-HSA-5333615
## 370 R-HSA-927836;R-HSA-927789;R-HSA-6791218;R-HSA-927832;R-HSA-927813;R-HSA-927889
## 371 R-HSA-1655833;R-HSA-194674;R-HSA-560473;R-HSA-194698;R-HSA-560517
## 372 R-HSA-6799350;R-HSA-2559439;R-HSA-6798747;R-HSA-6800426
## 373 R-HSA-1655833;R-HSA-194674;R-HSA-560473;R-HSA-2160915;R-HSA-2160884;R-HSA-2408529;R-HSA-194698;R-HSA-2160892;R-HSA-560517;R-HSA-5693691;R-HSA-5333615Pathway Involvement:
Cancer Pathways: - Gene sets associated with general cancer pathways (e.g., “pathways in cancer”, “colorectal cancer”) were prominently up-regulated.
This suggests that doxorubicin treatment triggers a broad response in cancer-related cellular activities, potentially reflecting a stress or damage response in the cells.
DNA Damage Response: - Several genes were linked to DNA repair and the cellular response to DNA damage (e.g., “p53 signaling pathway”, “cell cycle”).
Given doxorubicin’s role as a DNA-interacting drug, the up-regulation in these areas aligns with the expected cellular response to DNA damage and the attempt to halt cell cycle progression.
Apoptosis: - Apoptosis-related pathways, such as those related to programmed cell death, were up-regulated.
This suggests that the treatment may induce apoptosis in cells, which is a desired outcome in cancer treatment, as it can lead to the death of cancer cells.
Immune Response: - Up-regulation in immune system-related pathways (e.g., “cytokine-cytokine receptor interaction”, “Toll-like receptor signaling pathway”).
This might indicate an activation of the immune response, which could be either a direct effect of doxorubicin or a secondary response to cellular stress and damage.
Metabolic Changes: - Changes in genes related to metabolism (e.g., “metabolic pathways”, “biosynthesis of antibiotics”).
The metabolic shift might reflect the cell’s effort to manage stress, repair damage, or could indicate changes in energy requirements due to the drug’s impact.
Focusing on the top sets such as cancer pathways, DNA damage response, and apoptosis gives a clear indication that doxorubicin primarily impacts mechanisms central to cell proliferation, survival, and death. The prominence of these pathways among the up-regulated genes signifies a robust cellular response to the drug.
For Q2 and Q3, it will be useful to refer to the “Preprocess the data” and “Reduce dimensionality and visualize cells” sections of the monocle3 vignette (https://cole-trapnell-lab.github.io/monocle3/docs/clustering/#pre-process & https://cole-trapnell-lab.github.io/monocle3/docs/clustering/#reduce-dimension).
Links to an external site.
As we explored in Assignments #1 and #2, your dataset contains cells exposed to a treatment (i.e., doxorubicin or TGF-b exposure) that leads to changes in the expression of many genes. In addition, the cells in your dataset have been genetically perturbed by the expression of the nuclease Cas9 and a single guide RNA (sgRNA) targeting a gene of interest or a nontargeting control sgRNA (unperturbed cells). In Q2 and Q3 of this assignment, you will explore how genetic perturbation alters the response of cells to exposure.
Q2. Dimensionality reduction and visualization using Uniform Manifold Projection and Approximation (UMAP). Q2-1. Use the monocle3 function preprocess_cds to perform principal component analysis (PCA) of your dataset using genes expressed in 5% or more of the cells as feature genes (identified in Assignment #2). You can pass a character vector of ensemble gene ids to preproccess_cds via use_genes.
cds <- detect_genes(cds)
cds_subset <- cds[rowData(cds)$num_cells_expressed>=3018*0.05]
genelist = row.names(rowData(cds_subset))
cds <- preprocess_cds(cds, method = 'PCA',use_genes = genelist)
plot_pc_variance_explained(cds)
cds <- reduce_dimension(cds)## No preprocess_method specified, using preprocess_method = 'PCA'After pre-processing via PCA, apply UMAP to visualize your dataset in 2 dimensions using the monocle3 function reduce_dimension. Use the function plot_cells to plot and save the resulting UMAP coloring cells by the treatment they were exposed to. How does the distribution of cells across UMAP space vary by exposure? [5 pts]. Note: it may be useful to define the color of the cells by treatment by passing scale_color_manual to your ggplot2 code (see below). Cells on the left and those on the small upper-right island have been treated with doxorubicin. The clear separation of these cells by treatment suggests that doxorubicin significantly alters gene expression.
plot_cells(cds, color_cells_by = "treatment") +
scale_color_manual(values = c("black", "red"))## No trajectory to plot. Has learn_graph() been called yet?
Q2-2. Using the monocle3 function plot_cells, visualize the expression of the marker genes that you examined in Assignment #1 Q2-3 on your UMAP. For dataset 1, plot the expression levels of CDKN1A and PMAIP1. For dataset 2, plot the expression levels of CDH1 and FN1. How does the expression of these genes relate to the distribution of cells in UMAP space? Do all treatment-exposed cells partition across areas of low or high marker expression as you would expect given exposure? [10 pts].
In the case of the CDKN1A gene, there is a noticeable increase in expression among cells exposed to treatment, indicating a higher prevalence of this gene’s activation in response to the treatment. Under the mock treatment, some cells do not express CDKN1A gene.
For the PMAIP1 gene, the majority of cells subjected to treatment exhibit little to no expression, suggesting a varied or limited activation of this gene in the treated cell population.
plot_cells(cds, genes = 'CDKN1A') ## No trajectory to plot. Has learn_graph() been called yet?
plot_cells(cds, genes = 'PMAIP1') ## No trajectory to plot. Has learn_graph() been called yet?
Q2-3. Cluster cells with similar gene expression patterns using the monocle3 function cluster_cells specifying PCA as the reduction_method and a resolution parameter of 0.001. cluster_cells uses an algorithm called Leiden community detection to identify local cell relationships (i.e., cell clusters). Annotate your colData using the output of the monocle3 function clusters (specifying PCA as the reduction_method, i.e., reduction_method == “PCA”) to include, for every cell, which cluster a cell belongs to, respectively. *Note: a vector such as the output of clusters can be added to a colData DFrame object by using the $ operator (e.g., colData(cds)$new_column = new_column).
cds <- cluster_cells(cds,reduction_method = 'PCA',resolution = 0.001)
cell_clusters <- clusters(cds, reduction_method = "PCA")
colData(cds)$cluster_id = cell_clusters
plot_cells(cds,color_cells_by = "cluster_id")## No trajectory to plot. Has learn_graph() been called yet?
How many unique clusters are in your dataset? Generate a bar plot of the frequency of cells across clusters to examine how treatment-exposed cells partition across your clusters. Is the distribution of treated and untreated cells similar across exposures? [10 pts].
There are 2 clusters in my dataset. Cells that get treated are more expressed in cluster2. Cells in cluster 1 are more to be mock.
plot_data <- as.data.frame(table(colData(cds)$cluster_id, colData(cds)$treatment))
names(plot_data) <- c("Cluster", "Treatment", "Frequency")
# Generate the bar plot
ggplot(plot_data, aes(x = Cluster, y = Frequency, fill = Treatment)) +
geom_bar(stat = "identity", position = position_dodge()) +
theme_minimal() +
labs(x = "Cluster", y = "Number of Cells", title = "Frequency of Cells Across Clusters by Treatment Status")
Q3. Effect of genetic perturbation on drug-induced phenotypes.
Q3-1. The gene column in colData refers to the gene targeted by the sgRNA identified for each cell in your dataset. Similar to Q1-3, generate a bar plot to examine the distribution of genetically perturbed and unperturbed cells across cell clusters. Are all genotypes distributed similarly to nontargeting control sgRNA-expressing cells? [5 pts].
library(dplyr)
library(ggplot2)
df <- as.data.frame(colData(cds))
cell_proportion_df <- df %>% group_by(gene,cluster_id) %>% dplyr::summarize(cells_per_cluster = n()) %>% group_by(cluster_id) %>% mutate(freq_per_cluster = cells_per_cluster/sum(cells_per_cluster))## `summarise()` has grouped output by 'gene'. You can override using the
## `.groups` argument.ggplot(cell_proportion_df, aes(x =cluster_id, y = freq_per_cluster, fill =gene)) + geom_bar(stat = "identity",position = position_dodge())
One sgRNA TP53 show to have more counts in cluster 2. NonTageting also
shows a little higher in cluster 1. while other target genes shows to
have slightly larger amount of cells in cluster 1, but similar
distribution.
Q3-2. Focusing on the subset of cells exposed to treatment in your dataset (i.e., excluding untreated mock controls), use violin plots to examine the expression of the marker genes from Assignment #2 Q1-2 (dataset 1: CDKN1A and PMAIP1, dataset 2: CDH1 and FN1) for your dataset (remember to add a pseudocount of 1). Are the differences statistically significant? Is the effect consistent with the drug’s mechanism of action and the molecular role of the sgRNA-targeted gene? Focus on the sgRNA-targeted gene that appears to have the largest effect on marker expression compared to nontargeting control sgRNA-expressing cells [10 pts].
While doing pairwise significant test, sgRNA TP53 is signifantly different from other sgRNA under the two marker genes, with a significant lower expression under marker CDKN1A, and significant higher expression under marker marker PMAIP1.
NONTARGETING vs TP53 under marker CDKN1A: p.adjust = 9.023874e-35 NONTARGETING vs TP53 under marker PMAIP1: p.adjust = 1.301841e-26
The marker should focus on is CDKN1A.
Lower Expression of CDKN1A in TP53-Targeted Cells: CDKN1A is a cyclin-dependent kinase inhibitor induced by TP53, which leads to cell cycle arrest in the G1 phase. A significant lower expression of CDKN1A upon TP53 perturbation suggests that the pathway for cell cycle arrest is disrupted when TP53 function is compromised. Doxorubicin’s mechanism of action, which involves DNA intercalation and topoisomerase II inhibition, typically results in DNA damage that would normally activate TP53, leading to increased CDKN1A expression. The observation of lower CDKN1A expression in cells with TP53 targeted by sgRNA is consistent with the disruption of the normal TP53-mediated DNA damage response due to doxorubicin.
treated_cds = cds[,colData(cds)$treatment == "doxorubicin"]
plot_genes_violin(treated_cds[rowData(treated_cds)$gene_short_name == "CDKN1A",], group_cells_by = "gene", pseudocount = 1) + ggpubr::stat_compare_means(method = "kruskal.test",label = "p.signif")## Warning: Transformation introduced infinite values in continuous y-axis
cdkn1a_data <- treated_cds[rowData(treated_cds)$gene_short_name == "CDKN1A",]
expression_values <- exprs(cdkn1a_data) + 1
df_for_test <- data.frame(
sgRNA = colData(cdkn1a_data)$gene,
expression = as.numeric(expression_values)
)
df_for_test$sgRNA <- factor(df_for_test$sgRNA)
pairwise_combinations <- combn(levels(df_for_test$sgRNA), 2, simplify = FALSE)
pairwise_results <- lapply(pairwise_combinations, function(sgRNA_pair) {
data_subset <- df_for_test %>% filter(sgRNA %in% sgRNA_pair)
test_result <- wilcox.test(expression ~ sgRNA, data = data_subset)
c(sgRNA_pair = paste(sgRNA_pair, collapse = " vs "), p.value = test_result$p.value)
})
pairwise_results_df <- do.call(rbind.data.frame, pairwise_results)
names(pairwise_results_df) <- c("sgRNA1_vs_sgRNA2", "p.value")
pairwise_results_df$p.adjusted <- p.adjust(pairwise_results_df$p.value, method = "BH")
pairwise_results_df$significant <- ifelse(pairwise_results_df$p.adjusted >= 0.01, 'ns',
ifelse(pairwise_results_df$p.adjusted < 0.01 & pairwise_results_df$p.adjusted >= 0.001, '**',
ifelse(pairwise_results_df$p.adjusted < 0.001 & pairwise_results_df$p.adjusted >= 0.0001, '***',
'****')))
print(pairwise_results_df)## sgRNA1_vs_sgRNA2 p.value p.adjusted significant
## 1 ARID1B vs ATM 0.88205448651685 8.820545e-01 ns
## 2 ARID1B vs BRCA1 0.28183287827297 4.227493e-01 ns
## 3 ARID1B vs GATA3 0.0332118418309993 6.974487e-02 ns
## 4 ARID1B vs NONTARGETING 0.0145933808272736 4.378014e-02 ns
## 5 ARID1B vs RB1 0.0904550367645191 1.582963e-01 ns
## 6 ARID1B vs TP53 1.03671352174363e-17 7.256995e-17 ****
## 7 ATM vs BRCA1 0.244781298052596 3.954159e-01 ns
## 8 ATM vs GATA3 0.029025213572714 6.772550e-02 ns
## 9 ATM vs NONTARGETING 0.019512418894997 5.122010e-02 ns
## 10 ATM vs RB1 0.0870411335486839 1.582963e-01 ns
## 11 ATM vs TP53 1.74785742231724e-14 6.117501e-14 ****
## 12 BRCA1 vs GATA3 0.351964362138761 4.927501e-01 ns
## 13 BRCA1 vs NONTARGETING 0.420076086081105 5.513499e-01 ns
## 14 BRCA1 vs RB1 0.524891918901282 6.483959e-01 ns
## 15 BRCA1 vs TP53 4.36123530893236e-15 1.831719e-14 ****
## 16 GATA3 vs NONTARGETING 0.765549275651384 8.580820e-01 ns
## 17 GATA3 vs RB1 0.776359910191848 8.580820e-01 ns
## 18 GATA3 vs TP53 2.2231027574493e-20 2.334258e-19 ****
## 19 NONTARGETING vs RB1 0.876643614037782 8.820545e-01 ns
## 20 NONTARGETING vs TP53 4.29708267072921e-36 9.023874e-35 ****
## 21 RB1 vs TP53 6.48772705288101e-17 3.406057e-16 ****plot_genes_violin(treated_cds[rowData(treated_cds)$gene_short_name == "PMAIP1",], group_cells_by = "gene", pseudocount = 1) + ggpubr::stat_compare_means(method = "kruskal.test",label = "p.signif")## Warning: Transformation introduced infinite values in continuous y-axis
PMAIP1_data <- treated_cds[rowData(treated_cds)$gene_short_name == "PMAIP1",]
expression_values <- exprs(PMAIP1_data) + 1
df_for_test <- data.frame(
sgRNA = colData(PMAIP1_data)$gene,
expression = as.numeric(expression_values)
)
df_for_test$sgRNA <- factor(df_for_test$sgRNA)
pairwise_combinations <- combn(levels(df_for_test$sgRNA), 2, simplify = FALSE)
pairwise_results <- lapply(pairwise_combinations, function(sgRNA_pair) {
data_subset <- df_for_test %>% filter(sgRNA %in% sgRNA_pair)
test_result <- wilcox.test(expression ~ sgRNA, data = data_subset)
c(sgRNA_pair = paste(sgRNA_pair, collapse = " vs "), p.value = test_result$p.value)
})
pairwise_results_df <- do.call(rbind.data.frame, pairwise_results)
names(pairwise_results_df) <- c("sgRNA1_vs_sgRNA2", "p.value")
pairwise_results_df$p.adjusted <- p.adjust(pairwise_results_df$p.value, method = "BH")
pairwise_results_df$significant <- ifelse(pairwise_results_df$p.adjusted >= 0.01, 'ns',
ifelse(pairwise_results_df$p.adjusted < 0.01 & pairwise_results_df$p.adjusted >= 0.001, '**',
ifelse(pairwise_results_df$p.adjusted < 0.001 & pairwise_results_df$p.adjusted >= 0.0001, '***',
'****')))
print(pairwise_results_df)## sgRNA1_vs_sgRNA2 p.value p.adjusted significant
## 1 ARID1B vs ATM 0.810275467943497 8.738242e-01 ns
## 2 ARID1B vs BRCA1 0.344216748630971 6.023793e-01 ns
## 3 ARID1B vs GATA3 0.631848352752773 8.621246e-01 ns
## 4 ARID1B vs NONTARGETING 0.733329471464278 8.738242e-01 ns
## 5 ARID1B vs RB1 0.124436682333731 2.375609e-01 ns
## 6 ARID1B vs TP53 5.00096009653806e-18 5.251008e-17 ****
## 7 ATM vs BRCA1 0.518806835902843 7.782103e-01 ns
## 8 ATM vs GATA3 0.832213486274174 8.738242e-01 ns
## 9 ATM vs NONTARGETING 0.98584524145914 9.858452e-01 ns
## 10 ATM vs RB1 0.115790972160581 2.375609e-01 ns
## 11 ATM vs TP53 1.41916733078511e-13 5.960503e-13 ****
## 12 BRCA1 vs GATA3 0.656856865769364 8.621246e-01 ns
## 13 BRCA1 vs NONTARGETING 0.445982194604697 7.204328e-01 ns
## 14 BRCA1 vs RB1 0.0294781749005882 8.843452e-02 ns
## 15 BRCA1 vs TP53 2.22316399343699e-14 1.167161e-13 ****
## 16 GATA3 vs NONTARGETING 0.806687157333005 8.738242e-01 ns
## 17 GATA3 vs RB1 0.0720873369065165 1.682038e-01 ns
## 18 GATA3 vs TP53 1.22479511648321e-14 8.573566e-14 ****
## 19 NONTARGETING vs RB1 0.0448689779166985 1.177811e-01 ns
## 20 NONTARGETING vs TP53 6.19924062168798e-28 1.301841e-26 ****
## 21 RB1 vs TP53 3.4515818149084e-09 1.208054e-08 ****Q3-3. Re-plot your UMAP from Q1, visualizing only the subset of treatment-exposed cells expressing non-targeting control sgRNAs and sgRNAs against the gene identified in Q2-2. Do all cells for each genotype co-segregate in UMAP space? Do you observe any heterogeneity in how cells partition across UMAP space? Given the marker expression plots from Q1-2, are all cells for a given genotype responding equally? [10 pts]. Note: it may be useful to define the color of the cells by genotype yourself using scale_color_manual (see below).
Cells of different genetypes are mixed, while genetype TP53 is isolated from other cells.
The isolation of TP53-perturbed cells might indicate that the perturbation of this gene triggers a robust cellular response, which could include activation of DNA damage pathways, cell cycle arrest, or induction of apoptosis, depending on the nature of the perturbation and the cellular context.
Marker PMAIP1 is more enriched in TP53-perturbed cells, while marker CDKN1A is evenly distributed.
PMAIP1, a pro-apoptotic marker, being more enriched in TP53-perturbed cells, is consistent with the known activation of apoptotic pathways following TP53 perturbation. This could indicate that despite the sgRNA perturbation, the cells are still capable of initiating apoptosis, potentially through TP53-independent pathways or due to incomplete silencing of TP53.
CDKN1A (p21), a cell cycle regulator, being evenly distributed, could suggest that the TP53 perturbation does not significantly disrupt the cell cycle control mechanisms or that there is compensation from other pathways maintaining cell cycle control.
treated_cds <- preprocess_cds(treated_cds)
plot_pc_variance_explained(treated_cds)
treated_cds <- reduce_dimension(treated_cds,reduction_method = c("UMAP"))## No preprocess_method specified, using preprocess_method = 'PCA'plot_cells(treated_cds, color_cells_by="gene")+theme(legend.position = "right")## No trajectory to plot. Has learn_graph() been called yet?
plot_cells(treated_cds, genes = 'PMAIP1')## No trajectory to plot. Has learn_graph() been called yet?
plot_cells(treated_cds, genes = 'CDKN1A')## No trajectory to plot. Has learn_graph() been called yet?
Selecting only the non-targeting control sgRNAs and TP53 sgRNAs. Cells
get well seperated. marker PMAIP1 does not show up in all cells, only
concentrated in TP53 sgRNAs. marker CDKN1A is generally same expressed
under this two sgRNAs.
Bonus. Generate a violin plot of the expression of the top upregulated, and top downregulated gene in response to exposure for your dataset (from Assignment #2) as a function of both genotype (gene in colData) and treatment (treatment in colData, remember to add a pseudocount of 1). [2 pts].
df_sorted[1,]## id gene_short_name num_cells_expressed gene_id
## 29060 ENSG00000130513 GDF15 758 ENSG00000130513
## status term estimate std_err test_val p_value
## 29060 OK treatmentdoxorubicin 5.033202 0.207235 24.28741 2.662886e-130
## normalized_effect model_component q_value
## 29060 6.540556 count 1.205473e-129df_sorted[nrow(df_sorted),]## id gene_short_name num_cells_expressed gene_id status
## 9659 ENSG00000072571 HMMR 945 ENSG00000072571 OK
## term estimate std_err test_val p_value
## 9659 treatmentdoxorubicin -2.468685 0.1165883 -21.17438 1.645399e-99
## normalized_effect model_component q_value
## 9659 -3.407544 count 5.701253e-99cdstop1 <- cds[rowData(cds)$gene_short_name =='GDF15',]
cdsdown1 <- cds[rowData(cds)$gene_short_name =='HMMR',]plot_genes_violin(cdstop1, group_cells_by = "treatment", pseudocount = 1)## Warning: Transformation introduced infinite values in continuous y-axis
plot_genes_violin(cdstop1, group_cells_by = "gene", pseudocount = 1)## Warning: Transformation introduced infinite values in continuous y-axis
plot_genes_violin(cdsdown1, group_cells_by = "treatment", pseudocount = 1)## Warning: Transformation introduced infinite values in continuous y-axis
plot_genes_violin(cdsdown1, group_cells_by = "gene", pseudocount = 1)## Warning: Transformation introduced infinite values in continuous y-axis